Detailed information of TA system TA081344

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 425887..426923
• Replicon: chromosome
• Accession: NZ_CP023484
• Organism: Dickeya sp. Secpp 1600

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: CPA59_RS01955
• Protein ID: WP_038917617.1
• Coordinates: 426348..426923 (+)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: CPA59_RS01950
• Protein ID: WP_038917616.1
• Coordinates: 425887..426348 (+)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CPA59_RS01940	421611..421904	+	294	WP_038917614.1	type I-E CRISPR-associated endoribonuclease Cas2	-
CPA59_RS01945	423675..425339	-	1665	WP_107758585.1	MCP four helix bundle domain-containing protein	-
CPA59_RS01950	425887..426348	+	462	WP_038917616.1	helix-turn-helix domain-containing protein	Antitoxin
CPA59_RS01955	426348..426923	+	576	WP_038917617.1	PIN domain-containing protein	Toxin
CPA59_RS01960	427147..427599	+	453	WP_107758586.1	YhbP family protein	-
CPA59_RS01965	427711..428175	-	465	WP_107758587.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
CPA59_RS01970	428274..430412	-	2139	WP_100848752.1	anaerobic ribonucleoside-triphosphate reductase	-
CPA59_RS01975	430792..431700	+	909	WP_107758588.1	homocysteine S-methyltransferase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-115)

Antitoxin

• SinI-like, DNA-binding domain (84-131)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21629.93 Da
• Isoelectric Point: 4.8531

>T81344 WP_038917617.1 NZ_CP023484:426348-426923 [Dickeya sp. Secpp 1600]
MTHTPYPVVLDACVIYPSLLRDLLIHLGLTGLYQPKWTAIIEDEWQRNLLLNRPDLTPEQISRTRELMNQAIPDAMITGF
EALIPGITLPDPDDQHVVAAAIRSNAEIIVTFNLKDFPHPEIDNFGIEALHPDDFITDLLDLNQALVLSAVSRQRHSMRK
PPKSVDEYLDALLRQSLPQTVKELSKFHALI

Nucleotide

• Length: 576 bp

>T81344 NZ_CP023484:426348-426923 [Dickeya sp. Secpp 1600]
ATGACCCATACACCTTATCCTGTCGTGCTAGATGCGTGCGTAATTTATCCATCTCTCCTGCGGGATTTATTAATCCACTT
AGGACTAACAGGGCTGTATCAGCCTAAGTGGACGGCCATCATCGAGGATGAATGGCAACGCAATCTACTGCTGAATAGAC
CTGATTTAACCCCGGAGCAAATCTCGCGGACACGCGAGCTGATGAATCAGGCTATTCCTGATGCGATGATTACTGGGTTT
GAAGCGCTCATTCCAGGCATCACGCTCCCTGATCCTGATGATCAGCATGTGGTTGCAGCCGCCATTCGCAGTAACGCTGA
AATCATCGTTACGTTTAACCTGAAAGATTTTCCCCATCCCGAGATCGATAACTTTGGCATTGAAGCGCTACACCCGGATG
ATTTCATCACAGACCTGCTCGATTTGAATCAGGCGCTTGTGTTATCCGCAGTAAGCAGGCAGCGTCACAGCATGAGAAAA
CCGCCTAAATCGGTTGATGAGTATCTTGATGCGTTACTCCGGCAGAGCTTACCGCAAACAGTAAAAGAATTGAGTAAATT
CCACGCCCTGATTTAG

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 16913.27 Da
• Isoelectric Point: 6.2221

>AT81344 WP_038917616.1 NZ_CP023484:425887-426348 [Dickeya sp. Secpp 1600]
MTNSILDSLSLPAPGEIEAAVRGQRELAAYLSTKMETQKISIQDADNNTRQVELPTSALTLLMSILGELAVGNAVQVVPV
HAELTTQEAANILNVSRPHMVKLLEDGKLPFHKTGRHRRVLFADLMDYKHQRDNESSRAMQALADHSQELGLY

Nucleotide

• Length: 462 bp

>AT81344 NZ_CP023484:425887-426348 [Dickeya sp. Secpp 1600]
ATGACAAACTCAATTCTTGATAGCCTGAGCCTTCCGGCACCAGGGGAGATTGAGGCGGCTGTTCGTGGACAAAGGGAGCT
TGCTGCCTATCTCTCCACAAAGATGGAAACACAAAAAATCTCGATTCAGGACGCAGATAACAACACTCGTCAGGTCGAAT
TACCGACGTCGGCACTGACATTATTGATGTCGATTTTAGGCGAGCTGGCTGTGGGTAACGCGGTTCAGGTTGTTCCTGTT
CATGCTGAATTAACGACACAGGAGGCAGCCAACATTCTGAATGTTTCACGCCCTCACATGGTGAAGCTTCTGGAGGATGG
GAAACTACCTTTTCATAAAACCGGTCGCCACCGCCGTGTGCTTTTCGCTGACCTGATGGACTATAAACACCAGAGGGATA
ATGAAAGCAGTAGAGCAATGCAGGCGTTGGCAGATCATAGCCAAGAGCTTGGATTGTACTAA