Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 587161..587945 | Replicon | chromosome |
Accession | NZ_CP023484 | ||
Organism | Dickeya sp. Secpp 1600 |
Toxin (Protein)
Gene name | TacT2 | Uniprot ID | - |
Locus tag | CPA59_RS02745 | Protein ID | WP_094107695.1 |
Coordinates | 587451..587945 (+) | Length | 165 a.a. |
Antitoxin (Protein)
Gene name | TacA2 | Uniprot ID | - |
Locus tag | CPA59_RS02740 | Protein ID | WP_107758657.1 |
Coordinates | 587161..587454 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CPA59_RS02720 | 583170..584282 | + | 1113 | WP_049854612.1 | glycosyltransferase family 4 protein | - |
CPA59_RS02725 | 584301..584708 | + | 408 | WP_038917744.1 | hypothetical protein | - |
CPA59_RS02730 | 584747..586141 | + | 1395 | WP_107758656.1 | DUF4832 domain-containing protein | - |
CPA59_RS02735 | 586168..586668 | + | 501 | WP_049854610.1 | serine acetyltransferase | - |
CPA59_RS02740 | 587161..587454 | + | 294 | WP_107758657.1 | DUF1778 domain-containing protein | Antitoxin |
CPA59_RS02745 | 587451..587945 | + | 495 | WP_094107695.1 | GNAT family N-acetyltransferase | Toxin |
CPA59_RS02750 | 588068..589339 | + | 1272 | WP_159077918.1 | hypothetical protein | - |
CPA59_RS02755 | 589343..589879 | + | 537 | WP_107758659.1 | hypothetical protein | - |
CPA59_RS02760 | 589867..591807 | + | 1941 | WP_107758660.1 | hypothetical protein | - |
CPA59_RS02765 | 592282..592587 | - | 306 | WP_107758661.1 | type II toxin-antitoxin system toxin CcdB | - |
CPA59_RS02770 | 592590..592808 | - | 219 | WP_015855076.1 | type II toxin-antitoxin system antitoxin CcdA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 586905..596781 | 9876 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 165 a.a. Molecular weight: 17640.50 Da Isoelectric Point: 7.2922
>T81345 WP_094107695.1 NZ_CP023484:587451-587945 [Dickeya sp. Secpp 1600]
MISAPEPLHAEHALSSFCCGVESMDNWLKLRAMKNQVTGASRTFVSCDDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI
MISAPEPLHAEHALSSFCCGVESMDNWLKLRAMKNQVTGASRTFVSCDDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI
Download Length: 495 bp
>T81345 NZ_CP023484:587451-587945 [Dickeya sp. Secpp 1600]
ATGATCTCTGCTCCTGAGCCACTCCACGCCGAACATGCACTTTCCTCGTTCTGTTGCGGTGTGGAGTCTATGGATAACTG
GCTAAAACTACGGGCGATGAAAAATCAGGTCACTGGAGCATCACGAACTTTCGTCAGTTGCGATGATTCAAAAGTGCTGG
CGTATTACTCATTGGCTTCCAGCGCCGTGGCAACGAATGCCGCTCCCGGACGTTTTCGCCGCAATATGCCCGATCCAATC
CCGGTCGTGGTGCTGGGTCGTCTGGCGGTAGATAAATCATTACATGGTCAGGGTGTTGGCCGGGCGCTGGTACGAGATGC
TGGGCTACGGGTGATTCAGGTGGCGGATACTATCGGCATTCGCGGGATGCTGGTTCATGCGCTGTCTGATGAAGCACGGG
AGTTTTACCTGCGGGTGGGATTTGAGCCTTCGCCGATAGATCCGATGATGCTGATGGTGACGTTGGGGGATTTGGTGGGG
AGTTTATCAATTTGA
ATGATCTCTGCTCCTGAGCCACTCCACGCCGAACATGCACTTTCCTCGTTCTGTTGCGGTGTGGAGTCTATGGATAACTG
GCTAAAACTACGGGCGATGAAAAATCAGGTCACTGGAGCATCACGAACTTTCGTCAGTTGCGATGATTCAAAAGTGCTGG
CGTATTACTCATTGGCTTCCAGCGCCGTGGCAACGAATGCCGCTCCCGGACGTTTTCGCCGCAATATGCCCGATCCAATC
CCGGTCGTGGTGCTGGGTCGTCTGGCGGTAGATAAATCATTACATGGTCAGGGTGTTGGCCGGGCGCTGGTACGAGATGC
TGGGCTACGGGTGATTCAGGTGGCGGATACTATCGGCATTCGCGGGATGCTGGTTCATGCGCTGTCTGATGAAGCACGGG
AGTTTTACCTGCGGGTGGGATTTGAGCCTTCGCCGATAGATCCGATGATGCTGATGGTGACGTTGGGGGATTTGGTGGGG
AGTTTATCAATTTGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10900.50 Da Isoelectric Point: 10.1968
>AT81345 WP_107758657.1 NZ_CP023484:587161-587454 [Dickeya sp. Secpp 1600]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQVPSPN
AALRKTMQTPAPWEQKK
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQVPSPN
AALRKTMQTPAPWEQKK
Download Length: 294 bp
>AT81345 NZ_CP023484:587161-587454 [Dickeya sp. Secpp 1600]
ATGCCAGCGACGAACAGCGTTTCTGTTAAACGCGAAACACTAAATTTACGCATCAAGCCTGCCGAACGCGATCTAATCGA
TCGTGCTGCAAAGGCCAGAGGAAAAAATCGTACTGATTTTGTCCTTGAGGCTGCGCGTGCCGCCGCAGAGGAAGCGTTGA
TCGATCAACGCATCATCATGGCAGATCCCGATGCTTATCAGGAATTCCTCGCCCGTTTGGATCAGGTTCCTTCACCGAAT
GCTGCGCTGCGCAAAACCATGCAAACACCTGCACCGTGGGAACAGAAAAAATGA
ATGCCAGCGACGAACAGCGTTTCTGTTAAACGCGAAACACTAAATTTACGCATCAAGCCTGCCGAACGCGATCTAATCGA
TCGTGCTGCAAAGGCCAGAGGAAAAAATCGTACTGATTTTGTCCTTGAGGCTGCGCGTGCCGCCGCAGAGGAAGCGTTGA
TCGATCAACGCATCATCATGGCAGATCCCGATGCTTATCAGGAATTCCTCGCCCGTTTGGATCAGGTTCCTTCACCGAAT
GCTGCGCTGCGCAAAACCATGCAAACACCTGCACCGTGGGAACAGAAAAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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