85949

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4088345..4088490 Replicon chromosome
Accession NZ_CP023722
Organism Klebsiella pneumoniae strain TVGHCRE225

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4088352..4088454 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4088345..4088490 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO233_RS20820 4083877..4085310 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CO233_RS20825 4085426..4085665 + 240 WP_002911393.1 YebV family protein -
CO233_RS20830 4085763..4085954 + 192 WP_002911395.1 YebW family protein -
CO233_RS20835 4085951..4086604 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
CO233_RS20840 4086761..4087729 + 969 WP_004151446.1 VirK/YbjX family protein -
CO233_RS31720 4087834..4087977 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4088345..4088490 + 146 - - Antitoxin
- 4088352..4088454 - 103 - - Toxin
CO233_RS20850 4088613..4088951 - 339 WP_002911404.1 YebY family protein -
CO233_RS20855 4088968..4089837 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
CO233_RS20860 4089841..4090215 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CO233_RS20865 4090328..4090558 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CO233_RS20870 4090637..4091296 + 660 WP_002911407.1 exodeoxyribonuclease X -
CO233_RS20875 4091300..4093360 - 2061 WP_110437850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T85949 NZ_CP023722:c4088454-4088352 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT85949 NZ_CP023722:4088345-4088490 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References