Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2497786..2497926 Replicon chromosome
Accession NZ_CP023527
Organism Citrobacter koseri strain FDAARGOS_393

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2497788..2497891 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2497786..2497926 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO700_RS12155 2493672..2494781 + 1110 WP_060816006.1 recombinase RecT -
CO700_RS12160 2494816..2495160 + 345 WP_060816005.1 hypothetical protein -
CO700_RS12165 2495153..2495761 + 609 WP_060816004.1 hypothetical protein -
CO700_RS12170 2495751..2496023 + 273 WP_060816003.1 hypothetical protein -
CO700_RS12175 2496031..2496270 + 240 WP_060816002.1 DUF4060 family protein -
CO700_RS12180 2496332..2496604 + 273 WP_060816001.1 excisionase -
CO700_RS12185 2496579..2497658 + 1080 WP_060816000.1 phage integrase Arm DNA-binding domain-containing protein -
- 2497786..2497926 + 141 - - Antitoxin
- 2497788..2497891 - 104 - - Toxin
CO700_RS12195 2498047..2498385 - 339 WP_012132024.1 YebY family protein -
CO700_RS12200 2498402..2499277 - 876 WP_077956859.1 copper homeostasis membrane protein CopD -
CO700_RS12205 2499277..2499651 - 375 WP_012132022.1 CopC domain-containing protein YobA -
CO700_RS12210 2499792..2500022 + 231 WP_024130259.1 DNA polymerase III subunit theta -
CO700_RS12215 2500128..2500784 + 657 WP_024130258.1 carbon-nitrogen hydrolase family protein -
CO700_RS12220 2500808..2501470 + 663 WP_012132019.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2442585..2503527 60942


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T81490 NZ_CP023527:c2497891-2497788 [Citrobacter koseri]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT81490 NZ_CP023527:2497786-2497926 [Citrobacter koseri]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References