85828

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1226072..1226627 Replicon chromosome
Accession NZ_CP023657
Organism Acetobacter pomorum strain BDGP5

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag CPF11_RS05790 Protein ID WP_096884271.1
Coordinates 1226364..1226627 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag CPF11_RS05785 Protein ID WP_081461476.1
Coordinates 1226072..1226356 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPF11_RS05760 1221347..1222600 - 1254 WP_035351293.1 TIGR03862 family flavoprotein -
CPF11_RS05765 1222634..1223467 - 834 WP_006116860.1 tryptophan synthase subunit alpha -
CPF11_RS05770 1223464..1224783 - 1320 WP_006116859.1 tryptophan synthase subunit beta -
CPF11_RS05775 1225076..1225648 - 573 WP_096884270.1 site-specific integrase -
CPF11_RS05780 1225846..1226055 + 210 WP_035354356.1 hypothetical protein -
CPF11_RS05785 1226072..1226356 - 285 WP_081461476.1 BrnA antitoxin family protein Antitoxin
CPF11_RS05790 1226364..1226627 - 264 WP_096884271.1 BrnT family toxin Toxin
CPF11_RS05795 1226993..1228183 + 1191 WP_170315325.1 magnesium transporter CorA family protein -
CPF11_RS05800 1228185..1228718 + 534 WP_035351199.1 hypothetical protein -
CPF11_RS05805 1228954..1230252 + 1299 WP_035351198.1 transcription termination factor Rho -
CPF11_RS05810 1230317..1230610 - 294 WP_003623789.1 sulfurtransferase TusA family protein -
CPF11_RS05815 1230770..1231258 + 489 WP_006116856.1 transcriptional repressor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-79)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(19-90)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10048.48 Da        Isoelectric Point: 9.7308

>T85828 WP_096884271.1 NZ_CP023657:c1226627-1226364 [Acetobacter pomorum]
MRYDWDEAKRQSNSAKHGVDFADAEDFEWDVAFVMTSRSANEPRLVAIAPINLRLHVLVFSIETRIVRIISLRKANKREA
KLYAAQT

Download         Length: 264 bp

>T85828 NZ_CP023657:c1226627-1226364 [Acetobacter pomorum]
ATGAGATACGATTGGGACGAAGCAAAGCGTCAAAGTAACAGCGCCAAGCATGGCGTTGATTTTGCTGATGCTGAAGACTT
CGAATGGGATGTGGCTTTTGTCATGACAAGTCGTAGCGCAAACGAGCCCCGCCTTGTTGCTATTGCCCCAATCAATCTCC
GCCTGCATGTGCTGGTTTTCAGCATTGAAACACGCATTGTCCGCATCATCAGCCTACGAAAGGCCAACAAACGGGAGGCA
AAGCTTTATGCCGCGCAAACCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10284.66 Da        Isoelectric Point: 4.7435

>AT85828 WP_081461476.1 NZ_CP023657:c1226356-1226072 [Acetobacter pomorum]
MPTDEEDALINQGILQDADNPELTDQDFLNAKPASVAVPALAAQRRVRGPQKAPTKKLVSIRLDPDLIDRLKQDGPGWQG
RVNDMLRQAIGLTS

Download         Length: 285 bp

>AT85828 NZ_CP023657:c1226356-1226072 [Acetobacter pomorum]
ATGCCTACGGATGAAGAAGATGCCCTGATCAATCAGGGCATCTTGCAAGATGCAGATAACCCCGAGCTAACGGATCAAGA
TTTTCTCAATGCCAAACCTGCATCTGTAGCTGTGCCAGCATTAGCAGCACAGCGTAGAGTAAGAGGGCCACAAAAAGCTC
CCACAAAGAAGCTTGTATCGATTCGTCTTGACCCCGATTTGATTGACCGGCTGAAACAGGACGGCCCTGGTTGGCAAGGG
CGCGTTAACGATATGCTACGGCAAGCCATAGGCCTAACCAGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References