Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 929870..930015 Replicon chromosome
Accession NZ_CP023913
Organism Klebsiella pneumoniae strain FDAARGOS_439

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 929906..930008 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 929870..930015 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRN23_RS04465 925000..927060 + 2061 WP_004151449.1 oligopeptidase B -
CRN23_RS04470 927064..927723 - 660 WP_002911407.1 exodeoxyribonuclease X -
CRN23_RS04475 927802..928032 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CRN23_RS04480 928145..928519 + 375 WP_039819395.1 CopC domain-containing protein YobA -
CRN23_RS04485 928523..929392 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
CRN23_RS04490 929409..929747 + 339 WP_002911404.1 YebY family protein -
- 929870..930015 - 146 - - Antitoxin
- 929906..930008 + 103 - - Toxin
CRN23_RS29740 930384..930527 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
CRN23_RS04500 930632..931600 - 969 WP_172952610.1 VirK/YbjX family protein -
CRN23_RS04505 931757..932410 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
CRN23_RS04510 932407..932598 - 192 WP_002911395.1 YebW family protein -
CRN23_RS04515 932696..932935 - 240 WP_002911393.1 YebV family protein -
CRN23_RS04520 933051..934484 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T86353 NZ_CP023913:929906-930008 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT86353 NZ_CP023913:c930015-929870 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References