Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 4072544..4073821 Replicon chromosome
Accession NZ_CP023522
Organism Burkholderia gladioli pv. gladioli strain FDAARGOS_389

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag CO712_RS18700 Protein ID WP_096750459.1
Coordinates 4073237..4073821 (+) Length 195 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CO712_RS18695 Protein ID WP_096750458.1
Coordinates 4072544..4073134 (+) Length 197 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO712_RS18675 4069157..4069585 + 429 WP_082193480.1 DUF4212 domain-containing protein -
CO712_RS18680 4069579..4071594 + 2016 WP_036049934.1 VC_2705 family sodium/solute symporter -
CO712_RS18685 4071638..4072061 + 424 Protein_3682 hypothetical protein -
CO712_RS18690 4072128..4072391 + 264 WP_096750457.1 PAAR domain-containing protein -
CO712_RS18695 4072544..4073134 + 591 WP_096750458.1 helix-turn-helix domain-containing protein Antitoxin
CO712_RS18700 4073237..4073821 + 585 WP_096750459.1 HD domain-containing protein Toxin
CO712_RS18710 4074503..4074751 + 249 WP_096750460.1 hypothetical protein -
CO712_RS18715 4074802..4075203 - 402 WP_096750461.1 hypothetical protein -
CO712_RS18720 4075219..4075437 - 219 WP_096750462.1 hypothetical protein -
CO712_RS18725 4075449..4076078 - 630 WP_096750463.1 hypothetical protein -
CO712_RS18730 4076075..4076632 - 558 WP_096750464.1 hypothetical protein -
CO712_RS18735 4076629..4076853 - 225 WP_096750465.1 hypothetical protein -
CO712_RS18740 4076850..4077326 - 477 WP_096750466.1 hypothetical protein -
CO712_RS18745 4077323..4077670 - 348 WP_096750467.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4069579..4115373 45794


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(16-171)

Antitoxin

Cro/C1-type helix-turn-helix domain

(24-74)


Sequences

Toxin        


Download         Length: 195 a.a.        Molecular weight: 21519.26 Da        Isoelectric Point: 4.8864

>T81456 WP_096750459.1 NZ_CP023522:4073237-4073821 [Burkholderia gladioli pv. gladioli]
MDDALIDARLNFLRGCERLKDVLRSGHTSGGRCESTAEHSWRLALMAMVLMDQLGEVDRGRVLELCLVHDLGEALGDDVP
APEQAPGSDKDAVERRDLLRLGETLDAPMRERIVALWDEYARAATPEARAVKALDKIETILQHTQGENPPDFDYAFNLAY
GQAHTRKVPALQRFRERVDEATRERMAGAGGPSG

Download         Length: 585 bp

>T81456 NZ_CP023522:4073237-4073821 [Burkholderia gladioli pv. gladioli]
ATGGACGATGCGTTGATCGACGCACGACTGAATTTCCTGCGCGGCTGCGAGCGCCTGAAGGATGTGCTGCGCAGCGGCCA
TACCTCGGGTGGCCGATGCGAGAGCACGGCCGAGCACAGTTGGCGGCTCGCGTTGATGGCGATGGTGCTGATGGATCAAT
TGGGCGAGGTCGACCGCGGCAGGGTGCTCGAGCTCTGCCTGGTGCACGACCTGGGCGAGGCGCTGGGCGACGACGTGCCG
GCGCCCGAGCAGGCCCCGGGCAGCGACAAGGATGCCGTCGAGCGACGCGATCTGCTGCGCCTCGGCGAAACGCTCGATGC
GCCGATGCGCGAGAGGATCGTCGCGTTGTGGGACGAGTATGCGCGGGCGGCCACGCCGGAAGCGCGCGCGGTGAAGGCGC
TCGACAAGATCGAGACGATCCTGCAGCACACGCAGGGCGAGAATCCGCCCGATTTCGACTATGCGTTCAACCTCGCGTAT
GGGCAGGCGCATACCCGCAAGGTGCCGGCGCTGCAGCGGTTTCGCGAGCGTGTCGACGAGGCGACGCGCGAGCGGATGGC
CGGTGCCGGCGGGCCTTCGGGCTGA

Antitoxin


Download         Length: 197 a.a.        Molecular weight: 21561.41 Da        Isoelectric Point: 8.3928

>AT81456 WP_096750458.1 NZ_CP023522:4072544-4073134 [Burkholderia gladioli pv. gladioli]
MKPISSNQATTTSLPPSELACSPGASLRRWRTLRRIKQEHAAALFGVSQSTISRWEAGTQAVSHEELRRIEACLSARLDS
AADRALERLVSHHTRPVHLVCDLTHRLLACSTPRAAEFAAPLSSLMGASLWPFATAEIVAREQSLRDAGWQDHPAPSIEF
DTGSNDSPQVPIRASRCRWTRFTLSDGTLARLVETL

Download         Length: 591 bp

>AT81456 NZ_CP023522:4072544-4073134 [Burkholderia gladioli pv. gladioli]
ATGAAACCGATATCGTCTAACCAGGCAACGACCACGTCCTTGCCGCCGTCCGAGCTGGCCTGTTCGCCGGGCGCGAGCCT
GCGTCGGTGGCGCACGCTGCGCCGGATCAAGCAGGAGCATGCGGCGGCGCTGTTCGGCGTATCGCAGTCGACGATATCGC
GCTGGGAAGCCGGCACCCAGGCGGTGTCGCACGAGGAACTGCGGCGCATCGAGGCCTGCTTGTCGGCGCGCCTCGACTCG
GCGGCGGATCGCGCGCTCGAGCGCCTCGTGAGCCATCACACCCGTCCCGTTCATCTCGTGTGCGACCTCACGCACCGGCT
GCTGGCCTGCTCCACGCCGCGAGCCGCGGAGTTCGCGGCGCCGCTGTCGTCGCTGATGGGCGCGTCGCTCTGGCCGTTCG
CGACGGCCGAGATCGTGGCGCGCGAGCAGTCCTTGCGCGATGCGGGCTGGCAAGATCATCCGGCACCCTCGATCGAATTC
GATACCGGGTCCAACGACTCGCCGCAGGTGCCGATTCGTGCGAGCCGCTGCCGCTGGACGCGTTTCACCTTGTCCGACGG
GACGCTGGCGCGCCTGGTCGAAACGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References