Detailed information of TA system TA086429

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yfjZ-ypjF/CbtA-CbeA
• Location: 2149936..2150703
• Replicon: chromosome
• Accession: NZ_CP023956
• Organism: Serratia fonticola strain FDAARGOS_411

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: CRN79_RS09580
• Protein ID: WP_098929262.1
• Coordinates: 2149936..2150304 (-)
• Length: 123 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: CRN79_RS09585
• Protein ID: WP_098929264.1
• Coordinates: 2150368..2150703 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CRN79_RS09555	2147001..2147381	+	381	WP_192958294.1	hypothetical protein	-
CRN79_RS09560	2147470..2147646	+	177	Protein_1856	RHS repeat-associated core domain-containing protein	-
CRN79_RS09565	2147917..2148142	+	226	Protein_1857	HNH endonuclease	-
CRN79_RS09570	2148149..2148553	+	405	WP_098929258.1	hypothetical protein	-
CRN79_RS09575	2148858..2149712	-	855	WP_098929260.1	DUF4942 domain-containing protein	-
CRN79_RS09580	2149936..2150304	-	369	WP_098929262.1	TA system toxin CbtA family protein	Toxin
CRN79_RS09585	2150368..2150703	-	336	WP_098929264.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
CRN79_RS09590	2150715..2151194	-	480	WP_043140854.1	DNA repair protein RadC	-
CRN79_RS09595	2151377..2151997	-	621	WP_098931781.1	hypothetical protein	-
CRN79_RS09600	2152025..2152579	-	555	WP_044030216.1	hypothetical protein	-
CRN79_RS09605	2152827..2153582	-	756	WP_098931783.1	50S ribosome-binding GTPase	-
CRN79_RS09610	2153791..2154597	-	807	WP_098929266.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2148149..2164828	16679

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-110)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 123 a.a.
• Molecular weight: 13719.74 Da
• Isoelectric Point: 6.7163

>T86429 WP_098929262.1 NZ_CP023956:c2150304-2149936 [Serratia fonticola]
MQILPVTPKQAAYACPSPVIVWQSMLTYLLEQHYGLALNDTEFSDDTVIHEHIDAGISLADALNFTVEKFGLVRTDRRGF
SYREQSPFITAIDILRARRATGLMTRMGYQAITSVIRGEKQA

Nucleotide

• Length: 369 bp

>T86429 NZ_CP023956:c2150304-2149936 [Serratia fonticola]
ATGCAAATCTTACCTGTCACTCCGAAACAGGCGGCTTACGCTTGCCCATCACCCGTTATTGTCTGGCAATCCATGCTCAC
GTATCTGCTGGAACAGCATTACGGATTGGCGCTTAACGATACCGAGTTCAGTGATGACACCGTGATCCACGAACATATTG
ATGCCGGTATTTCCCTGGCTGATGCGTTGAATTTCACAGTGGAAAAGTTTGGCCTGGTTCGCACCGATCGCCGGGGGTTT
TCCTATAGGGAACAATCCCCCTTTATCACGGCTATCGATATTCTCCGTGCCCGTCGAGCTACCGGCCTGATGACCCGTAT
GGGTTACCAGGCCATCACCTCAGTTATCCGGGGAGAAAAGCAGGCATGA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12323.93 Da
• Isoelectric Point: 6.0555

>AT86429 WP_098929264.1 NZ_CP023956:c2150703-2150368 [Serratia fonticola]
MPSIIAPAWGLKRNVTPQFGARLVQEGGRLHFLADRADISGTFSDEQLRDVDNAFPQFINHLELMLLSGELNPRYQHCVT
LYRNGLTCEADSLGSHGYVYLAIYPTPSSTA

Nucleotide

• Length: 336 bp

>AT86429 NZ_CP023956:c2150703-2150368 [Serratia fonticola]
ATGCCATCAATCATTGCCCCGGCCTGGGGACTCAAACGCAACGTCACTCCGCAGTTTGGCGCCCGCCTGGTACAAGAAGG
CGGGCGACTGCACTTCCTGGCTGACCGTGCCGATATCAGCGGTACCTTCAGCGACGAGCAGCTGCGTGATGTAGATAACG
CCTTTCCGCAGTTCATCAACCATTTGGAACTGATGCTGCTTTCTGGTGAGCTCAATCCCCGTTATCAGCATTGCGTCACG
TTGTATCGCAATGGCTTGACCTGTGAGGCCGATAGCCTGGGATCACACGGTTATGTGTATCTCGCCATTTATCCTACGCC
TTCATCAACGGCATAA