Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-HipB |
Location | 1179248..1180807 | Replicon | chromosome |
Accession | NZ_CP023529 | ||
Organism | Lelliottia amnigena strain FDAARGOS_395 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | A0A3S5XQH7 |
Locus tag | CO697_RS05820 | Protein ID | WP_059178935.1 |
Coordinates | 1179248..1180555 (-) | Length | 436 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | A0A3S5XQW5 |
Locus tag | CO697_RS05825 | Protein ID | WP_012017425.1 |
Coordinates | 1180556..1180807 (-) | Length | 84 a.a. |
Genomic Context
Location: 1174757..1175104 (348 bp)
Type: Others
Protein ID: WP_096759582.1
Type: Others
Protein ID: WP_096759582.1
Location: 1175468..1175755 (288 bp)
Type: Others
Protein ID: WP_059178932.1
Type: Others
Protein ID: WP_059178932.1
Location: 1175763..1177070 (1308 bp)
Type: Others
Protein ID: WP_174521007.1
Type: Others
Protein ID: WP_174521007.1
Location: 1181453..1182661 (1209 bp)
Type: Others
Protein ID: WP_059178937.1
Type: Others
Protein ID: WP_059178937.1
Location: 1184263..1185225 (963 bp)
Type: Others
Protein ID: WP_059178939.1
Type: Others
Protein ID: WP_059178939.1
Location: 1177083..1177844 (762 bp)
Type: Others
Protein ID: WP_059178933.1
Type: Others
Protein ID: WP_059178933.1
Location: 1177887..1179107 (1221 bp)
Type: Others
Protein ID: WP_059178934.1
Type: Others
Protein ID: WP_059178934.1
Location: 1179248..1180555 (1308 bp)
Type: Toxin
Protein ID: WP_059178935.1
Type: Toxin
Protein ID: WP_059178935.1
Location: 1180556..1180807 (252 bp)
Type: Antitoxin
Protein ID: WP_012017425.1
Type: Antitoxin
Protein ID: WP_012017425.1
Location: 1180895..1181359 (465 bp)
Type: Others
Protein ID: WP_059178936.1
Type: Others
Protein ID: WP_059178936.1
Location: 1182594..1184111 (1518 bp)
Type: Others
Protein ID: WP_059178938.1
Type: Others
Protein ID: WP_059178938.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CO697_RS05795 | 1174757..1175104 | + | 348 | WP_096759582.1 | hypothetical protein | - |
CO697_RS05800 | 1175468..1175755 | + | 288 | WP_059178932.1 | VF530 family protein | - |
CO697_RS05805 | 1175763..1177070 | + | 1308 | WP_174521007.1 | glycoside hydrolase family 10 protein | - |
CO697_RS05810 | 1177083..1177844 | - | 762 | WP_059178933.1 | thiol:disulfide interchange protein DsbG | - |
CO697_RS05815 | 1177887..1179107 | - | 1221 | WP_059178934.1 | diguanylate phosphodiesterase | - |
CO697_RS05820 | 1179248..1180555 | - | 1308 | WP_059178935.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
CO697_RS05825 | 1180556..1180807 | - | 252 | WP_012017425.1 | helix-turn-helix domain-containing protein | Antitoxin |
CO697_RS05830 | 1180895..1181359 | - | 465 | WP_059178936.1 | helix-turn-helix transcriptional regulator | - |
CO697_RS05835 | 1181453..1182661 | + | 1209 | WP_059178937.1 | MFS transporter | - |
CO697_RS05840 | 1182594..1184111 | - | 1518 | WP_059178938.1 | alpha/beta hydrolase | - |
CO697_RS05845 | 1184263..1185225 | + | 963 | WP_059178939.1 | mannuronate-specific alginate lyase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 436 a.a. Molecular weight: 49182.29 Da Isoelectric Point: 8.6915
>T81502 WP_059178935.1 NZ_CP023529:c1180555-1179248 [Lelliottia amnigena]
MKTSKLTVAMNGTVVGTLYRNGKGAMSWQYAQTWLDTPGARVISQSLPLTPRRQEGEVVYNFFSNLLPDSQAIISRMQTR
FKIPTDHPFDLLASVGRDCVGAIQLYPENSEIPPVTHMQATPLSDNEIAALLEGYRNAPLGMNDDQDFRISIAGAQEKTA
LLWHQNRWQRPNGSTPTSHIFKLPIGKIEQNNIDLSESCENEWLCLRLAREFGFSVAEATLATYADKKVLIVERFDRKWS
RDGKWLMRLPQEDMCQALGYSPALKYESHGGPGIAEIMTLLLGSRRSNQDRETFFRTQIFYWLTGAIDGHAKNYSVFIEP
DSAYVMTPLYDILSAYPVFGPKGISAQKAKMAMALQGKNRQYHWAQIQPRHFPATAERVGFSAIRAKKMMIEMGNATNEI
IERVRQSLPIDFPTHISEAIFNGMAKQAERLIRLE
MKTSKLTVAMNGTVVGTLYRNGKGAMSWQYAQTWLDTPGARVISQSLPLTPRRQEGEVVYNFFSNLLPDSQAIISRMQTR
FKIPTDHPFDLLASVGRDCVGAIQLYPENSEIPPVTHMQATPLSDNEIAALLEGYRNAPLGMNDDQDFRISIAGAQEKTA
LLWHQNRWQRPNGSTPTSHIFKLPIGKIEQNNIDLSESCENEWLCLRLAREFGFSVAEATLATYADKKVLIVERFDRKWS
RDGKWLMRLPQEDMCQALGYSPALKYESHGGPGIAEIMTLLLGSRRSNQDRETFFRTQIFYWLTGAIDGHAKNYSVFIEP
DSAYVMTPLYDILSAYPVFGPKGISAQKAKMAMALQGKNRQYHWAQIQPRHFPATAERVGFSAIRAKKMMIEMGNATNEI
IERVRQSLPIDFPTHISEAIFNGMAKQAERLIRLE
Download Length: 1308 bp
>T81502 NZ_CP023529:c1180555-1179248 [Lelliottia amnigena]
ATGAAAACCAGTAAGCTGACCGTTGCGATGAACGGTACGGTTGTCGGCACGCTGTATCGTAATGGAAAAGGGGCAATGTC
CTGGCAATATGCGCAGACATGGCTCGACACGCCGGGCGCGCGCGTGATTTCACAGTCGCTACCGTTAACGCCGCGTCGTC
AGGAAGGCGAGGTGGTGTATAACTTCTTTAGTAATTTGCTGCCTGACTCGCAGGCGATTATCTCGCGTATGCAAACGCGC
TTTAAAATCCCCACGGATCATCCCTTCGATTTGCTGGCAAGCGTTGGCCGCGACTGTGTTGGGGCAATCCAGCTCTACCC
GGAAAACAGTGAAATACCCCCTGTGACGCACATGCAGGCCACGCCGCTTTCCGATAACGAGATTGCGGCACTGCTGGAAG
GGTATCGTAATGCGCCATTGGGGATGAATGACGACCAGGATTTCAGGATTTCCATTGCAGGTGCGCAGGAAAAAACGGCA
CTGCTCTGGCATCAGAACCGCTGGCAACGCCCCAACGGCAGCACGCCCACCAGCCATATTTTCAAACTGCCCATCGGTAA
AATTGAGCAGAACAATATCGATCTGAGTGAAAGCTGCGAGAACGAATGGCTGTGTCTGCGCCTTGCCCGTGAATTCGGTT
TTTCGGTCGCCGAGGCAACGTTAGCAACCTATGCCGACAAAAAAGTGCTGATTGTTGAGCGTTTTGATCGTAAATGGTCA
CGAGACGGAAAGTGGCTGATGCGACTCCCGCAAGAAGATATGTGTCAGGCTCTCGGGTATTCACCGGCGCTGAAATATGA
ATCTCACGGCGGCCCCGGCATCGCCGAAATCATGACCTTGCTGTTGGGATCGCGCCGCTCAAACCAGGATCGCGAAACGT
TTTTCCGCACTCAGATATTTTACTGGCTGACAGGCGCGATCGATGGCCACGCAAAAAATTACAGTGTGTTTATCGAACCC
GATTCGGCGTACGTTATGACGCCGCTATACGATATTTTGTCAGCCTATCCGGTCTTCGGGCCAAAAGGAATTTCCGCACA
AAAAGCGAAAATGGCCATGGCGTTGCAGGGCAAAAACCGGCAATACCACTGGGCTCAGATTCAACCACGCCATTTCCCGG
CTACGGCTGAACGCGTTGGTTTTTCAGCTATACGCGCAAAAAAGATGATGATCGAAATGGGAAATGCGACAAATGAGATT
ATCGAGCGGGTACGTCAGTCGTTACCGATTGATTTCCCGACACATATCAGCGAAGCGATTTTTAACGGGATGGCGAAGCA
AGCTGAAAGGCTAATACGTTTAGAATAA
ATGAAAACCAGTAAGCTGACCGTTGCGATGAACGGTACGGTTGTCGGCACGCTGTATCGTAATGGAAAAGGGGCAATGTC
CTGGCAATATGCGCAGACATGGCTCGACACGCCGGGCGCGCGCGTGATTTCACAGTCGCTACCGTTAACGCCGCGTCGTC
AGGAAGGCGAGGTGGTGTATAACTTCTTTAGTAATTTGCTGCCTGACTCGCAGGCGATTATCTCGCGTATGCAAACGCGC
TTTAAAATCCCCACGGATCATCCCTTCGATTTGCTGGCAAGCGTTGGCCGCGACTGTGTTGGGGCAATCCAGCTCTACCC
GGAAAACAGTGAAATACCCCCTGTGACGCACATGCAGGCCACGCCGCTTTCCGATAACGAGATTGCGGCACTGCTGGAAG
GGTATCGTAATGCGCCATTGGGGATGAATGACGACCAGGATTTCAGGATTTCCATTGCAGGTGCGCAGGAAAAAACGGCA
CTGCTCTGGCATCAGAACCGCTGGCAACGCCCCAACGGCAGCACGCCCACCAGCCATATTTTCAAACTGCCCATCGGTAA
AATTGAGCAGAACAATATCGATCTGAGTGAAAGCTGCGAGAACGAATGGCTGTGTCTGCGCCTTGCCCGTGAATTCGGTT
TTTCGGTCGCCGAGGCAACGTTAGCAACCTATGCCGACAAAAAAGTGCTGATTGTTGAGCGTTTTGATCGTAAATGGTCA
CGAGACGGAAAGTGGCTGATGCGACTCCCGCAAGAAGATATGTGTCAGGCTCTCGGGTATTCACCGGCGCTGAAATATGA
ATCTCACGGCGGCCCCGGCATCGCCGAAATCATGACCTTGCTGTTGGGATCGCGCCGCTCAAACCAGGATCGCGAAACGT
TTTTCCGCACTCAGATATTTTACTGGCTGACAGGCGCGATCGATGGCCACGCAAAAAATTACAGTGTGTTTATCGAACCC
GATTCGGCGTACGTTATGACGCCGCTATACGATATTTTGTCAGCCTATCCGGTCTTCGGGCCAAAAGGAATTTCCGCACA
AAAAGCGAAAATGGCCATGGCGTTGCAGGGCAAAAACCGGCAATACCACTGGGCTCAGATTCAACCACGCCATTTCCCGG
CTACGGCTGAACGCGTTGGTTTTTCAGCTATACGCGCAAAAAAGATGATGATCGAAATGGGAAATGCGACAAATGAGATT
ATCGAGCGGGTACGTCAGTCGTTACCGATTGATTTCCCGACACATATCAGCGAAGCGATTTTTAACGGGATGGCGAAGCA
AGCTGAAAGGCTAATACGTTTAGAATAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9323.55 Da Isoelectric Point: 5.0790
>AT81502 WP_012017425.1 NZ_CP023529:c1180807-1180556 [Lelliottia amnigena]
MKITTSTMLANAMRDQRKALELTQAEAAERVGMKQTTVSGFEQNPDTSKLETLFRLLSALDLELHVVPRGQASEKDSGWT
QEW
MKITTSTMLANAMRDQRKALELTQAEAAERVGMKQTTVSGFEQNPDTSKLETLFRLLSALDLELHVVPRGQASEKDSGWT
QEW
Download Length: 252 bp
>AT81502 NZ_CP023529:c1180807-1180556 [Lelliottia amnigena]
ATGAAAATTACCACATCAACCATGCTGGCCAATGCCATGCGAGATCAGCGCAAAGCGCTGGAACTGACTCAAGCAGAAGC
CGCCGAACGCGTGGGGATGAAGCAAACCACGGTATCAGGCTTTGAACAAAATCCGGATACCAGCAAGCTGGAAACGCTAT
TTCGTCTGCTTTCAGCACTGGATTTAGAACTGCACGTTGTGCCCCGGGGCCAGGCGTCAGAAAAGGACAGCGGCTGGACG
CAGGAGTGGTAA
ATGAAAATTACCACATCAACCATGCTGGCCAATGCCATGCGAGATCAGCGCAAAGCGCTGGAACTGACTCAAGCAGAAGC
CGCCGAACGCGTGGGGATGAAGCAAACCACGGTATCAGGCTTTGAACAAAATCCGGATACCAGCAAGCTGGAAACGCTAT
TTCGTCTGCTTTCAGCACTGGATTTAGAACTGCACGTTGTGCCCCGGGGCCAGGCGTCAGAAAAGGACAGCGGCTGGACG
CAGGAGTGGTAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S5XQH7 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3S5XQW5 |