Detailed information of TA system TA085902

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 2116904..2118459
• Replicon: chromosome
• Accession: NZ_CP023687
• Organism: Acidovorax citrulli strain KACC17005

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: CQB05_RS09465
• Protein ID: WP_011796138.1
• Coordinates: 2116904..2118148 (+)
• Length: 415 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: A1TRP1
• Locus tag: CQB05_RS09470
• Protein ID: WP_011796139.1
• Coordinates: 2118163..2118459 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CQB05_RS09450	2112798..2113136	-	339	WP_011796135.1	hypothetical protein	-
CQB05_RS09455	2113452..2114414	-	963	WP_011796136.1	FHA domain-containing protein	-
CQB05_RS09460	2114440..2116644	-	2205	WP_041828059.1	TOMM precursor leader peptide-binding protein	-
CQB05_RS09465	2116904..2118148	+	1245	WP_011796138.1	zeta toxin family protein	Toxin
CQB05_RS09470	2118163..2118459	+	297	WP_011796139.1	hypothetical protein	Antitoxin
CQB05_RS09475	2118618..2119481	-	864	WP_011796140.1	class I SAM-dependent methyltransferase	-
CQB05_RS09480	2119482..2120279	-	798	WP_011796141.1	BMA_0021/BMA_0022 family TOMM bacteriocin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (145-284)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 415 a.a.
• Molecular weight: 44326.94 Da
• Isoelectric Point: 8.6793

>T85902 WP_011796138.1 NZ_CP023687:2116904-2118148 [Acidovorax citrulli]
MTDRLSRRNSANSTPRPVTSNAASISRHETPPRPTSRPVHALPAGFPAPSQRSRSSSPSRVRASLPAKVPETSGNRPAIR
LPAAPRGSDEIFGLGELPPPGQSRWDYLAHPQNWRPERRQLHDRLIGDAKTAAQDFAEVIERGGHPPTLFALRGNTAAGK
TRMATQTIPVLANALKESGGAGCINPDIFKRSLAETPEGAKLTSAQVHAESCILADRLEDELRLQKTASGAAISMLVDKR
LAGAHEIDAYIKLAQETGRKIELCDIDAPLEQSLMGVLQRKPEGDAPRPPYVAVANGFSAVRGHRLDVIDKFLSNPTLGS
YHLFGTTGNGSKAMVASVVNGELSIHDPQLYEAITDPQGARAGDSGDQIIDAALIDRLTKGIDDPARAMDARTALERYAG
MTWSDALAAHSSLT

Nucleotide

• Length: 1245 bp

>T85902 NZ_CP023687:2116904-2118148 [Acidovorax citrulli]
ATGACAGACAGACTCAGCCGGCGAAATTCAGCGAATTCAACGCCCCGGCCCGTGACCAGCAACGCCGCTTCGATCAGCCG
GCATGAAACGCCACCGCGCCCGACCTCCCGTCCGGTGCATGCGCTGCCAGCCGGCTTCCCGGCACCATCGCAGAGATCGC
GCAGTTCATCGCCTTCACGGGTCAGGGCCTCACTGCCGGCAAAAGTGCCGGAGACATCGGGCAACAGGCCTGCGATCCGT
TTGCCGGCCGCACCCAGGGGGTCGGACGAGATCTTCGGCCTGGGGGAACTCCCTCCTCCTGGCCAGTCCCGATGGGACTA
TTTGGCCCATCCTCAAAACTGGCGCCCCGAGCGGCGTCAATTGCATGACCGGCTGATCGGCGATGCGAAAACTGCAGCCC
AGGATTTCGCCGAGGTGATCGAGCGCGGTGGCCACCCACCGACATTGTTCGCGTTGCGAGGCAATACGGCTGCGGGAAAG
ACACGCATGGCGACACAAACCATCCCCGTACTCGCCAATGCCCTCAAGGAGAGTGGCGGCGCCGGCTGTATTAATCCCGA
CATCTTCAAACGTTCGCTCGCAGAAACTCCAGAGGGAGCAAAACTTACCTCGGCGCAGGTACACGCCGAGTCGTGCATCC
TCGCTGACCGGCTTGAAGACGAACTCCGATTGCAGAAGACCGCGAGCGGCGCGGCGATCAGCATGCTGGTCGATAAGCGA
CTGGCTGGAGCGCACGAAATCGACGCGTACATCAAGCTGGCTCAGGAGACCGGTCGCAAAATCGAGTTGTGCGATATTGA
TGCTCCACTCGAGCAGTCACTCATGGGCGTGCTGCAGCGCAAGCCCGAAGGTGACGCCCCCCGGCCACCCTACGTTGCGG
TTGCCAACGGATTCTCGGCGGTTCGCGGGCACCGGCTCGATGTCATCGACAAGTTTCTCTCGAACCCGACCTTGGGGAGC
TATCATCTATTCGGCACTACCGGGAATGGCAGCAAGGCGATGGTTGCCAGCGTCGTCAACGGCGAACTGAGCATTCATGA
CCCTCAGTTATACGAGGCCATTACAGATCCCCAAGGTGCCCGGGCAGGCGATAGCGGCGATCAGATCATTGACGCTGCGC
TGATCGACCGGCTGACCAAAGGTATAGACGACCCAGCGCGAGCCATGGATGCCCGCACCGCATTGGAGCGGTACGCGGGC
ATGACGTGGTCGGACGCTCTGGCCGCCCATAGTTCACTGACTTGA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11106.62 Da
• Isoelectric Point: 6.9795

>AT85902 WP_011796139.1 NZ_CP023687:2118163-2118459 [Acidovorax citrulli]
MTGLKGADALDFHKKLKERNAALRNAELNAAKELADKNGKEPFDLVKLERLCDTSQAGRLVEGTERQAMYEYMYYVEYKN
VGTLQDFARVVTTLASWS

Nucleotide

• Length: 297 bp

>AT85902 NZ_CP023687:2118163-2118459 [Acidovorax citrulli]
ATGACAGGCCTGAAAGGCGCAGATGCGCTCGACTTCCATAAGAAACTCAAGGAACGCAATGCTGCTTTACGCAATGCGGA
GTTGAACGCGGCGAAGGAACTGGCCGACAAAAATGGCAAGGAGCCTTTTGATCTCGTGAAACTGGAGAGGCTTTGCGATA
CCAGTCAAGCAGGCCGCCTTGTTGAAGGGACCGAACGGCAAGCCATGTACGAATACATGTACTACGTCGAGTACAAGAAT
GTTGGCACGTTGCAGGATTTCGCCCGGGTGGTGACAACGCTCGCGTCCTGGTCTTAA

Structures

Antitoxin

• AlphaFold DB: A1TRP1