Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1942101..1942246 Replicon chromosome
Accession NZ_CP023941
Organism Klebsiella pneumoniae strain FDAARGOS_444

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1942137..1942239 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1942101..1942246 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN70_RS09785 1937231..1939291 + 2061 WP_004151449.1 oligopeptidase B -
CRN70_RS09790 1939295..1939954 - 660 WP_002911407.1 exodeoxyribonuclease X -
CRN70_RS09795 1940033..1940263 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CRN70_RS09800 1940376..1940750 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CRN70_RS09805 1940754..1941623 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CRN70_RS09810 1941640..1941978 + 339 WP_002911404.1 YebY family protein -
- 1942101..1942246 - 146 - - Antitoxin
- 1942137..1942239 + 103 - - Toxin
CRN70_RS30865 1942614..1942757 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CRN70_RS09820 1942862..1943830 - 969 WP_004151446.1 VirK/YbjX family protein -
CRN70_RS09825 1943987..1944640 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
CRN70_RS09830 1944637..1944828 - 192 WP_002911395.1 YebW family protein -
CRN70_RS09835 1944926..1945165 - 240 WP_002911393.1 YebV family protein -
CRN70_RS09840 1945281..1946714 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T86382 NZ_CP023941:1942137-1942239 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT86382 NZ_CP023941:c1942246-1942101 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References