Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1678178..1679589 Replicon chromosome
Accession NZ_CP023641
Organism Pseudomonas mendocina strain MAE1-K

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag CO724_RS07995 Protein ID WP_096825807.1
Coordinates 1678178..1678747 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag CO724_RS08000 Protein ID WP_003246035.1
Coordinates 1678750..1679589 (+) Length 280 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO724_RS07985 1673593..1674447 + 855 WP_096825805.1 MerR family transcriptional regulator -
CO724_RS07990 1674489..1677977 - 3489 WP_096825806.1 hybrid sensor histidine kinase/response regulator -
CO724_RS07995 1678178..1678747 + 570 WP_096825807.1 GNAT family N-acetyltransferase Toxin
CO724_RS08000 1678750..1679589 + 840 WP_003246035.1 AraC family transcriptional regulator Antitoxin
CO724_RS08005 1679665..1681002 - 1338 WP_096825808.1 peptidase -
CO724_RS08010 1681193..1681765 + 573 WP_003246031.1 LemA family protein -
CO724_RS08015 1681767..1682672 + 906 WP_096825809.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21341.51 Da        Isoelectric Point: 9.8676

>T85798 WP_096825807.1 NZ_CP023641:1678178-1678747 [Pseudomonas mendocina]
MFKPQLVTLQRGALRLEPLADADIPALVALAEANRDELLYMSGTQRLDWYRSALAELREQRALPFAIRLGEQLVGTTRFG
DFMNSLPACEIGWTWLDRAQHGSGLNASIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAAREGLLRNHRRLAD
GRLDHTVLYSITDQEWPQVRAALEARFGG

Download         Length: 570 bp

>T85798 NZ_CP023641:1678178-1678747 [Pseudomonas mendocina]
ATGTTCAAACCGCAATTGGTCACGCTGCAGCGAGGAGCCTTGCGCCTGGAGCCACTGGCCGATGCCGATATCCCGGCCCT
GGTCGCGCTGGCCGAGGCCAATCGTGACGAGCTGCTGTACATGAGCGGTACCCAGCGTCTGGACTGGTATCGCAGCGCAC
TGGCCGAACTGCGCGAGCAACGCGCGCTGCCATTCGCCATCCGTCTCGGCGAGCAATTGGTCGGCACCACTCGCTTCGGC
GATTTCATGAACAGCCTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGATCGCGCCCAGCATGGCAGCGGGCTGAACGC
CAGCATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACTGGGGCATGGTCCGTGTGCAGCTGAAAACCGCCGCCAGCA
ACCTGCGCTCGCAACGCGCCATCGAGAAGCTGGGCGCCGCCCGCGAGGGCCTGCTGCGTAACCATCGCCGCCTGGCCGAC
GGCCGTCTCGACCACACGGTGCTGTACAGCATCACCGATCAGGAATGGCCGCAGGTGCGCGCCGCCCTGGAAGCGCGCTT
CGGCGGCTGA

Antitoxin


Download         Length: 280 a.a.        Molecular weight: 30956.10 Da        Isoelectric Point: 7.7422

>AT85798 WP_003246035.1 NZ_CP023641:1678750-1679589 [Pseudomonas mendocina]
MQPLTGSERARFSASDDLHGLELLSARFVEHRFAPHVHDGHVIAVLEAGAERYRYRGVDHLAGAGSIALLNPDEVHTGSK
GVEQGWQYRVFYPQPGTFEALLAELESPPAAPPMFHDSVHHDPLLASRLSALHRLLEDPHSEALQRQTLWREAMLELLQR
YARLPAPRGVGQEPRAVALAKELLASQLSEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLRQRRLEQARTLLRSGC
SALSVAMQLGFADQSHLSRQFKQTYGVSPGEYRSAVARG

Download         Length: 840 bp

>AT85798 NZ_CP023641:1678750-1679589 [Pseudomonas mendocina]
ATGCAGCCACTGACGGGAAGCGAACGCGCGCGGTTCAGCGCCAGCGACGATCTGCACGGCTTGGAGCTGTTGTCCGCACG
CTTTGTCGAACACCGTTTCGCCCCGCACGTGCACGACGGCCATGTGATCGCCGTGCTCGAAGCTGGTGCTGAGCGCTATC
GCTATCGCGGTGTCGATCACCTGGCGGGCGCCGGCAGCATCGCCTTGCTCAATCCGGACGAGGTGCATACCGGTTCCAAA
GGGGTCGAGCAAGGCTGGCAGTACCGGGTGTTCTACCCGCAGCCCGGTACTTTCGAGGCGCTGCTGGCCGAACTCGAGTC
GCCACCGGCTGCACCGCCCATGTTCCACGACAGCGTGCACCATGATCCGCTCCTGGCGTCGCGGCTGAGTGCGCTGCACC
GTCTGCTGGAGGATCCGCACAGCGAGGCGCTGCAACGTCAGACCCTGTGGCGCGAGGCGATGCTCGAGCTGCTGCAGCGT
TACGCGCGCCTGCCGGCGCCGCGTGGCGTCGGCCAGGAACCGCGGGCGGTGGCGTTGGCCAAGGAGCTGCTTGCCAGCCA
GCTGAGCGAGCCGCCATCGCTGGAAGAGCTGGCGGCAGCGGTCAATCTCTCACCCTTTCACTTCGCCCGGGTATTCCGCC
GGGCCACCGGTCTGCCACCGCATGCCTGGCTCAGGCAGCGCCGTCTGGAGCAGGCGCGGACGCTGCTCAGAAGTGGCTGC
TCGGCGCTCAGCGTCGCCATGCAGCTGGGGTTTGCCGACCAGAGCCATCTGTCGCGGCAGTTCAAGCAGACCTATGGCGT
CAGCCCCGGTGAATACCGCAGCGCGGTGGCGCGAGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References