Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3026655..3027103 Replicon chromosome
Accession NZ_CP023741
Organism Sphingobium yanoikuyae strain S72

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A6768_RS13895 Protein ID WP_097384046.1
Coordinates 3026831..3027103 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A6768_RS13890 Protein ID WP_097385691.1
Coordinates 3026655..3026831 (+) Length 59 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6768_RS13875 3022375..3025290 + 2916 WP_097384043.1 excinuclease ABC subunit UvrA -
A6768_RS13880 3025395..3025832 + 438 WP_097384044.1 hypothetical protein -
A6768_RS13885 3025846..3026418 - 573 WP_097384045.1 hypothetical protein -
A6768_RS13890 3026655..3026831 + 177 WP_097385691.1 stability determinant Antitoxin
A6768_RS13895 3026831..3027103 + 273 WP_097384046.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A6768_RS13900 3027241..3028437 + 1197 WP_097384047.1 hypothetical protein -
A6768_RS13905 3028550..3028765 + 216 WP_037512246.1 cold-shock protein -
A6768_RS13910 3028841..3029443 - 603 WP_037491660.1 hypothetical protein -
A6768_RS13915 3029589..3029795 + 207 WP_097384048.1 hypothetical protein -
A6768_RS13920 3029990..3030358 + 369 WP_010336654.1 glycine zipper 2TM domain-containing protein -
A6768_RS13925 3030422..3031354 - 933 WP_097384049.1 FAD-binding protein -
A6768_RS13930 3031351..3032100 - 750 WP_097385692.1 electron transfer flavoprotein subunit beta/FixA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10354.92 Da        Isoelectric Point: 6.8782

>T85988 WP_097384046.1 NZ_CP023741:3026831-3027103 [Sphingobium yanoikuyae]
MLPLIWHVAALDDLERIVDFIEAQNPAAAERIGNAIRHVAERLPDHPYLYRSGRVPGTREALVTPNYVIVYRVTDIIEIL
AVRHTRQQYP

Download         Length: 273 bp

>T85988 NZ_CP023741:3026831-3027103 [Sphingobium yanoikuyae]
ATGCTACCGCTCATCTGGCATGTTGCGGCGCTGGATGATCTGGAACGCATCGTCGACTTCATAGAAGCGCAGAACCCCGC
CGCCGCAGAGCGCATCGGCAATGCCATCCGCCATGTCGCCGAGCGGCTGCCCGATCACCCCTATCTCTATCGTTCCGGCC
GCGTCCCCGGCACGCGGGAAGCACTGGTCACGCCCAACTATGTCATCGTCTATCGCGTGACCGACATCATCGAGATATTG
GCCGTCCGGCACACTCGCCAGCAATATCCCTGA

Antitoxin


Download         Length: 59 a.a.        Molecular weight: 6556.34 Da        Isoelectric Point: 4.4797

>AT85988 WP_097385691.1 NZ_CP023741:3026655-3026831 [Sphingobium yanoikuyae]
MTKLTPIESEFASTEEAEAYDAWFRATVEARMASDQPGIPHDEAMARMQAIIDRRKQG

Download         Length: 177 bp

>AT85988 NZ_CP023741:3026655-3026831 [Sphingobium yanoikuyae]
ATGACCAAGCTCACCCCCATCGAGTCCGAATTCGCTTCGACCGAAGAGGCCGAAGCCTATGACGCCTGGTTCCGCGCCAC
AGTCGAAGCCCGCATGGCGTCGGACCAGCCCGGCATCCCCCATGACGAGGCGATGGCGCGGATGCAGGCGATCATCGACC
GCCGCAAGCAAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References