Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 4689252..4689805 Replicon chromosome
Accession NZ_CP024025
Organism Pseudomonas protegens strain DTU9.1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CLA18_RS21150 Protein ID WP_241110180.1
Coordinates 4689252..4689506 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CLA18_RS21155 Protein ID WP_102864761.1
Coordinates 4689533..4689805 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLA18_RS21135 (CLA18_21050) 4685189..4686562 - 1374 WP_265577269.1 restriction endonuclease subunit S -
CLA18_RS21140 (CLA18_21055) 4686552..4688291 - 1740 WP_265577270.1 class I SAM-dependent DNA methyltransferase -
CLA18_RS21145 (CLA18_21060) 4688782..4689174 + 393 WP_265577271.1 DUF3077 domain-containing protein -
CLA18_RS21150 (CLA18_21065) 4689252..4689506 - 255 WP_241110180.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CLA18_RS21155 (CLA18_21070) 4689533..4689805 - 273 WP_102864761.1 CopG family ribbon-helix-helix protein Antitoxin
CLA18_RS21160 (CLA18_21075) 4690166..4692199 - 2034 WP_265577272.1 LTA synthase family protein -
CLA18_RS21165 (CLA18_21080) 4692249..4692860 - 612 WP_265577273.1 hypothetical protein -
CLA18_RS21170 (CLA18_21085) 4692860..4694155 - 1296 WP_265577274.1 sialidase family protein -
CLA18_RS21175 (CLA18_21090) 4694201..4694746 - 546 WP_265577275.1 cytochrome b/b6 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9828.21 Da        Isoelectric Point: 4.9002

>T86589 WP_241110180.1 NZ_CP024025:c4689506-4689252 [Pseudomonas protegens]
MERCRQFLVEKGPLIAQRAAQVIERQIARLEEDPEIGRPFPELPELRELIIEFGDSGYVALYRHERADDAVYILAFRHQK
EAGY

Download         Length: 255 bp

>T86589 NZ_CP024025:c4689506-4689252 [Pseudomonas protegens]
TTGGAGCGTTGTCGCCAGTTTCTAGTCGAGAAAGGCCCGCTGATCGCTCAACGAGCTGCCCAAGTGATTGAGCGTCAAAT
CGCTCGACTGGAGGAAGACCCAGAAATCGGTCGTCCTTTTCCAGAACTGCCGGAGCTGCGCGAGCTGATCATCGAGTTCG
GTGATTCGGGTTATGTCGCACTTTATCGGCATGAGCGTGCGGATGATGCTGTTTACATACTTGCCTTTCGGCATCAGAAA
GAAGCCGGTTACTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10466.69 Da        Isoelectric Point: 6.0866

>AT86589 WP_102864761.1 NZ_CP024025:c4689805-4689533 [Pseudomonas protegens]
MATSIKIDDELKKRIQHLAGLRQRSSHWIMREAIAQYVEREEAREGFKQEALASWAAYQETGRHLTGEETRAWLNTWGTE
AEAELPKCHD

Download         Length: 273 bp

>AT86589 NZ_CP024025:c4689805-4689533 [Pseudomonas protegens]
ATGGCCACTTCTATCAAGATTGATGACGAGCTGAAAAAACGCATTCAGCATCTGGCGGGACTGCGTCAACGTTCGTCCCA
CTGGATTATGCGCGAAGCAATAGCGCAGTACGTCGAGCGCGAGGAAGCCCGTGAGGGCTTCAAACAAGAAGCCTTGGCGT
CGTGGGCGGCGTATCAGGAAACGGGTCGGCATCTGACCGGCGAAGAAACTCGGGCCTGGCTCAATACCTGGGGTACCGAG
GCTGAGGCGGAGCTGCCTAAGTGCCACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References