Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yeeU/CbtA-CbeA
Location 3930738..3931485 Replicon chromosome
Accession NZ_CP023484
Organism Dickeya sp. Secpp 1600

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag CPA59_RS17525 Protein ID WP_102802208.1
Coordinates 3930738..3931058 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag CPA59_RS17530 Protein ID WP_102802209.1
Coordinates 3931084..3931485 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPA59_RS17505 3926578..3927897 + 1320 WP_102802204.1 site-specific integrase -
CPA59_RS17510 3927972..3929021 - 1050 WP_102802205.1 macro domain-containing protein -
CPA59_RS17515 3929035..3929682 - 648 WP_102802206.1 DUF4433 domain-containing protein -
CPA59_RS17520 3929787..3930620 - 834 WP_102802207.1 DUF4942 domain-containing protein -
CPA59_RS17525 3930738..3931058 - 321 WP_102802208.1 TA system toxin CbtA family protein Toxin
CPA59_RS17530 3931084..3931485 - 402 WP_102802209.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
CPA59_RS17535 3931485..3931958 - 474 WP_012768688.1 DNA repair protein RadC -
CPA59_RS17540 3931989..3932810 - 822 WP_102802210.1 DUF945 domain-containing protein -
CPA59_RS17545 3932907..3933773 - 867 WP_102802211.1 GTPase family protein -
CPA59_RS17550 3934510..3935001 + 492 WP_102802739.1 hypothetical protein -
CPA59_RS17555 3935005..3936171 + 1167 WP_102802212.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(6-105)

Antitoxin

Antitoxin CbeA

(22-121)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11955.60 Da        Isoelectric Point: 5.0757

>T81361 WP_102802208.1 NZ_CP023484:c3931058-3930738 [Dickeya sp. Secpp 1600]
MQTPSPSPAREASSCLSPVNVWQQLLTYLLDKHYGLTLNDTPFCEEAEIQAHLDAGVSLPDAVNFLVERYELVRIDRSGF
SWQEQKPFLNAVDILRARRATGLLKP

Download         Length: 321 bp

>T81361 NZ_CP023484:c3931058-3930738 [Dickeya sp. Secpp 1600]
ATGCAAACACCATCCCCCTCCCCGGCGCGGGAGGCATCGTCATGCCTGTCACCTGTAAATGTCTGGCAACAGTTATTAAC
TTACCTGCTGGACAAGCACTACGGGCTGACGCTCAACGACACGCCGTTTTGTGAAGAAGCTGAGATCCAGGCCCACCTCG
ACGCCGGAGTTTCGCTGCCGGACGCCGTGAACTTTCTGGTGGAGCGCTATGAGCTGGTGCGCATCGACCGCAGCGGTTTT
AGCTGGCAGGAGCAAAAACCGTTTCTGAACGCGGTCGATATTCTCCGCGCCAGACGCGCCACCGGCCTGCTCAAACCATA
A

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14770.91 Da        Isoelectric Point: 6.9476

>AT81361 WP_102802209.1 NZ_CP023484:c3931485-3931084 [Dickeya sp. Secpp 1600]
MPFTVIPSTCQEKRTLSLSDAPEWGLEHTLRPRFGARLVQEGCRLHFLADRAGVTGTFSATVACHLEHRFPLLVRQLEQK
LVTGELDPYRQQRVTLHDGVLTCEADTLGSAGYVYITIYPTTAATPTTTFPLP

Download         Length: 402 bp

>AT81361 NZ_CP023484:c3931485-3931084 [Dickeya sp. Secpp 1600]
ATGCCTTTTACCGTCATTCCATCAACCTGTCAGGAGAAAAGAACCTTGTCATTATCGGATGCCCCGGAATGGGGACTTGA
ACACACCCTGAGACCGCGCTTTGGAGCCCGGCTGGTACAGGAGGGGTGTCGCCTGCATTTTCTCGCCGACCGTGCCGGTG
TGACCGGCACTTTCAGTGCAACCGTGGCCTGCCATCTGGAACACCGTTTCCCACTGCTGGTGAGACAACTGGAGCAAAAG
CTTGTGACCGGTGAGCTCGATCCCTACCGACAGCAACGCGTCACGCTGCATGACGGCGTACTGACCTGCGAGGCCGATAC
ACTGGGTAGTGCTGGCTACGTCTATATCACGATTTACCCGACCACGGCGGCCACACCGACAACCACATTCCCTTTACCTT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References