86431

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 3037249..3038285 Replicon chromosome
Accession NZ_CP023956
Organism Serratia fonticola strain FDAARGOS_411

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag CRN79_RS13645 Protein ID WP_098929760.1
Coordinates 3037249..3037824 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag CRN79_RS13650 Protein ID WP_098929761.1
Coordinates 3037824..3038285 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN79_RS13620 3032773..3034026 + 1254 WP_098929756.1 L-methionine/branched-chain amino acid transporter -
CRN79_RS13625 3034056..3034331 - 276 WP_024528278.1 accessory factor UbiK family protein -
CRN79_RS13630 3034752..3035405 + 654 WP_098929757.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
CRN79_RS13635 3035466..3036233 - 768 WP_098929758.1 zinc transporter ZupT -
CRN79_RS13640 3036441..3037223 + 783 WP_098929759.1 4,5-DOPA dioxygenase extradiol -
CRN79_RS13645 3037249..3037824 - 576 WP_098929760.1 PIN domain-containing protein Toxin
CRN79_RS13650 3037824..3038285 - 462 WP_098929761.1 helix-turn-helix domain-containing protein Antitoxin
CRN79_RS13655 3038389..3039399 - 1011 WP_065684683.1 LacI family transcriptional regulator -
CRN79_RS13660 3039615..3041381 + 1767 WP_098929762.1 class I mannose-6-phosphate isomerase -
CRN79_RS13665 3041386..3041814 + 429 WP_098929763.1 PTS fructose transporter subunit IIA -
CRN79_RS13670 3041824..3042324 + 501 WP_065684680.1 PTS sugar transporter subunit IIB -
CRN79_RS13675 3042341..3043141 + 801 WP_024483041.1 PTS sugar transporter subunit IIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-115)

Antitoxin

SinI-like, DNA-binding domain

(84-131)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21661.97 Da        Isoelectric Point: 5.2385

>T86431 WP_098929760.1 NZ_CP023956:c3037824-3037249 [Serratia fonticola]
MTHSPYPALLDACVLYPARLRDLLMHLGLRGLYQPKWTAQIHEEWKRNLLVNRRDLQAEQLDRVHALMDKAMPDANVIGH
EQLVDSIRLPDQDDRHVLAAAIIANAEVIVTYNLKDFPVDYLSTFGIEAIHPDDFVSDLIDLNHALALEAVTNLRQALKN
PPMTADSFLASLTQIEMAKTVKALEDYKFIL

Download         Length: 576 bp

>T86431 NZ_CP023956:c3037824-3037249 [Serratia fonticola]
ATGACGCATTCGCCTTACCCAGCATTGCTTGACGCTTGTGTGCTTTACCCAGCAAGACTGCGAGATCTGTTGATGCATTT
AGGCCTAAGAGGTCTTTATCAGCCCAAATGGACAGCGCAAATCCACGAAGAGTGGAAGCGTAATCTACTGGTTAATCGGC
GAGATTTGCAGGCCGAGCAGTTGGATCGCGTTCATGCTCTAATGGATAAGGCAATGCCGGATGCGAATGTAATAGGCCAC
GAACAATTGGTAGACAGCATTAGGTTGCCTGACCAAGACGATCGCCATGTTCTGGCAGCTGCAATAATTGCAAACGCTGA
GGTCATCGTCACTTATAACCTTAAAGACTTTCCGGTAGATTATTTATCGACTTTTGGAATCGAAGCCATACATCCTGACG
ACTTCGTGTCAGACCTTATTGATCTTAACCATGCGTTAGCACTTGAGGCGGTGACAAATCTAAGGCAAGCACTGAAGAAT
CCCCCCATGACAGCGGATAGTTTTCTAGCTTCACTCACTCAAATTGAGATGGCAAAAACGGTTAAGGCATTGGAAGACTA
CAAGTTCATACTATAA

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17281.77 Da        Isoelectric Point: 6.2305

>AT86431 WP_098929761.1 NZ_CP023956:c3038285-3037824 [Serratia fonticola]
MTSATFSKINLPGVQEKEIAQKGYRDLSAMLATKLDIRHFSIRDNEQNEHSIEVPPSAVKMLVEILGELANGNAVQVVPV
HAELTTQEAANLLNVSRPHVVKMLEEGKIEFHKTGRHRRIRFADLMAYKEQRDIEAAAAMDELTRLSQDMDIY

Download         Length: 462 bp

>AT86431 NZ_CP023956:c3038285-3037824 [Serratia fonticola]
ATGACCAGTGCAACTTTTTCCAAAATCAACTTGCCTGGTGTGCAAGAAAAAGAGATTGCCCAAAAAGGTTATCGAGATTT
ATCGGCGATGTTGGCAACAAAACTAGATATTCGCCACTTCTCGATCAGGGACAATGAGCAAAATGAACACTCTATTGAGG
TTCCACCTTCTGCGGTGAAAATGCTCGTTGAGATACTGGGAGAACTAGCAAACGGGAACGCAGTTCAGGTTGTGCCCGTT
CATGCGGAATTGACTACCCAAGAAGCCGCCAATTTACTTAATGTATCCAGGCCGCATGTTGTGAAGATGCTAGAAGAAGG
CAAAATCGAATTCCATAAAACAGGGCGTCATCGCCGCATACGCTTTGCAGACCTTATGGCCTACAAAGAGCAGCGAGACA
TCGAAGCTGCTGCAGCAATGGATGAACTGACTCGTCTTTCACAGGATATGGATATTTATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References