Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 720786..721464 | Replicon | chromosome |
Accession | NZ_CP023484 | ||
Organism | Dickeya sp. Secpp 1600 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A2K8QJH4 |
Locus tag | CPA59_RS03400 | Protein ID | WP_049854564.1 |
Coordinates | 721033..721464 (+) | Length | 144 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A2K8QSU7 |
Locus tag | CPA59_RS03395 | Protein ID | WP_023637600.1 |
Coordinates | 720786..721052 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CPA59_RS03375 | 717232..717882 | + | 651 | WP_049854566.1 | LysE family translocator | - |
CPA59_RS03380 | 717953..718561 | - | 609 | WP_038917841.1 | HD domain-containing protein | - |
CPA59_RS03385 | 718772..719422 | + | 651 | WP_038917842.1 | hemolysin III family protein | - |
CPA59_RS03390 | 719495..720475 | - | 981 | WP_107758697.1 | tRNA-modifying protein YgfZ | - |
CPA59_RS03395 | 720786..721052 | + | 267 | WP_023637600.1 | FAD assembly factor SdhE | Antitoxin |
CPA59_RS03400 | 721033..721464 | + | 432 | WP_049854564.1 | protein YgfX | Toxin |
CPA59_RS03405 | 721563..722081 | - | 519 | WP_107758698.1 | flavodoxin FldB | - |
CPA59_RS03410 | 722210..723535 | - | 1326 | WP_107758699.1 | MHS family MFS transporter | - |
CPA59_RS03415 | 723798..724697 | + | 900 | WP_038917846.1 | site-specific tyrosine recombinase XerD | - |
CPA59_RS03420 | 724786..725502 | + | 717 | WP_049854562.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 144 a.a. Molecular weight: 16793.54 Da Isoelectric Point: 11.7737
>T81347 WP_049854564.1 NZ_CP023484:721033-721464 [Dickeya sp. Secpp 1600]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLLQHPLQGTESSRHH
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLLQHPLQGTESSRHH
Download Length: 432 bp
>T81347 NZ_CP023484:721033-721464 [Dickeya sp. Secpp 1600]
GTGGCCCAGTGGCAATGTGATTTGCGTGTATCCTGGCGCATGCAGTTGTTTTCTCTGCTGACGCACGGGTTCCTGGTGCT
GATGATCCTGCTGGCTCCCTGGCCGGACGGCTATGCGCCGCTGTGGCTGGGGTTGGTGACGCTGGTGGTGTTCGGTTTCG
TGCGCAGTCAGCGCATCATCAAGTCGCGTCAGGGGGAAATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAGCAGCGT
GACTGGCAGATAGCCCGGCGACCGTGGGTGATGCGCAACGGCGTGTTGCTGTCGTTGCGGGCGACGACCGGTAAAGGGCA
TCAGCGCTTGTGGCTGGCGTCAGACAGTATGGGCAATGAAGAGTGGCGGCTGTTGCGCCAACTGTTGCTGCAGCATCCGC
TGCAGGGCACGGAATCCTCCCGCCATCATTAA
GTGGCCCAGTGGCAATGTGATTTGCGTGTATCCTGGCGCATGCAGTTGTTTTCTCTGCTGACGCACGGGTTCCTGGTGCT
GATGATCCTGCTGGCTCCCTGGCCGGACGGCTATGCGCCGCTGTGGCTGGGGTTGGTGACGCTGGTGGTGTTCGGTTTCG
TGCGCAGTCAGCGCATCATCAAGTCGCGTCAGGGGGAAATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAGCAGCGT
GACTGGCAGATAGCCCGGCGACCGTGGGTGATGCGCAACGGCGTGTTGCTGTCGTTGCGGGCGACGACCGGTAAAGGGCA
TCAGCGCTTGTGGCTGGCGTCAGACAGTATGGGCAATGAAGAGTGGCGGCTGTTGCGCCAACTGTTGCTGCAGCATCCGC
TGCAGGGCACGGAATCCTCCCGCCATCATTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10544.03 Da Isoelectric Point: 5.5535
>AT81347 WP_023637600.1 NZ_CP023484:720786-721052 [Dickeya sp. Secpp 1600]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT81347 NZ_CP023484:720786-721052 [Dickeya sp. Secpp 1600]
ATGGACATCAATAACAAATCACGCATTCACTGGGCGTGCAGACGCGGAATGCGTGAACTGGATATTTCCATCATGCCGTT
TTTCGAGCATGAGTACGACACGCTGAGCGACGACGACAAGCAGCATTTCATCCGTCTGTTGCAGTGCGACGATCCCGACT
TGTTCAACTGGCTGATGAACCACGGCGAGCCGGTGGATCCGGAACTGAAGCGCATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA
ATGGACATCAATAACAAATCACGCATTCACTGGGCGTGCAGACGCGGAATGCGTGAACTGGATATTTCCATCATGCCGTT
TTTCGAGCATGAGTACGACACGCTGAGCGACGACGACAAGCAGCATTTCATCCGTCTGTTGCAGTGCGACGATCCCGACT
TGTTCAACTGGCTGATGAACCACGGCGAGCCGGTGGATCCGGAACTGAAGCGCATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2K8QJH4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2K8QSU7 |