Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3276470..3277745 Replicon chromosome
Accession NZ_CP024025
Organism Pseudomonas protegens strain DTU9.1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CLA18_RS15180 Protein ID WP_053151131.1
Coordinates 3277146..3277745 (+) Length 200 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CLA18_RS15175 Protein ID WP_265578236.1
Coordinates 3276470..3277027 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLA18_RS15145 (CLA18_15110) 3271674..3272324 + 651 WP_182999846.1 DUF2239 family protein -
CLA18_RS15150 (CLA18_15115) 3272412..3273032 + 621 WP_072442132.1 LysE family translocator -
CLA18_RS15155 (CLA18_15120) 3273078..3273665 - 588 WP_065363866.1 AidA/PixA family protein -
CLA18_RS15160 (CLA18_15125) 3274125..3275312 + 1188 WP_265578234.1 PrpF domain-containing protein -
CLA18_RS15165 (CLA18_15130) 3275491..3275937 - 447 WP_227454078.1 hypothetical protein -
CLA18_RS15170 (CLA18_15135) 3275939..3276280 - 342 WP_265578235.1 low molecular weight protein tyrosine phosphatase family protein -
CLA18_RS15175 (CLA18_15140) 3276470..3277027 + 558 WP_265578236.1 helix-turn-helix transcriptional regulator Antitoxin
CLA18_RS15180 (CLA18_15145) 3277146..3277745 + 600 WP_053151131.1 HD domain-containing protein Toxin
CLA18_RS15185 (CLA18_15150) 3277960..3280140 + 2181 WP_265578237.1 catalase/peroxidase HPI -
CLA18_RS15190 (CLA18_15155) 3280268..3280696 - 429 WP_258611844.1 hypothetical protein -
CLA18_RS15195 (CLA18_15160) 3281081..3281995 + 915 WP_265578238.1 SGNH/GDSL hydrolase family protein -
CLA18_RS15200 (CLA18_15165) 3282045..3282299 + 255 Protein_2995 IS66 family insertion sequence element accessory protein TnpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-173)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 200 a.a.        Molecular weight: 22458.26 Da        Isoelectric Point: 5.8364

>T86587 WP_053151131.1 NZ_CP024025:3277146-3277745 [Pseudomonas protegens]
MNSELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVVQAAHPDKSQQERADLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDADTQRRLDAQAQAAVQHRLR

Download         Length: 600 bp

>T86587 NZ_CP024025:3277146-3277745 [Pseudomonas protegens]
ATGAACAGTGAACTTCTCAGTGGCCGCCTCGACTTTCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACGGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAGGCCATTCACGGCGACATCCCG
GCGGTGGTCCAGGCCGCCCACCCGGACAAGAGCCAGCAGGAGCGCGCGGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCAACGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGATGCCAGCCCGCTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCAGCATCGGCTGCGCTAA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20381.27 Da        Isoelectric Point: 7.0307

>AT86587 WP_265578236.1 NZ_CP024025:3276470-3277027 [Pseudomonas protegens]
MSVAPFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGQQAMEPAERVRLEQLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSATRAGQFGVPLSELLGQSLWGFCTEEITRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT86587 NZ_CP024025:3276470-3277027 [Pseudomonas protegens]
ATGTCCGTAGCCCCGTTCACCTCTCCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAGCTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGTTGGGAAAACGGCCAGCAGGCCATGGAACCGGCCG
AGCGTGTGCGCCTGGAACAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCGCGGTTGGTGAACGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCAGCGACCCGCGCCGGGCAGTTCGG
CGTGCCCCTGAGTGAGCTGCTGGGCCAGTCCCTGTGGGGCTTTTGCACCGAGGAAATCACCCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGTGAAGTGCTGGCGCCGCCGTCCCTGGAGTTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References