Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2080708..2080853 Replicon chromosome
Accession NZ_CP023839
Organism Klebsiella pneumoniae strain 4/1-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2080744..2080846 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2080708..2080853 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRT36_RS10200 2075838..2077898 + 2061 WP_004151449.1 oligopeptidase B -
CRT36_RS10205 2077902..2078561 - 660 WP_002911407.1 exodeoxyribonuclease X -
CRT36_RS10210 2078640..2078870 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CRT36_RS10215 2078983..2079357 + 375 WP_039819395.1 CopC domain-containing protein YobA -
CRT36_RS10220 2079361..2080230 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
CRT36_RS10225 2080247..2080585 + 339 WP_002911404.1 YebY family protein -
- 2080708..2080853 - 146 - - Antitoxin
- 2080744..2080846 + 103 - - Toxin
CRT36_RS28500 2081222..2081365 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
CRT36_RS10235 2081470..2082438 - 969 WP_014907334.1 VirK/YbjX family protein -
CRT36_RS10240 2082595..2083248 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
CRT36_RS10245 2083245..2083436 - 192 WP_002911395.1 YebW family protein -
CRT36_RS10250 2083534..2083773 - 240 WP_002911393.1 YebV family protein -
CRT36_RS10255 2083889..2085322 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T86174 NZ_CP023839:2080744-2080846 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT86174 NZ_CP023839:c2080853-2080708 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References