Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5068582..5068727 Replicon chromosome
Accession NZ_CP024038
Organism Klebsiella pneumoniae strain QS17-0029

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5068589..5068691 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5068582..5068727 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CR230_RS25675 5064113..5065546 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CR230_RS25680 5065662..5065901 + 240 WP_002911393.1 YebV family protein -
CR230_RS25685 5065999..5066190 + 192 WP_002911395.1 YebW family protein -
CR230_RS25690 5066187..5066840 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
CR230_RS25695 5066997..5067965 + 969 WP_004151446.1 VirK/YbjX family protein -
CR230_RS29065 5068070..5068213 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5068582..5068727 + 146 - - Antitoxin
- 5068589..5068691 - 103 - - Toxin
CR230_RS25705 5068850..5069188 - 339 WP_009307539.1 YebY family protein -
CR230_RS25710 5069205..5070074 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
CR230_RS25715 5070078..5070452 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CR230_RS25720 5070565..5070795 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CR230_RS25725 5070874..5071533 + 660 WP_002911407.1 exodeoxyribonuclease X -
CR230_RS25730 5071537..5073597 - 2061 WP_094083900.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T86605 NZ_CP024038:c5068691-5068589 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT86605 NZ_CP024038:5068582-5068727 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References