Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 108032..109875 Replicon chromosome
Accession NZ_CP023523
Organism Burkholderia gladioli pv. gladioli strain FDAARGOS_389

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag CO712_RS19660 Protein ID WP_096752827.1
Coordinates 108032..108997 (+) Length 322 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag CO712_RS19665 Protein ID WP_044275309.1
Coordinates 109015..109875 (+) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO712_RS19630 103340..104419 - 1080 WP_017921239.1 porin -
CO712_RS37415 104529..104819 + 291 WP_145756556.1 hypothetical protein -
CO712_RS19635 104834..105151 + 318 WP_013689902.1 non-heme iron oxygenase ferredoxin subunit -
CO712_RS19640 105154..105465 + 312 WP_096750799.1 hypothetical protein -
CO712_RS19645 105507..106616 + 1110 WP_096750800.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
CO712_RS19650 106609..107379 + 771 WP_036038834.1 SDR family oxidoreductase -
CO712_RS19655 107478..108005 + 528 WP_036038832.1 cupin domain-containing protein -
CO712_RS19660 108032..108997 + 966 WP_096752827.1 alpha/beta fold hydrolase Toxin
CO712_RS19665 109015..109875 + 861 WP_044275309.1 IclR family transcriptional regulator Antitoxin
CO712_RS19670 109872..110669 + 798 WP_096750801.1 SDR family oxidoreductase -
CO712_RS19675 110662..112335 + 1674 WP_096750802.1 thiamine pyrophosphate-binding protein -
CO712_RS19680 112328..113161 + 834 WP_096750803.1 aspartate dehydrogenase -
CO712_RS19685 113238..114728 + 1491 WP_046574265.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(66-304)

Antitoxin

Transcription regulator IclR, N-terminal

(25-73)


Sequences

Toxin        


Download         Length: 322 a.a.        Molecular weight: 32749.19 Da        Isoelectric Point: 7.0962

>T81457 WP_096752827.1 NZ_CP023523:108032-108997 [Burkholderia gladioli pv. gladioli]
MSEIDPRGAEAEAGPDAALAARLGQFPARRIAIREAGLIGWRESGPVQGAGDSTARAAAGERALPVVLLHGIGSGAASWL
AQLDTLGASRRVLAWDAPGYGESTPVAPASPLAADYAASLAGWLDALAIERCVLVGHSLGAIVAGAFARRHAGRLAGLLL
VSPAAGYGAAPAATRDERRDARLAMLAALGPAGLAEQRSANMLSAHAGEAARAWVRRVMAQVKPAGYTQATHLLANADLA
ADLSAWRAMTDAAGAARVEVMVGAEDGITPPNACERIAAAAGVALHVVPRAGHAGYVEAPERYSALIGAFCARCDESWRQ
A

Download         Length: 966 bp

>T81457 NZ_CP023523:108032-108997 [Burkholderia gladioli pv. gladioli]
ATGAGCGAAATCGATCCGCGCGGGGCCGAGGCAGAGGCCGGGCCCGACGCGGCCCTGGCCGCCCGGCTCGGGCAGTTTCC
GGCGCGGCGCATCGCCATTCGCGAAGCCGGGCTGATCGGCTGGCGCGAATCGGGTCCAGTGCAGGGAGCTGGCGATTCGA
CGGCACGCGCGGCGGCTGGCGAGCGGGCATTGCCGGTGGTGCTGCTGCACGGCATCGGCTCGGGCGCGGCCTCGTGGCTG
GCCCAGCTCGACACGCTCGGCGCCTCGCGTCGCGTGCTGGCCTGGGACGCGCCCGGTTATGGCGAATCGACGCCGGTCGC
GCCGGCCTCGCCGCTGGCGGCCGATTACGCGGCGTCGCTGGCCGGCTGGCTCGACGCGCTCGCCATCGAGCGCTGCGTGC
TGGTGGGACACTCGCTCGGCGCGATCGTGGCCGGCGCCTTCGCGCGCCGGCATGCCGGGCGGCTGGCCGGCTTGCTGCTG
GTTTCGCCGGCCGCCGGCTACGGCGCGGCGCCGGCTGCCACGCGCGACGAACGGCGCGACGCGCGGCTCGCGATGCTGGC
CGCGCTCGGTCCCGCGGGCCTGGCCGAACAACGCAGCGCCAACATGCTGTCGGCGCATGCCGGCGAGGCCGCGCGCGCCT
GGGTGCGCCGCGTGATGGCGCAGGTGAAGCCGGCCGGCTACACGCAGGCCACCCACCTGCTCGCGAACGCCGACCTGGCC
GCCGATCTCTCCGCCTGGCGGGCGATGACCGACGCCGCCGGTGCCGCGCGCGTGGAGGTGATGGTGGGCGCCGAGGACGG
CATCACGCCGCCGAACGCCTGCGAGCGGATCGCGGCGGCGGCCGGCGTGGCGCTGCACGTCGTGCCGCGCGCCGGCCATG
CCGGCTACGTGGAGGCACCCGAGCGCTACTCGGCGCTGATCGGCGCGTTCTGCGCGCGCTGCGACGAATCATGGAGACAG
GCATGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31049.35 Da        Isoelectric Point: 6.5132

>AT81457 WP_044275309.1 NZ_CP023523:109015-109875 [Burkholderia gladioli pv. gladioli]
MRSEPADSGAPEADAANGAYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNY
RLGVAVLRLGFEYLSSLELTDLGLPVIEGLREATGFTTHIVIRDGRDVVFVAKAQSAAPAFSSIRVNVGTRLPAHATTHG
HVLMGDLSEAELRALYPERQLERATRATPDSLEALLALVREDAARGYGISNSSFERGISVVTAPVRNDTQRIVAAVTVTV
PKPEIDAALIADGLVEKVVRAANELSRRLNYRSDDENSYLKALGLR

Download         Length: 861 bp

>AT81457 NZ_CP023523:109015-109875 [Burkholderia gladioli pv. gladioli]
CTGCGAAGCGAGCCGGCCGACAGCGGCGCGCCCGAGGCGGATGCCGCGAACGGCGCCTACGTGGTACCGGGCCTCGAACG
CGGGCTGCGGATCCTCGCGGAATTCTCGCCGCGCGAGCCGGTGCTGGGCGCGCCGGAATTGTCGAAGCGGCTCGGCATTC
CGCGCACCACGGTGTTCCGGCTGCTGCAGACGCTCGAATCGCTGGGCTTCCTGGAGCGCGCCGACAAGGACCGCAATTAC
CGGCTCGGCGTGGCGGTGCTGCGCCTGGGCTTCGAATACTTGAGCTCGCTGGAGCTGACCGACCTGGGCCTGCCGGTGAT
CGAGGGCCTGCGCGAGGCGACCGGCTTCACCACCCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCCAAGG
CGCAGAGCGCGGCGCCGGCCTTCAGCTCGATTCGCGTCAACGTCGGCACGCGGCTGCCCGCGCATGCCACCACCCACGGC
CACGTGCTGATGGGCGACCTGAGCGAGGCCGAGCTGCGCGCGCTGTACCCCGAGCGCCAGCTCGAACGCGCCACGCGCGC
CACGCCCGACAGCCTGGAGGCGCTGCTCGCGCTGGTCCGCGAGGATGCCGCGCGCGGCTACGGCATCAGCAACTCGTCGT
TCGAGCGCGGCATCTCGGTGGTCACCGCGCCGGTGCGCAACGACACGCAGCGCATCGTGGCGGCCGTCACGGTGACGGTG
CCGAAACCCGAGATCGACGCGGCGCTGATCGCCGACGGCCTGGTCGAGAAGGTCGTGAGGGCGGCCAATGAACTGTCGCG
GCGGCTCAATTACCGCTCCGATGATGAGAACTCCTATCTGAAGGCATTGGGATTGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References