Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 2933007..2933687 Replicon chromosome
Accession NZ_CP023962
Organism Yersinia frederiksenii strain FDAARGOS_417

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag CRN74_RS13860 Protein ID WP_098904889.1
Coordinates 2933367..2933687 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag CRN74_RS13855 Protein ID WP_098904888.1
Coordinates 2933007..2933330 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN74_RS13825 2928384..2929007 - 624 Protein_2670 inovirus Gp2 family protein -
CRN74_RS13830 2929553..2930020 + 468 WP_145544613.1 hypothetical protein -
CRN74_RS13835 2930106..2930939 + 834 WP_138070065.1 hypothetical protein -
CRN74_RS13845 2931632..2932453 + 822 Protein_2673 DUF945 domain-containing protein -
CRN74_RS13850 2932524..2932994 + 471 WP_098904887.1 DNA repair protein RadC -
CRN74_RS13855 2933007..2933330 + 324 WP_098904888.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
CRN74_RS13860 2933367..2933687 + 321 WP_098904889.1 TA system toxin CbtA family protein Toxin
CRN74_RS13870 2934187..2934750 - 564 WP_057644656.1 AAA family ATPase -
CRN74_RS13875 2934879..2935247 - 369 WP_050082072.1 RidA family protein -
CRN74_RS13880 2935422..2936267 - 846 WP_098904891.1 hypothetical protein -
CRN74_RS13885 2936264..2936647 - 384 WP_050874201.1 carboxymuconolactone decarboxylase family protein -
CRN74_RS13890 2936601..2937050 - 450 WP_050082076.1 MerR family transcriptional regulator -
CRN74_RS13895 2937323..2937574 + 252 WP_050287084.1 hypothetical protein -
CRN74_RS13900 2937567..2937815 + 249 WP_098904892.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12033.66 Da        Isoelectric Point: 5.9559

>T86503 WP_098904889.1 NZ_CP023962:2933367-2933687 [Yersinia frederiksenii]
MHISTVPATVPVSSRLSPAQVWQQLLTYLLEHHYGLTLNDTPFHDNTAIEEHIDAGITLADAVNFLVERYELVRIDRKGF
TWQEQTPFLTATDILRARRATGIMST

Download         Length: 321 bp

>T86503 NZ_CP023962:2933367-2933687 [Yersinia frederiksenii]
ATGCACATTTCAACTGTACCGGCCACGGTGCCAGTTTCGTCACGTTTGTCGCCCGCGCAGGTCTGGCAGCAACTGTTAAC
GTATCTGCTGGAGCACCATTACGGCCTGACGCTTAACGACACGCCATTCCATGACAACACGGCCATTGAGGAGCATATCG
ACGCAGGAATAACGCTTGCCGATGCGGTTAATTTCTTAGTGGAACGCTATGAACTGGTACGCATCGACCGCAAAGGATTT
ACATGGCAGGAGCAGACGCCGTTCCTGACCGCCACCGATATTCTCAGAGCCAGGCGAGCTACGGGGATAATGAGCACTTA
A

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11949.66 Da        Isoelectric Point: 6.7470

>AT86503 WP_098904888.1 NZ_CP023962:2933007-2933330 [Yersinia frederiksenii]
MSLTPSHEWGLHSDIIPRFGARLVQEGNRLHYLADRAGLTGSFSPIHLQKLDLAFPLLVEQLENMLRAGELNPQQQHQVN
IHLTGLTCIADTRGSCGYVYISIYPTP

Download         Length: 324 bp

>AT86503 NZ_CP023962:2933007-2933330 [Yersinia frederiksenii]
ATGTCATTAACACCATCCCATGAATGGGGGCTGCATAGCGATATCATCCCACGCTTTGGCGCAAGATTGGTTCAGGAAGG
TAACAGGCTGCATTACCTGGCTGACAGGGCTGGATTGACGGGGAGTTTTAGCCCGATACACCTGCAGAAATTAGATCTGG
CTTTCCCGCTATTAGTAGAACAACTGGAAAATATGCTGCGTGCTGGCGAACTAAATCCACAGCAGCAACATCAGGTGAAC
ATTCATCTTACAGGTTTAACCTGCATAGCTGACACCCGTGGTAGCTGCGGTTACGTTTACATTTCTATTTATCCAACCCC
GTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References