Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2723519..2723790 | Replicon | chromosome |
| Accession | NZ_CP023541 | ||
| Organism | Escherichia coli O104:H21 str. CFSAN002236 strain ATCC BAA-178 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2723557..2723660 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2723519..2723790 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CR208_RS13200 | 2720676..2722115 | + | 1440 | WP_000057022.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| CR208_RS13205 | 2722233..2722469 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| CR208_RS13210 | 2722574..2722765 | + | 192 | WP_001296140.1 | YebW family protein | - |
| CR208_RS13215 | 2722766..2723422 | - | 657 | WP_000812712.1 | protein-serine/threonine phosphatase | - |
| - | 2723519..2723790 | + | 272 | - | - | Antitoxin |
| - | 2723557..2723660 | - | 104 | - | - | Toxin |
| CR208_RS13220 | 2723818..2724159 | - | 342 | WP_000976472.1 | YebY family protein | - |
| CR208_RS13225 | 2724172..2725044 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| CR208_RS13230 | 2725048..2725422 | - | 375 | WP_000204700.1 | CopC domain-containing protein YobA | - |
| CR208_RS13235 | 2725561..2725791 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| CR208_RS13240 | 2725893..2726549 | + | 657 | Protein_2547 | carbon-nitrogen hydrolase family protein | - |
| CR208_RS13245 | 2726573..2727235 | + | 663 | WP_021292759.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T81590 NZ_CP023541:c2723660-2723557 [Escherichia coli O104:H21 str. CFSAN002236]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT81590 NZ_CP023541:2723519-2723790 [Escherichia coli O104:H21 str. CFSAN002236]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
