Detailed information of TA system TA085934

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 36364..36903
• Replicon: plasmid unnamed1
• Accession: NZ_CP023712
• Organism: Rhodococcus ruber strain YC-YT1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: YT1_RS00220
• Protein ID: WP_119699163.1
• Coordinates: 36652..36903 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: YT1_RS00215
• Protein ID: WP_119699071.1
• Coordinates: 36364..36633 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
YT1_RS26980	32329..32499	-	171	WP_162919240.1	hypothetical protein	-
YT1_RS00190	32591..32854	+	264	WP_119699068.1	hypothetical protein	-
YT1_RS00195	33135..33455	+	321	WP_162919241.1	hypothetical protein	-
YT1_RS00200	33553..34014	-	462	WP_119699162.1	VOC family protein	-
YT1_RS26985	34314..34502	-	189	WP_162919242.1	hypothetical protein	-
YT1_RS00205	35046..35213	-	168	WP_208643836.1	hypothetical protein	-
YT1_RS00210	35494..36048	+	555	WP_119699070.1	hypothetical protein	-
YT1_RS00215	36364..36633	+	270	WP_119699071.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
YT1_RS00220	36652..36903	+	252	WP_119699163.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
YT1_RS00225	37101..37631	-	531	WP_119699072.1	hypothetical protein	-
YT1_RS00230	37679..38089	-	411	WP_119699073.1	hypothetical protein	-
YT1_RS00235	37995..39349	+	1355	Protein_46	3' terminal RNA ribose 2'-O-methyltransferase Hen1	-
YT1_RS00240	39346..41856	+	2511	WP_119699074.1	polynucleotide kinase-phosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..159746	159746

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (1-81)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9586.96 Da
• Isoelectric Point: 9.9806

>T85934 WP_119699163.1 NZ_CP023712:36652-36903 [Rhodococcus ruber]
IRVTTRAERDLQRLPEKIATACVEFIFGALAENPRRVGKPLRADLEGLYSARRGDYRVIYGVVDDARTVEVVHIDRRSDV
YRR

Nucleotide

• Length: 252 bp

>T85934 NZ_CP023712:36652-36903 [Rhodococcus ruber]
ATCCGGGTCACGACTCGAGCGGAACGCGACCTGCAGCGGTTGCCGGAGAAGATCGCCACGGCCTGCGTCGAGTTCATCTT
CGGCGCGCTTGCCGAGAATCCGCGGCGGGTAGGCAAGCCACTCCGCGCCGACCTCGAGGGCCTCTACTCCGCTCGCCGAG
GTGACTACCGCGTGATCTACGGCGTCGTCGACGACGCCCGCACCGTGGAGGTCGTGCACATAGATCGCCGAAGCGATGTC
TACAGACGGTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9532.67 Da
• Isoelectric Point: 4.6388

>AT85934 WP_119699071.1 NZ_CP023712:36364-36633 [Rhodococcus ruber]
MTAVPLGDARDRLSEYVSEVERTHQRLTITRHGRPAAVLISADDLAALEETLEILGTPGAVEAIGEGLADAKSGRFADNE
QLKSRYGIA

Nucleotide

• Length: 270 bp

>AT85934 NZ_CP023712:36364-36633 [Rhodococcus ruber]
ATGACCGCTGTGCCTCTGGGCGACGCGCGAGATCGGCTCTCGGAGTACGTCTCGGAGGTCGAACGCACCCACCAACGCCT
CACCATCACGCGCCACGGCCGTCCGGCCGCGGTCCTCATCTCCGCCGACGATCTTGCCGCCCTGGAGGAGACCCTGGAAA
TCCTCGGCACCCCGGGCGCTGTCGAGGCCATCGGGGAGGGTCTCGCCGACGCCAAGTCGGGTCGCTTCGCCGACAACGAA
CAACTCAAGTCCCGTTACGGGATCGCCTGA