Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4010638..4011416 Replicon chromosome
Accession NZ_CP023504
Organism Citrobacter werkmanii strain FDAARGOS_364

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CO701_RS19910 Protein ID WP_096758632.1
Coordinates 4010638..4011126 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CO701_RS19915 Protein ID WP_096758633.1
Coordinates 4011123..4011416 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO701_RS19885 4005804..4006712 + 909 WP_096758628.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO701_RS19895 4007295..4007612 - 318 WP_096758630.1 hypothetical protein -
CO701_RS19900 4007743..4009206 + 1464 WP_096758631.1 hypothetical protein -
CO701_RS19905 4010174..4010353 + 180 Protein_3772 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
CO701_RS19910 4010638..4011126 - 489 WP_096758632.1 GNAT family N-acetyltransferase Toxin
CO701_RS19915 4011123..4011416 - 294 WP_096758633.1 DUF1778 domain-containing protein Antitoxin
CO701_RS19920 4012084..4015338 - 3255 WP_096758634.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17605.61 Da        Isoelectric Point: 7.7294

>T81428 WP_096758632.1 NZ_CP023504:c4011126-4010638 [Citrobacter werkmanii]
MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQLSGASRTFVCCDDVKVMAYYSLASSAVTTNTAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGLGRALMRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLVG
SV

Download         Length: 489 bp

>T81428 NZ_CP023504:c4011126-4010638 [Citrobacter werkmanii]
ATGATCTCCGCCCCTGAGCCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGCGTGGATTCTATGGATAACTG
GCTGAAACAACGGGCGATGAAGAACCAGCTTTCCGGCGCATCCCGCACGTTTGTCTGCTGCGATGATGTTAAGGTGATGG
CTTACTACTCGCTGGCATCCAGCGCCGTAACGACAAATACGGCACCCGGTCGTTTTCGCCGTAATATGCCTGACCCAATC
CCGGTGGTGGTGCTGGGGCGTCTGGCGGTGGATAAGTCGTTGCACGGGCAGGGCTTAGGGCGGGCGTTGATGAGGGATGC
CGGGCTACGGGTAATTCAGGTGGCGGAGACTATCGGCATTCGCGGAATGCTGGTTCATGCCTTGTCGGATGAAGCGCGGG
AGTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCAATGGACCCGATGATGCTGATGGTGACGCTGGGGGATTTGGTGGGA
AGTGTTTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10932.58 Da        Isoelectric Point: 9.8590

>AT81428 WP_096758633.1 NZ_CP023504:c4011416-4011123 [Citrobacter werkmanii]
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYQEFLTRLDQAPAPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp

>AT81428 NZ_CP023504:c4011416-4011123 [Citrobacter werkmanii]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAACCTGCGCATCAAGCCCGCTGAGCGCGATCTTATCGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGTTGGAAGCTGCCCGCGCCGCCGCAGAGGAAGCGCTGA
TCGAACAACGTATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTGACTCGTCTGGATCAGGCTCCTGCGCCTAAT
GCCGCACTGCGTAAAACAATGCAGACTCCTGCGCCGTGGGAACAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References