Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2117889..2118160 Replicon chromosome
Accession NZ_CP023820
Organism Escherichia coli strain 7/2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2117927..2118030 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2117889..2118160 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CRT46_RS10400 2115046..2116485 + 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CRT46_RS10405 2116603..2116839 + 237 WP_001295499.1 DUF1480 family protein -
CRT46_RS10410 2116944..2117135 + 192 WP_001296140.1 YebW family protein -
CRT46_RS10415 2117136..2117792 - 657 WP_001520704.1 protein-serine/threonine phosphatase -
- 2117889..2118160 + 272 - - Antitoxin
- 2117927..2118030 - 104 - - Toxin
CRT46_RS10420 2118188..2118529 - 342 WP_001520705.1 YebY family protein -
CRT46_RS10425 2118542..2119414 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
CRT46_RS10430 2119418..2119792 - 375 WP_000204705.1 CopC domain-containing protein YobA -
CRT46_RS10435 2119931..2120161 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CRT46_RS10440 2120263..2120919 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
CRT46_RS10445 2120943..2121605 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T86076 NZ_CP023820:c2118030-2117927 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT86076 NZ_CP023820:2117889-2118160 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References