Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1993862..1995570 Replicon chromosome
Accession NZ_CP023969
Organism Pseudomonas sp. FDAARGOS_380

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag CRN80_RS09300 Protein ID WP_098950023.1
Coordinates 1994692..1995570 (-) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag CRN80_RS09295 Protein ID WP_003195671.1
Coordinates 1993862..1994695 (-) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN80_RS09275 1989065..1990561 - 1497 WP_098950021.1 aldehyde dehydrogenase -
CRN80_RS09280 1990571..1991374 - 804 WP_003195676.1 aspartate dehydrogenase -
CRN80_RS09285 1991385..1993070 - 1686 WP_047712100.1 thiamine pyrophosphate-binding protein -
CRN80_RS09290 1993063..1993860 - 798 WP_098950022.1 SDR family oxidoreductase -
CRN80_RS09295 1993862..1994695 - 834 WP_003195671.1 IclR family transcriptional regulator Antitoxin
CRN80_RS09300 1994692..1995570 - 879 WP_098950023.1 alpha/beta hydrolase Toxin
CRN80_RS09305 1995575..1996114 - 540 WP_032894482.1 cupin domain-containing protein -
CRN80_RS09310 1996128..1996895 - 768 WP_169918545.1 SDR family oxidoreductase -
CRN80_RS09315 1996892..1997668 - 777 WP_032894483.1 ABC transporter permease -
CRN80_RS09320 1997696..1998688 - 993 WP_003195661.1 ABC transporter substrate-binding protein -
CRN80_RS09325 1998728..1999579 - 852 WP_032894485.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(45-276)

Antitoxin

Transcription regulator IclR, N-terminal

(19-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 30822.26 Da        Isoelectric Point: 7.6690

>T86544 WP_098950023.1 NZ_CP023969:c1995570-1994692 [Pseudomonas sp. FDAARGOS_380]
MLPGLSQAAPTADLQAQLERDFPQRLVASAGGQQALRECGAGPVVVLLHGIGSGAASWLQVARQLAPQARVIAWDAPGYG
DSSPLESDAPKAEQYAARLAQMLDALGVEECVLVGHSLGALTALAFARSSQAHRVNRLVLISPARGYGAPALGQQRQQVR
QQRLDNLQRLGIAGLAEQRSAHMLSPRATPQAMAWVRWNMARLNPVGYRQAIELLCGDDLLRHGQPAMPCEVHCGEADSI
TPAEACLSVAKALGASFNLIADAGHASPIEQPQVVAGRLACAIHQSLTGRTL

Download         Length: 879 bp

>T86544 NZ_CP023969:c1995570-1994692 [Pseudomonas sp. FDAARGOS_380]
ATGCTGCCAGGACTCTCTCAAGCCGCGCCGACGGCCGACCTGCAAGCCCAACTGGAGCGTGATTTCCCCCAACGCCTGGT
GGCCTCGGCCGGTGGGCAACAGGCATTGCGTGAATGTGGCGCGGGGCCGGTGGTGGTGCTGCTGCACGGTATCGGCTCCG
GGGCGGCGTCCTGGCTGCAAGTGGCGCGGCAACTGGCGCCCCAGGCCCGGGTTATTGCCTGGGACGCACCCGGCTACGGC
GACTCCAGCCCGCTGGAGTCGGATGCGCCCAAGGCCGAGCAGTACGCAGCCCGTCTGGCGCAGATGCTGGATGCACTGGG
TGTCGAGGAATGTGTGCTGGTCGGCCACTCCCTCGGCGCCCTCACCGCCCTGGCGTTCGCCCGCAGTTCACAGGCCCACC
GCGTCAATCGGCTGGTGCTGATCAGCCCGGCGCGCGGCTACGGCGCACCAGCCCTTGGCCAACAGCGCCAACAGGTGCGT
CAGCAACGCCTGGACAACCTGCAACGCCTGGGCATCGCTGGCCTGGCTGAACAACGCAGCGCCCACATGCTGTCGCCCCG
CGCCACGCCCCAGGCCATGGCCTGGGTGCGTTGGAACATGGCGCGCCTGAACCCCGTGGGTTATCGCCAGGCCATTGAAT
TGCTGTGCGGCGATGACCTGCTGCGCCATGGCCAACCGGCCATGCCCTGCGAGGTGCATTGCGGTGAAGCCGACAGCATC
ACCCCCGCCGAGGCCTGCCTGAGCGTGGCCAAGGCGCTGGGCGCCAGCTTCAACCTGATTGCCGACGCCGGCCACGCCAG
CCCCATCGAGCAACCCCAAGTGGTAGCCGGGCGCCTGGCCTGCGCCATTCATCAATCCCTGACTGGTAGAACCCTATGA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30601.10 Da        Isoelectric Point: 6.9636

>AT86544 WP_003195671.1 NZ_CP023969:c1994695-1993862 [Pseudomonas sp. FDAARGOS_380]
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRVNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVMALFDLVQADRQRGFVSGEGFFESAISTVAAPVRDQSGGIVAALGVTIPTAQIGHVNF
EELLNQVRRSADELSRLLNYNGGAHNGQPRVTALMRD

Download         Length: 834 bp

>AT86544 NZ_CP023969:c1994695-1993862 [Pseudomonas sp. FDAARGOS_380]
ATGAACGATTCCGATCTGCTCAAAGACGCTCAGGACAAATACATCGTTCCAGGCCTGGAGCGCGGCCTGCTCCTGCTCTG
TGAGTTCAGCCGGCGCAACCGCACCCTGACCGCGCCGGAGCTGGCACGTCGGTTGGCACTGCCCCGCTCGACCATTTTCC
GCCTGCTGACCACCCTGGAGACCATGGGCTTCGTCACCCGCAGCGGCAATGAATACCGCCTCGGCATGTCCGTGCTGCGC
CTGGGCTTCGAGTACCTGGCGTCGCTGGAGCTGACCGAACTGGGCCAGCCGTTGCTGGCGCGCTTGTGCGACCGGGTCAA
CTACCCGAGCAACCTGGTGGTGCGTGACGGTCGCTCGATTGTCTACGTGGCCAAGGTTTCACCGCCGTCGGTGTTCTCCA
ACGCGGTCAACGTCGGCACCCGCCTGCCCGCCCACGCCACCGTGCTGGGGCGCATCCTGCTCGAAGACCTGTCGCTGGCC
GAGTTGCGCGAGTTGTACCCCGAAGAGCACTTGGAACAACACTCGCCCTGCACGCCGAAAACCGTGATGGCGCTGTTCGA
CCTGGTCCAGGCCGACCGCCAGCGCGGTTTTGTCAGTGGCGAAGGTTTTTTCGAATCGGCGATTTCCACCGTGGCCGCGC
CCGTGCGTGACCAGAGCGGCGGCATCGTCGCAGCCCTGGGCGTGACCATCCCCACGGCGCAGATCGGCCACGTCAACTTT
GAGGAACTCTTGAATCAGGTCCGGCGCAGCGCCGACGAGTTGTCACGCCTGCTCAACTACAACGGCGGCGCCCATAACGG
TCAGCCGCGCGTCACCGCCTTGATGAGAGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References