Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2532475..2532620 Replicon chromosome
Accession NZ_CP023487
Organism Klebsiella pneumoniae subsp. pneumoniae strain ST101:960186733

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2532511..2532613 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2532475..2532620 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AN663_RS12805 2527605..2529665 + 2061 WP_004151449.1 oligopeptidase B -
AN663_RS12810 2529669..2530328 - 660 WP_002911407.1 exodeoxyribonuclease X -
AN663_RS12815 2530407..2530637 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AN663_RS12820 2530750..2531124 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AN663_RS12825 2531128..2531997 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
AN663_RS12830 2532014..2532352 + 339 WP_002911404.1 YebY family protein -
- 2532475..2532620 - 146 - - Antitoxin
- 2532511..2532613 + 103 - - Toxin
AN663_RS30085 2532988..2533131 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AN663_RS12840 2533236..2534204 - 969 WP_004151446.1 VirK/YbjX family protein -
AN663_RS12845 2534361..2535014 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
AN663_RS12850 2535011..2535202 - 192 WP_002911395.1 YebW family protein -
AN663_RS12855 2535300..2535539 - 240 WP_002911393.1 YebV family protein -
AN663_RS12860 2535655..2537088 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T81372 NZ_CP023487:2532511-2532613 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT81372 NZ_CP023487:c2532620-2532475 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References