Detailed information of TA system TA086582

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 403653..404169
• Replicon: chromosome
• Accession: NZ_CP024025
• Organism: Pseudomonas protegens strain DTU9.1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CLA18_RS01830
• Protein ID: WP_103740982.1
• Coordinates: 403888..404169 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CLA18_RS01825
• Protein ID: WP_210457792.1
• Coordinates: 403653..403898 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CLA18_RS01810 (CLA18_01815)	401147..402757	+	1611	WP_265577715.1	glycosyltransferase family 39 protein	-
CLA18_RS01815 (CLA18_01820)	402867..403328	+	462	WP_011058532.1	YbaK/EbsC family protein	-
CLA18_RS01820 (CLA18_01825)	403343..403588	+	246	WP_265577716.1	DUF2789 domain-containing protein	-
CLA18_RS01825 (CLA18_01830)	403653..403898	+	246	WP_210457792.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CLA18_RS01830 (CLA18_01835)	403888..404169	+	282	WP_103740982.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CLA18_RS01835 (CLA18_01840)	404312..404740	+	429	WP_011058536.1	winged helix DNA-binding protein	-
CLA18_RS01840 (CLA18_01845)	404737..406824	+	2088	WP_041751900.1	FUSC family protein	-
CLA18_RS01845 (CLA18_01850)	406821..407030	+	210	WP_011058538.1	DUF1656 domain-containing protein	-
CLA18_RS01850 (CLA18_01855)	407027..407917	+	891	WP_011058539.1	HlyD family secretion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10812.70 Da
• Isoelectric Point: 10.2298

>T86582 WP_103740982.1 NZ_CP024025:403888-404169 [Pseudomonas protegens]
MTYSLEFLPSAHKEWSKLGHTLREQFKKKLAERLEVPRIPADALHGLPDCYKIKLKASGYRLVYQVIEERVVVCVVAVGK
RERGTVYEQARKR

Nucleotide

• Length: 282 bp

>T86582 NZ_CP024025:403888-404169 [Pseudomonas protegens]
ATGACTTATAGCCTTGAGTTCCTGCCTTCGGCACACAAGGAATGGAGCAAGTTGGGGCATACGCTTCGAGAGCAATTCAA
GAAAAAGCTCGCCGAACGGCTTGAGGTGCCGCGAATCCCTGCTGATGCCCTGCATGGGCTTCCCGATTGCTACAAAATCA
AACTCAAGGCTTCGGGCTACCGATTGGTTTATCAAGTGATCGAAGAGCGCGTAGTGGTTTGCGTGGTTGCGGTCGGCAAG
CGCGAGCGTGGAACCGTTTACGAGCAGGCCAGGAAACGCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8741.07 Da
• Isoelectric Point: 4.5164

>AT86582 WP_210457792.1 NZ_CP024025:403653-403898 [Pseudomonas protegens]
MQSILADKAVSVSELKKNPSAVLSGAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIIRARSHETPVPVSLDD
L

Nucleotide

• Length: 246 bp

>AT86582 NZ_CP024025:403653-403898 [Pseudomonas protegens]
ATGCAGAGTATTCTGGCTGACAAAGCCGTCAGCGTATCTGAGTTGAAGAAAAACCCTTCTGCCGTCTTGAGTGGTGCCCA
GGGCGGGCCAGTGGCGGTGTTGAATCACAATCGTGTCATGGGCTACATGGTTCCGGCCGAGGTTTTCGAAGCGTTGATGG
AACGCCTGGATGATCTGGAGTTGGCCGAAATCATCCGCGCGCGCAGCCATGAGACGCCCGTTCCGGTCAGTCTGGATGAC
TTATAG