Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2743185..2743388 Replicon chromosome
Accession NZ_CP023569
Organism Enterobacter hormaechei strain BW

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2743192..2743295 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2743185..2743388 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPT31_RS12990 2738336..2738764 + 429 WP_121926622.1 regulator -
CPT31_RS12995 2738761..2738913 + 153 WP_049125852.1 DUF1317 family protein -
CPT31_RS13000 2738910..2739569 + 660 WP_161503857.1 DNA methyltransferase -
CPT31_RS13005 2739566..2739784 + 219 WP_161503858.1 hypothetical protein -
CPT31_RS13010 2739781..2740296 + 516 WP_161503859.1 HNH endonuclease -
CPT31_RS13015 2740280..2740597 + 318 WP_161503860.1 hypothetical protein -
CPT31_RS13020 2740594..2740785 + 192 WP_161503861.1 DUF1382 family protein -
CPT31_RS13025 2740877..2741089 + 213 WP_161503862.1 TraR/DksA family transcriptional regulator -
CPT31_RS13030 2741146..2741667 + 522 WP_049125635.1 hypothetical protein -
CPT31_RS13035 2741788..2742060 + 273 WP_023300430.1 hypothetical protein -
CPT31_RS13040 2742029..2743114 + 1086 WP_161503863.1 phage integrase Arm DNA-binding domain-containing protein -
- 2743185..2743388 + 204 - - Antitoxin
- 2743192..2743295 - 104 - - Toxin
CPT31_RS13045 2743437..2743775 - 339 WP_003859787.1 YebY family protein -
CPT31_RS13050 2743792..2744661 - 870 WP_045341273.1 copper homeostasis membrane protein CopD -
CPT31_RS13055 2744663..2745034 - 372 WP_017384342.1 CopC domain-containing protein YobA -
CPT31_RS13060 2745172..2745402 + 231 WP_003859784.1 DNA polymerase III subunit theta -
CPT31_RS13065 2745514..2746164 + 651 WP_045341276.1 carbon-nitrogen hydrolase family protein -
CPT31_RS13070 2746189..2746851 + 663 WP_039270549.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2679885..2749634 69749


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T81649 NZ_CP023569:c2743295-2743192 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT81649 NZ_CP023569:2743185-2743388 [Enterobacter hormaechei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References