85838

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4658885..4659246 Replicon chromosome
Accession NZ_CP023661
Organism Xanthomonas citri pv. citri strain Xcc29-1

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag COR42_RS21135 Protein ID WP_005914328.1
Coordinates 4658885..4659019 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag COR42_RS21140 Protein ID WP_003486606.1
Coordinates 4659094..4659246 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COR42_RS21115 4654023..4655714 - 1692 WP_015471463.1 M20/M25/M40 family metallo-hydrolase -
COR42_RS21120 4655906..4656940 - 1035 WP_011052671.1 MBL fold metallo-hydrolase -
COR42_RS21125 4656979..4658268 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
COR42_RS21130 4658449..4658658 - 210 WP_003486601.1 CsbD family protein -
COR42_RS21135 4658885..4659019 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
COR42_RS21140 4659094..4659246 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
COR42_RS21145 4659353..4660276 - 924 WP_005927745.1 arginase -
COR42_RS21150 4660597..4661049 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
COR42_RS21155 4661113..4661472 + 360 WP_003486613.1 hypothetical protein -
COR42_RS21160 4661569..4662486 + 918 WP_011052673.1 hypothetical protein -
COR42_RS21165 4662483..4663025 + 543 WP_003486615.1 GTPase -
COR42_RS21175 4663463..4664146 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T85838 WP_005914328.1 NZ_CP023661:c4659019-4658885 [Xanthomonas citri pv. citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T85838 NZ_CP023661:c4659019-4658885 [Xanthomonas citri pv. citri]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT85838 WP_003486606.1 NZ_CP023661:c4659246-4659094 [Xanthomonas citri pv. citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT85838 NZ_CP023661:c4659246-4659094 [Xanthomonas citri pv. citri]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References