Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) omega-epsilon-zeta/-
Location 2116904..2118459 Replicon chromosome
Accession NZ_CP023687
Organism Acidovorax citrulli strain KACC17005

Toxin (Protein)


Gene name avrRxo1 Uniprot ID -
Locus tag CQB05_RS09465 Protein ID WP_011796138.1
Coordinates 2116904..2118148 (+) Length 415 a.a.

Antitoxin (Protein)


Gene name arc1 Uniprot ID A1TRP1
Locus tag CQB05_RS09470 Protein ID WP_011796139.1
Coordinates 2118163..2118459 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CQB05_RS09450 2112798..2113136 - 339 WP_011796135.1 hypothetical protein -
CQB05_RS09455 2113452..2114414 - 963 WP_011796136.1 FHA domain-containing protein -
CQB05_RS09460 2114440..2116644 - 2205 WP_041828059.1 TOMM precursor leader peptide-binding protein -
CQB05_RS09465 2116904..2118148 + 1245 WP_011796138.1 zeta toxin family protein Toxin
CQB05_RS09470 2118163..2118459 + 297 WP_011796139.1 hypothetical protein Antitoxin
CQB05_RS09475 2118618..2119481 - 864 WP_011796140.1 class I SAM-dependent methyltransferase -
CQB05_RS09480 2119482..2120279 - 798 WP_011796141.1 BMA_0021/BMA_0022 family TOMM bacteriocin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(145-284)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 415 a.a.        Molecular weight: 44326.94 Da        Isoelectric Point: 8.6793

>T85902 WP_011796138.1 NZ_CP023687:2116904-2118148 [Acidovorax citrulli]
MTDRLSRRNSANSTPRPVTSNAASISRHETPPRPTSRPVHALPAGFPAPSQRSRSSSPSRVRASLPAKVPETSGNRPAIR
LPAAPRGSDEIFGLGELPPPGQSRWDYLAHPQNWRPERRQLHDRLIGDAKTAAQDFAEVIERGGHPPTLFALRGNTAAGK
TRMATQTIPVLANALKESGGAGCINPDIFKRSLAETPEGAKLTSAQVHAESCILADRLEDELRLQKTASGAAISMLVDKR
LAGAHEIDAYIKLAQETGRKIELCDIDAPLEQSLMGVLQRKPEGDAPRPPYVAVANGFSAVRGHRLDVIDKFLSNPTLGS
YHLFGTTGNGSKAMVASVVNGELSIHDPQLYEAITDPQGARAGDSGDQIIDAALIDRLTKGIDDPARAMDARTALERYAG
MTWSDALAAHSSLT

Download         Length: 1245 bp

>T85902 NZ_CP023687:2116904-2118148 [Acidovorax citrulli]
ATGACAGACAGACTCAGCCGGCGAAATTCAGCGAATTCAACGCCCCGGCCCGTGACCAGCAACGCCGCTTCGATCAGCCG
GCATGAAACGCCACCGCGCCCGACCTCCCGTCCGGTGCATGCGCTGCCAGCCGGCTTCCCGGCACCATCGCAGAGATCGC
GCAGTTCATCGCCTTCACGGGTCAGGGCCTCACTGCCGGCAAAAGTGCCGGAGACATCGGGCAACAGGCCTGCGATCCGT
TTGCCGGCCGCACCCAGGGGGTCGGACGAGATCTTCGGCCTGGGGGAACTCCCTCCTCCTGGCCAGTCCCGATGGGACTA
TTTGGCCCATCCTCAAAACTGGCGCCCCGAGCGGCGTCAATTGCATGACCGGCTGATCGGCGATGCGAAAACTGCAGCCC
AGGATTTCGCCGAGGTGATCGAGCGCGGTGGCCACCCACCGACATTGTTCGCGTTGCGAGGCAATACGGCTGCGGGAAAG
ACACGCATGGCGACACAAACCATCCCCGTACTCGCCAATGCCCTCAAGGAGAGTGGCGGCGCCGGCTGTATTAATCCCGA
CATCTTCAAACGTTCGCTCGCAGAAACTCCAGAGGGAGCAAAACTTACCTCGGCGCAGGTACACGCCGAGTCGTGCATCC
TCGCTGACCGGCTTGAAGACGAACTCCGATTGCAGAAGACCGCGAGCGGCGCGGCGATCAGCATGCTGGTCGATAAGCGA
CTGGCTGGAGCGCACGAAATCGACGCGTACATCAAGCTGGCTCAGGAGACCGGTCGCAAAATCGAGTTGTGCGATATTGA
TGCTCCACTCGAGCAGTCACTCATGGGCGTGCTGCAGCGCAAGCCCGAAGGTGACGCCCCCCGGCCACCCTACGTTGCGG
TTGCCAACGGATTCTCGGCGGTTCGCGGGCACCGGCTCGATGTCATCGACAAGTTTCTCTCGAACCCGACCTTGGGGAGC
TATCATCTATTCGGCACTACCGGGAATGGCAGCAAGGCGATGGTTGCCAGCGTCGTCAACGGCGAACTGAGCATTCATGA
CCCTCAGTTATACGAGGCCATTACAGATCCCCAAGGTGCCCGGGCAGGCGATAGCGGCGATCAGATCATTGACGCTGCGC
TGATCGACCGGCTGACCAAAGGTATAGACGACCCAGCGCGAGCCATGGATGCCCGCACCGCATTGGAGCGGTACGCGGGC
ATGACGTGGTCGGACGCTCTGGCCGCCCATAGTTCACTGACTTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11106.62 Da        Isoelectric Point: 6.9795

>AT85902 WP_011796139.1 NZ_CP023687:2118163-2118459 [Acidovorax citrulli]
MTGLKGADALDFHKKLKERNAALRNAELNAAKELADKNGKEPFDLVKLERLCDTSQAGRLVEGTERQAMYEYMYYVEYKN
VGTLQDFARVVTTLASWS

Download         Length: 297 bp

>AT85902 NZ_CP023687:2118163-2118459 [Acidovorax citrulli]
ATGACAGGCCTGAAAGGCGCAGATGCGCTCGACTTCCATAAGAAACTCAAGGAACGCAATGCTGCTTTACGCAATGCGGA
GTTGAACGCGGCGAAGGAACTGGCCGACAAAAATGGCAAGGAGCCTTTTGATCTCGTGAAACTGGAGAGGCTTTGCGATA
CCAGTCAAGCAGGCCGCCTTGTTGAAGGGACCGAACGGCAAGCCATGTACGAATACATGTACTACGTCGAGTACAAGAAT
GTTGGCACGTTGCAGGATTTCGCCCGGGTGGTGACAACGCTCGCGTCCTGGTCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A1TRP1

References