Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4649959..4650320 | Replicon | chromosome |
Accession | NZ_CP023662 | ||
Organism | Xanthomonas citri pv. citri strain Xcc49 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | M4UGA1 |
Locus tag | CPA10_RS21105 | Protein ID | WP_005914328.1 |
Coordinates | 4649959..4650093 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | H8FG64 |
Locus tag | CPA10_RS21110 | Protein ID | WP_003486606.1 |
Coordinates | 4650168..4650320 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CPA10_RS21085 | 4645097..4646788 | - | 1692 | WP_015471463.1 | M20/M25/M40 family metallo-hydrolase | - |
CPA10_RS21090 | 4646980..4648014 | - | 1035 | WP_011052671.1 | MBL fold metallo-hydrolase | - |
CPA10_RS21095 | 4648053..4649342 | - | 1290 | WP_015463705.1 | tryptophan--tRNA ligase | - |
CPA10_RS21100 | 4649523..4649732 | - | 210 | WP_003486601.1 | CsbD family protein | - |
CPA10_RS21105 | 4649959..4650093 | - | 135 | WP_005914328.1 | entericidin A/B family lipoprotein | Toxin |
CPA10_RS21110 | 4650168..4650320 | - | 153 | WP_003486606.1 | entericidin A/B family lipoprotein | Antitoxin |
CPA10_RS21115 | 4650427..4651350 | - | 924 | WP_005927745.1 | arginase | - |
CPA10_RS21120 | 4651671..4652123 | + | 453 | WP_003486611.1 | roadblock/LC7 domain-containing protein | - |
CPA10_RS21125 | 4652187..4652546 | + | 360 | WP_003486613.1 | hypothetical protein | - |
CPA10_RS21130 | 4652643..4653560 | + | 918 | WP_011052673.1 | hypothetical protein | - |
CPA10_RS21135 | 4653557..4654099 | + | 543 | WP_003486615.1 | GTPase | - |
CPA10_RS21145 | 4654537..4655220 | + | 684 | WP_011052674.1 | dTMP kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4459.32 Da Isoelectric Point: 9.3487
>T85843 WP_005914328.1 NZ_CP023662:c4650093-4649959 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK
Download Length: 135 bp
>T85843 NZ_CP023662:c4650093-4649959 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5122.07 Da Isoelectric Point: 8.7942
>AT85843 WP_003486606.1 NZ_CP023662:c4650320-4650168 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC
Download Length: 153 bp
>AT85843 NZ_CP023662:c4650320-4650168 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2W7U6 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A828YLX6 |