Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910012..1910159 Replicon chromosome
Accession NZ_CP023478
Organism Klebsiella quasipneumoniae strain KPC142

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910053..1910155 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910012..1910159 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPC142_RS09560 1905147..1907207 + 2061 WP_004203388.1 oligopeptidase B -
KPC142_RS09565 1907211..1907870 - 660 WP_004203387.1 exodeoxyribonuclease X -
KPC142_RS09570 1907949..1908179 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KPC142_RS09575 1908292..1908666 + 375 WP_106938921.1 CopC domain-containing protein YobA -
KPC142_RS09580 1908670..1909539 + 870 WP_106938922.1 copper homeostasis membrane protein CopD -
KPC142_RS09585 1909556..1909894 + 339 WP_002911404.1 YebY family protein -
- 1910012..1910159 - 148 - - Antitoxin
- 1910053..1910155 + 103 - - Toxin
KPC142_RS27125 1910552..1910695 - 144 WP_032425946.1 Ecr family regulatory small membrane protein -
KPC142_RS09595 1910799..1911767 - 969 WP_117124423.1 VirK/YbjX family protein -
KPC142_RS09600 1911924..1912577 + 654 WP_023318613.1 protein-serine/threonine phosphatase -
KPC142_RS09605 1912574..1912765 - 192 WP_002911395.1 YebW family protein -
KPC142_RS09610 1912863..1913102 - 240 WP_002911393.1 YebV family protein -
KPC142_RS09615 1913219..1914652 - 1434 WP_106938923.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T81325 NZ_CP023478:1910053-1910155 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT81325 NZ_CP023478:c1910159-1910012 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References