Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 2914339..2914886 | Replicon | chromosome |
Accession | NZ_CP024024 | ||
Organism | Pseudomonas aeruginosa strain PARM801 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | BBX44_RS13660 | Protein ID | WP_121496487.1 |
Coordinates | 2914339..2914614 (-) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | BBX44_RS13665 | Protein ID | WP_121496486.1 |
Coordinates | 2914614..2914886 (-) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BBX44_RS13635 | 2909632..2910678 | - | 1047 | WP_121496492.1 | NAD(P)-dependent oxidoreductase | - |
BBX44_RS13640 | 2910671..2911345 | - | 675 | WP_124083107.1 | hypothetical protein | - |
BBX44_RS13645 | 2911357..2911839 | - | 483 | WP_121496490.1 | adenylyltransferase/cytidyltransferase family protein | - |
BBX44_RS13650 | 2911847..2912350 | - | 504 | WP_121496489.1 | GNAT family N-acetyltransferase | - |
BBX44_RS13655 | 2912340..2913653 | - | 1314 | WP_162950080.1 | aminotransferase class III-fold pyridoxal phosphate-dependent enzyme | - |
BBX44_RS13660 | 2914339..2914614 | - | 276 | WP_121496487.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BBX44_RS13665 | 2914614..2914886 | - | 273 | WP_121496486.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
BBX44_RS13670 | 2915146..2915706 | + | 561 | WP_023102601.1 | recombinase family protein | - |
BBX44_RS13675 | 2915763..2916488 | - | 726 | WP_188129804.1 | hypothetical protein | - |
BBX44_RS13680 | 2916520..2917185 | - | 666 | WP_121496494.1 | DUF3218 family protein | - |
BBX44_RS13685 | 2917196..2918227 | - | 1032 | WP_121496485.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 2851917..2961665 | 109748 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10688.33 Da Isoelectric Point: 10.4249
>T86577 WP_121496487.1 NZ_CP024024:c2914614-2914339 [Pseudomonas aeruginosa]
MELKWTNKGLSDLTRLYEFLAAVNRSAAARTVQQLTSAPTKLLANPRIGERLEEFDPRDVRRILVGHYEMRYEIAGSTIY
LLRLWHTRKDR
MELKWTNKGLSDLTRLYEFLAAVNRSAAARTVQQLTSAPTKLLANPRIGERLEEFDPRDVRRILVGHYEMRYEIAGSTIY
LLRLWHTRKDR
Download Length: 276 bp
>T86577 NZ_CP024024:c2914614-2914339 [Pseudomonas aeruginosa]
ATGGAGTTGAAGTGGACGAACAAGGGGCTGTCCGATCTGACTCGACTATATGAGTTCCTGGCGGCTGTGAACCGTTCCGC
TGCGGCACGTACCGTGCAACAGCTAACGAGCGCACCGACTAAGCTGCTGGCCAACCCGCGCATCGGTGAGCGCCTGGAAG
AGTTCGATCCGCGTGACGTGCGCCGGATTCTGGTCGGGCATTACGAGATGCGCTACGAAATTGCGGGCTCTACCATCTAT
CTGCTGCGTCTGTGGCACACCCGTAAAGATCGCTGA
ATGGAGTTGAAGTGGACGAACAAGGGGCTGTCCGATCTGACTCGACTATATGAGTTCCTGGCGGCTGTGAACCGTTCCGC
TGCGGCACGTACCGTGCAACAGCTAACGAGCGCACCGACTAAGCTGCTGGCCAACCCGCGCATCGGTGAGCGCCTGGAAG
AGTTCGATCCGCGTGACGTGCGCCGGATTCTGGTCGGGCATTACGAGATGCGCTACGAAATTGCGGGCTCTACCATCTAT
CTGCTGCGTCTGTGGCACACCCGTAAAGATCGCTGA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10131.35 Da Isoelectric Point: 4.5127
>AT86577 WP_121496486.1 NZ_CP024024:c2914886-2914614 [Pseudomonas aeruginosa]
MPANAKTRSVTAHVPIELAERVDDIAERLERSKNWIVKQALTAWLDQEDERSRLTREALVDVDDGCVIDHQAVQAWADSL
STDTPLPVPR
MPANAKTRSVTAHVPIELAERVDDIAERLERSKNWIVKQALTAWLDQEDERSRLTREALVDVDDGCVIDHQAVQAWADSL
STDTPLPVPR
Download Length: 273 bp
>AT86577 NZ_CP024024:c2914886-2914614 [Pseudomonas aeruginosa]
ATGCCCGCTAACGCCAAAACCAGATCTGTCACCGCCCATGTCCCCATTGAGCTGGCCGAACGTGTCGATGACATCGCAGA
GCGCCTGGAGCGCTCCAAGAACTGGATCGTCAAGCAGGCTCTTACAGCCTGGCTCGACCAGGAAGACGAGCGTAGCCGCC
TGACCCGCGAGGCTCTGGTGGATGTGGATGACGGCTGCGTGATTGACCATCAGGCAGTCCAGGCCTGGGCCGATAGCCTT
AGTACCGACACTCCGCTGCCGGTGCCGCGCTGA
ATGCCCGCTAACGCCAAAACCAGATCTGTCACCGCCCATGTCCCCATTGAGCTGGCCGAACGTGTCGATGACATCGCAGA
GCGCCTGGAGCGCTCCAAGAACTGGATCGTCAAGCAGGCTCTTACAGCCTGGCTCGACCAGGAAGACGAGCGTAGCCGCC
TGACCCGCGAGGCTCTGGTGGATGTGGATGACGGCTGCGTGATTGACCATCAGGCAGTCCAGGCCTGGGCCGATAGCCTT
AGTACCGACACTCCGCTGCCGGTGCCGCGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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