Detailed information of TA system TA081340

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): spoIISABC/SpoIISA-SpoIISB
• Location: 4494288..4495207
• Replicon: chromosome
• Accession: NZ_CP023481
• Organism: Bacillus glycinifermentans strain KBN06P03352

Toxin (Protein)

• Gene name: spoIISA
• Uniprot ID: -
• Locus tag: COP00_RS23700
• Protein ID: WP_048355864.1
• Coordinates: 4494461..4495207 (-)
• Length: 249 a.a.

Antitoxin (Protein)

• Gene name: spoIISB
• Uniprot ID: -
• Locus tag: COP00_RS23695
• Protein ID: WP_048355877.1
• Coordinates: 4494288..4494461 (-)
• Length: 58 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
COP00_RS23675	4489514..4490362	+	849	WP_048355863.1	SDR family oxidoreductase	-
COP00_RS23680	4490376..4491394	+	1019	Protein_4590	zinc-binding alcohol dehydrogenase family protein	-
COP00_RS23690	4492718..4493986	+	1269	WP_048407087.1	MFS transporter	-
COP00_RS23695	4494288..4494461	-	174	WP_048355877.1	type II toxin-antitoxin system SpoIISB family antitoxin	Antitoxin
COP00_RS23700	4494461..4495207	-	747	WP_048355864.1	type II toxin-antitoxin system SpoIISA family toxin	Toxin
COP00_RS23705	4495324..4496322	-	999	WP_048355865.1	inorganic phosphate transporter	-
COP00_RS23710	4496335..4496952	-	618	WP_006638544.1	DUF47 domain-containing protein	-
COP00_RS23715	4497253..4499013	+	1761	WP_048355866.1	gamma-glutamyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SpoIISA, type II toxin-antitoxin system (3-238)

Antitoxin

• Antitoxin SpoIISB (1-57)

Sequences

Toxin

Protein

• Length: 249 a.a.
• Molecular weight: 29631.03 Da
• Isoelectric Point: 4.6123

>T81340 WP_048355864.1 NZ_CP023481:c4495207-4494461 [Bacillus glycinifermentans]
MLLFYQFSVWVIVLALALYVFAVWRFEKKMKEKTIAIRKTWYLLYVIGAALYWTYDPQSIFSNWLHYLIVAVFFTLTDAF
IFLNAYFKKLGTNELATDTRELLEENNDLLHTYQNRLKTYQYLLKNEPIHIYYGDIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSNESKDHLLEHMENRFAVQEKLDRKDVYYEENGKMVLIPFSIHEYDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDE

Nucleotide

• Length: 747 bp

>T81340 NZ_CP023481:c4495207-4494461 [Bacillus glycinifermentans]
ATGCTGCTTTTTTATCAGTTTTCAGTCTGGGTGATCGTCCTCGCCTTAGCCTTGTACGTTTTTGCCGTCTGGCGTTTTGA
AAAAAAGATGAAAGAAAAAACGATCGCGATCCGGAAAACGTGGTATCTCCTTTATGTGATCGGCGCCGCGCTTTACTGGA
CGTACGATCCCCAATCCATTTTCAGCAATTGGCTCCATTACTTAATCGTCGCCGTCTTTTTCACGCTGACCGATGCGTTT
ATTTTCTTAAACGCCTACTTCAAAAAGCTCGGCACGAACGAATTGGCCACAGACACAAGAGAACTTCTTGAAGAAAACAA
CGACCTGCTTCACACGTATCAAAACAGGCTCAAAACGTACCAATACCTATTGAAAAACGAACCGATCCACATCTACTATG
GAGATATAGAAGCTTACGCTGAAGGCATTGAAAAACTCATCAAACGGTTTGCCGAAAAAATGAATATATCCGCCGCACTA
TGCGAATATAATTCGAACGAGAGCAAAGATCATTTGCTCGAACATATGGAAAACCGTTTCGCTGTTCAGGAAAAGCTGGA
CCGGAAAGACGTGTATTACGAAGAAAACGGAAAAATGGTCCTGATTCCATTTTCGATCCATGAATACGACTATGTGATGA
AACTGACATCCGAGGACCTTGTCACTGAATTTGATTATCTGCTGTTTACTTCTTTAACCAGCATCTATGATCTTCTGCTA
CCAAACGAAGAGGAAGGTGACGAATGA

Antitoxin

Protein

• Length: 58 a.a.
• Molecular weight: 6796.75 Da
• Isoelectric Point: 10.6588

>AT81340 WP_048355877.1 NZ_CP023481:c4494461-4494288 [Bacillus glycinifermentans]
MEPVFQQDKDRSTGRGTCKVFKKQSKTHIAKYEVSPHTERIFRQNARLIDEYKRKNA

Nucleotide

• Length: 174 bp

>AT81340 NZ_CP023481:c4494461-4494288 [Bacillus glycinifermentans]
ATGGAACCGGTTTTTCAGCAAGACAAAGACCGTTCAACGGGGCGCGGCACATGTAAAGTATTCAAAAAACAATCAAAAAC
CCACATCGCCAAATATGAGGTCAGCCCACACACCGAACGGATTTTCAGGCAAAATGCCCGGCTGATCGATGAGTATAAAC
GAAAAAATGCCTGA