Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 587161..587945 Replicon chromosome
Accession NZ_CP023484
Organism Dickeya sp. Secpp 1600

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CPA59_RS02745 Protein ID WP_094107695.1
Coordinates 587451..587945 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CPA59_RS02740 Protein ID WP_107758657.1
Coordinates 587161..587454 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPA59_RS02720 583170..584282 + 1113 WP_049854612.1 glycosyltransferase family 4 protein -
CPA59_RS02725 584301..584708 + 408 WP_038917744.1 hypothetical protein -
CPA59_RS02730 584747..586141 + 1395 WP_107758656.1 DUF4832 domain-containing protein -
CPA59_RS02735 586168..586668 + 501 WP_049854610.1 serine acetyltransferase -
CPA59_RS02740 587161..587454 + 294 WP_107758657.1 DUF1778 domain-containing protein Antitoxin
CPA59_RS02745 587451..587945 + 495 WP_094107695.1 GNAT family N-acetyltransferase Toxin
CPA59_RS02750 588068..589339 + 1272 WP_159077918.1 hypothetical protein -
CPA59_RS02755 589343..589879 + 537 WP_107758659.1 hypothetical protein -
CPA59_RS02760 589867..591807 + 1941 WP_107758660.1 hypothetical protein -
CPA59_RS02765 592282..592587 - 306 WP_107758661.1 type II toxin-antitoxin system toxin CcdB -
CPA59_RS02770 592590..592808 - 219 WP_015855076.1 type II toxin-antitoxin system antitoxin CcdA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 586905..596781 9876


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-143)

Antitoxin

Vibrio phage ICP1, Orf50

(4-95)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17640.50 Da        Isoelectric Point: 7.2922

>T81345 WP_094107695.1 NZ_CP023484:587451-587945 [Dickeya sp. Secpp 1600]
MISAPEPLHAEHALSSFCCGVESMDNWLKLRAMKNQVTGASRTFVSCDDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI

Download         Length: 495 bp

>T81345 NZ_CP023484:587451-587945 [Dickeya sp. Secpp 1600]
ATGATCTCTGCTCCTGAGCCACTCCACGCCGAACATGCACTTTCCTCGTTCTGTTGCGGTGTGGAGTCTATGGATAACTG
GCTAAAACTACGGGCGATGAAAAATCAGGTCACTGGAGCATCACGAACTTTCGTCAGTTGCGATGATTCAAAAGTGCTGG
CGTATTACTCATTGGCTTCCAGCGCCGTGGCAACGAATGCCGCTCCCGGACGTTTTCGCCGCAATATGCCCGATCCAATC
CCGGTCGTGGTGCTGGGTCGTCTGGCGGTAGATAAATCATTACATGGTCAGGGTGTTGGCCGGGCGCTGGTACGAGATGC
TGGGCTACGGGTGATTCAGGTGGCGGATACTATCGGCATTCGCGGGATGCTGGTTCATGCGCTGTCTGATGAAGCACGGG
AGTTTTACCTGCGGGTGGGATTTGAGCCTTCGCCGATAGATCCGATGATGCTGATGGTGACGTTGGGGGATTTGGTGGGG
AGTTTATCAATTTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10900.50 Da        Isoelectric Point: 10.1968

>AT81345 WP_107758657.1 NZ_CP023484:587161-587454 [Dickeya sp. Secpp 1600]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQVPSPN
AALRKTMQTPAPWEQKK

Download         Length: 294 bp

>AT81345 NZ_CP023484:587161-587454 [Dickeya sp. Secpp 1600]
ATGCCAGCGACGAACAGCGTTTCTGTTAAACGCGAAACACTAAATTTACGCATCAAGCCTGCCGAACGCGATCTAATCGA
TCGTGCTGCAAAGGCCAGAGGAAAAAATCGTACTGATTTTGTCCTTGAGGCTGCGCGTGCCGCCGCAGAGGAAGCGTTGA
TCGATCAACGCATCATCATGGCAGATCCCGATGCTTATCAGGAATTCCTCGCCCGTTTGGATCAGGTTCCTTCACCGAAT
GCTGCGCTGCGCAAAACCATGCAAACACCTGCACCGTGGGAACAGAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References