Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1692810..1693363 Replicon chromosome
Accession NZ_CP023484
Organism Dickeya sp. Secpp 1600

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag CPA59_RS07595 Protein ID WP_027712562.1
Coordinates 1693049..1693363 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag CPA59_RS07590 Protein ID WP_107758993.1
Coordinates 1692810..1693046 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPA59_RS07580 1689353..1690696 - 1344 WP_107758991.1 DNA (cytosine-5-)-methyltransferase -
CPA59_RS22850 1690698..1691120 - 423 WP_159077929.1 hypothetical protein -
CPA59_RS07585 1691549..1692490 + 942 WP_107758992.1 DUF1738 domain-containing protein -
CPA59_RS07590 1692810..1693046 + 237 WP_107758993.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
CPA59_RS07595 1693049..1693363 + 315 WP_027712562.1 CcdB family protein Toxin
CPA59_RS07600 1693360..1693614 - 255 WP_107758994.1 mobilization protein mobC -
CPA59_RS07605 1693791..1694342 - 552 WP_107758995.1 hypothetical protein -
CPA59_RS07610 1694607..1694723 + 117 Protein_1462 transposase -
CPA59_RS07615 1694942..1695964 - 1023 WP_100848778.1 IS110 family transposase -
CPA59_RS07620 1696031..1697025 + 995 Protein_1464 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11472.38 Da        Isoelectric Point: 7.9859

>T81350 WP_027712562.1 NZ_CP023484:1693049-1693363 [Dickeya sp. Secpp 1600]
MQFTVYGNTGKSAVYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRNQVKAAIDFLIDGI

Download         Length: 315 bp

>T81350 NZ_CP023484:1693049-1693363 [Dickeya sp. Secpp 1600]
ATGCAATTCACCGTATACGGTAATACCGGGAAAAGCGCCGTTTATCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
GCAGTTAAATCGTCGGATAGTGATCCCGTTGCTCCCTGTTGAAAAGTATCCGGCAGGCCGCCGACCGGATCGCCTGGTCC
CCGTCGTCAGGCTGACGGACGGTAAAGAATACGCCGTAATGACGCACGAGCTGGCAAGTATCCCTGTGCAGGCTCTGGGG
GCGGTGTTTTGTGATGCGTCGCAGTACCGTAATCAGGTAAAGGCCGCAATAGATTTCCTCATTGACGGCATTTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9031.05 Da        Isoelectric Point: 6.4792

>AT81350 WP_107758993.1 NZ_CP023484:1692810-1693046 [Dickeya sp. Secpp 1600]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLTAALDTELRHHEAKKWQEENREAIDALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp

>AT81350 NZ_CP023484:1692810-1693046 [Dickeya sp. Secpp 1600]
ATGACCGCGAAACAACGCAACACGCAGAGCGTGACCATGACGGTAGAGCGTGCCTTACTGGTCCGGGCGCGTGAAGCGGG
CATTAACTTGAGTGCCACCCTGACAGCTGCCCTGGATACAGAGCTTCGCCACCATGAAGCGAAAAAATGGCAGGAAGAGA
ACAGGGAAGCCATCGACGCATTAAACCGTTTTCATGATGAACACGGCTGTTTCAGCGATGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References