Detailed information of TA system TA081348

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 1018149..1018675
• Replicon: chromosome
• Accession: NZ_CP023484
• Organism: Dickeya sp. Secpp 1600

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: CPA59_RS04645
• Protein ID: WP_107758790.1
• Coordinates: 1018149..1018454 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: CPA59_RS04650
• Protein ID: WP_038918044.1
• Coordinates: 1018457..1018675 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPA59_RS04635	1013369..1016002	-	2634	WP_107758789.1	DEAD/DEAH box helicase family protein	-
CPA59_RS04640	1015993..1017719	-	1727	Protein_889	site-specific DNA-methyltransferase	-
CPA59_RS04645	1018149..1018454	-	306	WP_107758790.1	type II toxin-antitoxin system toxin CcdB	Toxin
CPA59_RS04650	1018457..1018675	-	219	WP_038918044.1	type II toxin-antitoxin system antitoxin CcdA	Antitoxin
CPA59_RS04655	1018734..1019477	-	744	WP_107758791.1	molybdopterin-guanine dinucleotide biosynthesis protein MobC	-
CPA59_RS04665	1020380..1020721	-	342	WP_107758793.1	hypothetical protein	-
CPA59_RS22970	1020862..1021032	+	171	WP_162847981.1	hypothetical protein	-
CPA59_RS04670	1021174..1022421	-	1248	WP_107758794.1	tyrosine-type recombinase/integrase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1006319..1022602	16283

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin CcdB (2-100)

Antitoxin

• Post-segregation antitoxin CcdA (2-72)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11710.60 Da
• Isoelectric Point: 4.8307

>T81348 WP_107758790.1 NZ_CP023484:c1018454-1018149 [Dickeya sp. Secpp 1600]
MQFIVYQYKRSSHYKMFVDVQSDIVETPKRRMVIPLIESHQLSEKVNKTLFPLIRIDGEDYRLMTTELSSVPVEVIGEVI
ADLGGYADEIKDAINLMFWGI

Nucleotide

• Length: 306 bp

>T81348 NZ_CP023484:c1018454-1018149 [Dickeya sp. Secpp 1600]
ATGCAATTCATTGTTTATCAATATAAAAGATCCAGCCACTACAAAATGTTTGTCGATGTGCAAAGCGATATTGTTGAAAC
ACCAAAACGGCGCATGGTCATCCCGCTTATCGAATCGCATCAGCTGTCTGAGAAAGTGAATAAAACGCTGTTCCCGCTGA
TCCGCATCGATGGGGAAGATTATCGGCTGATGACCACTGAGCTATCTAGCGTTCCCGTCGAAGTCATTGGTGAAGTGATT
GCGGATCTTGGCGGCTACGCAGATGAGATCAAGGATGCTATTAATCTTATGTTTTGGGGGATATGA

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 8220.17 Da
• Isoelectric Point: 7.0142

>AT81348 WP_038918044.1 NZ_CP023484:c1018675-1018457 [Dickeya sp. Secpp 1600]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNEAIGKEARRIRAEEWKKENREGMEEVARFIAQNGSFADENRNW

Nucleotide

• Length: 219 bp

>AT81348 NZ_CP023484:c1018675-1018457 [Dickeya sp. Secpp 1600]
ATGAAACACCGCGTCAGCGTTACCGTGGACAAAGACAATTATCAGGTTCTGAGTGCCGCCGGGGTCAATATTTCCGGGCT
GGTGAATGAGGCCATTGGCAAAGAAGCCCGCCGCATCAGGGCTGAAGAGTGGAAGAAGGAGAATCGCGAAGGGATGGAAG
AAGTCGCCCGATTTATCGCACAGAATGGCTCCTTTGCGGATGAAAACAGGAACTGGTGA