Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 34810..35354 Replicon chromosome
Accession NZ_CP023525
Organism Cedecea neteri strain FDAARGOS_392

Toxin (Protein)


Gene name relE Uniprot ID A0A291DS22
Locus tag CO704_RS00175 Protein ID WP_061273470.1
Coordinates 34810..35106 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A291DS12
Locus tag CO704_RS00180 Protein ID WP_061273472.1
Coordinates 35103..35354 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO704_RS00160 29837..30739 - 903 WP_038477700.1 formate dehydrogenase subunit beta -
CO704_RS00165 30752..33802 - 3051 WP_096753937.1 formate dehydrogenase-N subunit alpha -
CO704_RS00170 33982..34806 + 825 WP_072279092.1 formate dehydrogenase accessory sulfurtransferase FdhD -
CO704_RS00175 34810..35106 - 297 WP_061273470.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CO704_RS00180 35103..35354 - 252 WP_061273472.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CO704_RS00190 36257..37795 - 1539 WP_061278600.1 aldehyde dehydrogenase -
CO704_RS00195 37932..39770 - 1839 WP_061278598.1 selenocysteine-specific translation elongation factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11557.72 Da        Isoelectric Point: 10.5084

>T81463 WP_061273470.1 NZ_CP023525:c35106-34810 [Cedecea neteri]
MSYKVKFREDALKEWHKLDKSIQQQFAKKLKKCCEEPHIPSTKLRGMKDCYKIKLRSSGFRLVYQVIDEVLVIAVVAVGK
RERSQVYNLASERMKPVR

Download         Length: 297 bp

>T81463 NZ_CP023525:c35106-34810 [Cedecea neteri]
ATGAGCTATAAGGTGAAGTTCAGGGAAGATGCGCTGAAAGAATGGCACAAGCTCGATAAATCCATTCAACAGCAGTTCGC
CAAAAAGCTTAAGAAATGCTGCGAGGAACCTCACATTCCATCAACGAAACTGCGTGGCATGAAGGATTGCTACAAAATCA
AACTACGCTCCAGCGGATTCCGGCTGGTGTACCAAGTGATAGATGAGGTGTTAGTGATCGCCGTCGTTGCCGTGGGAAAA
CGCGAGAGAAGCCAGGTTTATAACCTGGCCAGTGAACGGATGAAGCCCGTCCGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9144.47 Da        Isoelectric Point: 4.0233

>AT81463 WP_061273472.1 NZ_CP023525:c35354-35103 [Cedecea neteri]
MPSIILSDTSASVSELKKNPMATVNAGDGFPVAILNRNQPAFYCVPAALYEKMLDALDDQELVKLVNERSNQPLIEMDLD
SYL

Download         Length: 252 bp

>AT81463 NZ_CP023525:c35354-35103 [Cedecea neteri]
ATGCCTAGCATCATTCTGAGCGACACTAGCGCCAGCGTTAGCGAACTGAAAAAAAATCCTATGGCGACGGTTAATGCCGG
AGACGGCTTCCCGGTTGCAATACTGAACCGCAACCAGCCGGCGTTTTACTGCGTACCAGCCGCGCTGTATGAAAAAATGC
TTGATGCGCTGGATGACCAGGAGTTGGTAAAGCTGGTCAATGAACGCAGCAACCAGCCACTGATTGAGATGGATTTGGAC
AGCTATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A291DS22

Antitoxin

Source ID Structure
AlphaFold DB A0A291DS12

References