Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafN(antitoxin) |
| Location | 1974382..1974947 | Replicon | chromosome |
| Accession | NZ_CP023485 | ||
| Organism | Vibrio parahaemolyticus strain FORC_071 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | FORC71_RS10015 | Protein ID | WP_065780667.1 |
| Coordinates | 1974382..1974669 (-) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3BLE1 |
| Locus tag | FORC71_RS10020 | Protein ID | WP_000086647.1 |
| Coordinates | 1974666..1974947 (-) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FORC71_RS09955 | 1969470..1970156 | - | 687 | WP_065780677.1 | hypothetical protein | - |
| FORC71_RS09960 | 1970180..1970323 | - | 144 | WP_080540085.1 | DUF3265 domain-containing protein | - |
| FORC71_RS09965 | 1970286..1970762 | - | 477 | WP_021704949.1 | GNAT family N-acetyltransferase | - |
| FORC71_RS09970 | 1970796..1970913 | - | 118 | Protein_1814 | DUF3265 domain-containing protein | - |
| FORC71_RS09975 | 1970904..1971356 | - | 453 | WP_120416733.1 | hypothetical protein | - |
| FORC71_RS09980 | 1971565..1971813 | + | 249 | WP_005377003.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| FORC71_RS09985 | 1971803..1972093 | + | 291 | WP_025536831.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| FORC71_RS09990 | 1972071..1972223 | - | 153 | WP_120416734.1 | DUF3265 domain-containing protein | - |
| FORC71_RS09995 | 1972220..1972558 | - | 339 | WP_086459346.1 | hypothetical protein | - |
| FORC71_RS10000 | 1972706..1973260 | - | 555 | WP_069547737.1 | hypothetical protein | - |
| FORC71_RS10005 | 1973774..1973902 | - | 129 | WP_120416856.1 | DUF3265 domain-containing protein | - |
| FORC71_RS10015 | 1974382..1974669 | - | 288 | WP_065780667.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| FORC71_RS10020 | 1974666..1974947 | - | 282 | WP_000086647.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| FORC71_RS10025 | 1975113..1975547 | - | 435 | WP_029811088.1 | hypothetical protein | - |
| FORC71_RS10030 | 1975757..1976149 | - | 393 | WP_025502499.1 | nuclear transport factor 2 family protein | - |
| FORC71_RS10035 | 1976178..1976309 | - | 132 | WP_086585508.1 | DUF3265 domain-containing protein | - |
| FORC71_RS10045 | 1976797..1976889 | - | 93 | WP_077200619.1 | DUF3265 domain-containing protein | - |
| FORC71_RS10050 | 1976916..1977500 | - | 585 | WP_120416735.1 | hypothetical protein | - |
| FORC71_RS25790 | 1977530..1977643 | - | 114 | WP_193251011.1 | DUF3265 domain-containing protein | - |
| FORC71_RS10070 | 1978188..1979228 | - | 1041 | WP_120416736.1 | DUF4062 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1856333..1989263 | 132930 | |
| - | inside | Integron | - | - | 1927077..1988138 | 61061 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10976.66 Da Isoelectric Point: 5.1021
>T81365 WP_065780667.1 NZ_CP023485:c1974669-1974382 [Vibrio parahaemolyticus]
MKVVWSPLALQKLGDAAEFISLDNPPAAEKWVNEVFDKAELLGSMPEMGRFVPEMPNTNYREIIFGHYRIIYSLNHEIRV
LTVRNCRQILSENDV
MKVVWSPLALQKLGDAAEFISLDNPPAAEKWVNEVFDKAELLGSMPEMGRFVPEMPNTNYREIIFGHYRIIYSLNHEIRV
LTVRNCRQILSENDV
Download Length: 288 bp
>T81365 NZ_CP023485:c1974669-1974382 [Vibrio parahaemolyticus]
ATGAAAGTAGTTTGGTCTCCATTAGCGCTTCAGAAGTTAGGCGATGCAGCGGAATTTATTTCTTTGGATAATCCACCTGC
GGCAGAAAAGTGGGTAAACGAAGTTTTTGATAAAGCTGAACTACTTGGAAGTATGCCTGAAATGGGGCGCTTTGTTCCTG
AAATGCCCAATACTAACTATCGTGAGATCATTTTTGGTCACTATCGTATCATCTATAGCTTAAATCATGAGATCCGCGTA
CTAACAGTTCGTAATTGTCGTCAAATATTGTCAGAAAATGACGTGTAA
ATGAAAGTAGTTTGGTCTCCATTAGCGCTTCAGAAGTTAGGCGATGCAGCGGAATTTATTTCTTTGGATAATCCACCTGC
GGCAGAAAAGTGGGTAAACGAAGTTTTTGATAAAGCTGAACTACTTGGAAGTATGCCTGAAATGGGGCGCTTTGTTCCTG
AAATGCCCAATACTAACTATCGTGAGATCATTTTTGGTCACTATCGTATCATCTATAGCTTAAATCATGAGATCCGCGTA
CTAACAGTTCGTAATTGTCGTCAAATATTGTCAGAAAATGACGTGTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10398.91 Da Isoelectric Point: 5.8650
>AT81365 WP_000086647.1 NZ_CP023485:c1974947-1974666 [Vibrio parahaemolyticus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
Download Length: 282 bp
>AT81365 NZ_CP023485:c1974947-1974666 [Vibrio parahaemolyticus]
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCTTTGTCTGAGTTTCGTGCCGGTGTAGCTTCATACATCAAACAAAT
CAATGAGACTCGTCGTCCATTGGTTATTACTCAACGTGGCAAAGGTGTTGCTGTTGTTCTCGATGTTGCTGAGTATGAAG
CAATGCAAGAGAAGATCGAGTTACTGGAAGAAATGCGCACAGCTGAAGCTCAATTAGCTTCAGGCCTTGGTGTTTCAAAT
GATGATGCTCGTGCTCAAGTACTGGGGCGCATTAAGAAATGA
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCTTTGTCTGAGTTTCGTGCCGGTGTAGCTTCATACATCAAACAAAT
CAATGAGACTCGTCGTCCATTGGTTATTACTCAACGTGGCAAAGGTGTTGCTGTTGTTCTCGATGTTGCTGAGTATGAAG
CAATGCAAGAGAAGATCGAGTTACTGGAAGAAATGCGCACAGCTGAAGCTCAATTAGCTTCAGGCCTTGGTGTTTCAAAT
GATGATGCTCGTGCTCAAGTACTGGGGCGCATTAAGAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|