Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /GNAT-DUF1778 |
| Location | 2053765..2054531 | Replicon | chromosome |
| Accession | NZ_CP023472 | ||
| Organism | Vibrio parahaemolyticus strain FORC_072 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A432DAA5 |
| Locus tag | FORC72_RS11025 | Protein ID | WP_017053840.1 |
| Coordinates | 2054034..2054531 (+) | Length | 166 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | FORC72_RS11020 | Protein ID | WP_120458926.1 |
| Coordinates | 2053765..2054037 (+) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FORC72_RS10985 | 2050361..2050708 | - | 348 | WP_120458924.1 | hypothetical protein | - |
| FORC72_RS10990 | 2050866..2051360 | - | 495 | WP_120458925.1 | hypothetical protein | - |
| FORC72_RS10995 | 2051524..2052396 | - | 873 | WP_042773052.1 | hypothetical protein | - |
| FORC72_RS11000 | 2052601..2052975 | - | 375 | WP_025507097.1 | hypothetical protein | - |
| FORC72_RS11005 | 2053018..2053110 | - | 93 | WP_079765073.1 | DUF3265 domain-containing protein | - |
| FORC72_RS11010 | 2053125..2053535 | - | 411 | WP_021448800.1 | hypothetical protein | - |
| FORC72_RS26355 | 2053563..2053655 | - | 93 | WP_079741491.1 | DUF3265 domain-containing protein | - |
| FORC72_RS11020 | 2053765..2054037 | + | 273 | WP_120458926.1 | DUF1778 domain-containing protein | Antitoxin |
| FORC72_RS11025 | 2054034..2054531 | + | 498 | WP_017053840.1 | GNAT family N-acetyltransferase | Toxin |
| FORC72_RS11030 | 2054565..2054657 | - | 93 | WP_205570799.1 | DUF3265 domain-containing protein | - |
| FORC72_RS11035 | 2055111..2055203 | - | 93 | WP_120458928.1 | DUF3265 domain-containing protein | - |
| FORC72_RS11040 | 2055229..2055573 | - | 345 | WP_120458929.1 | hypothetical protein | - |
| FORC72_RS11045 | 2055673..2056119 | - | 447 | WP_120458930.1 | hypothetical protein | - |
| FORC72_RS11050 | 2056360..2057322 | + | 963 | WP_029852815.1 | integron integrase | - |
| FORC72_RS11055 | 2057373..2057846 | - | 474 | WP_005458833.1 | DUF2947 domain-containing protein | - |
| FORC72_RS11060 | 2057860..2058456 | - | 597 | WP_120458931.1 | HD domain-containing protein | - |
| FORC72_RS11065 | 2058458..2059042 | - | 585 | WP_005458831.1 | ribosomal protein S5-alanine N-acetyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 1818293..2129287 | 310994 | |
| - | inside | Integron | - | - | 1917746..2057322 | 139576 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 166 a.a. Molecular weight: 18458.12 Da Isoelectric Point: 8.8085
>T81316 WP_017053840.1 NZ_CP023472:2054034-2054531 [Vibrio parahaemolyticus]
MMNTVLLDKAKHDRNRFNCGIEALNNYLKVMASQQAKKDNTRTFVLEDDSDNSHVIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKHFYERYGFQAFQDAENKLFITIADV
RASLG
MMNTVLLDKAKHDRNRFNCGIEALNNYLKVMASQQAKKDNTRTFVLEDDSDNSHVIGFYTLTMTPIDLKALPDKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWLLIDALRKLLAASDSVAFPVVIVDAKDGAKHFYERYGFQAFQDAENKLFITIADV
RASLG
Download Length: 498 bp
>T81316 NZ_CP023472:2054034-2054531 [Vibrio parahaemolyticus]
ATGATGAATACGGTACTTCTAGATAAAGCTAAACACGATAGAAACCGATTCAACTGTGGCATCGAAGCTCTCAATAATTA
CTTAAAAGTAATGGCGAGTCAGCAAGCAAAGAAGGACAACACCAGAACGTTTGTTTTGGAAGATGATAGCGACAACTCAC
ATGTTATCGGCTTTTACACGCTAACAATGACACCAATTGACTTAAAGGCATTGCCTGATAAGTTACAAAAAAAGCACCAA
TCATCCACCTCTGGTGGTCTGATTGCCCGCCTTGCTGTCGATGACCGATACAAAGGGAAAGGATTTGGTGAGTGGCTGCT
TATCGACGCACTCAGAAAGCTATTAGCCGCTAGTGATAGCGTTGCATTTCCAGTTGTTATCGTTGATGCCAAAGACGGAG
CAAAACATTTCTATGAACGCTATGGTTTTCAAGCATTTCAAGATGCCGAAAACAAACTCTTCATCACCATTGCAGATGTA
AGAGCAAGCTTAGGCTAG
ATGATGAATACGGTACTTCTAGATAAAGCTAAACACGATAGAAACCGATTCAACTGTGGCATCGAAGCTCTCAATAATTA
CTTAAAAGTAATGGCGAGTCAGCAAGCAAAGAAGGACAACACCAGAACGTTTGTTTTGGAAGATGATAGCGACAACTCAC
ATGTTATCGGCTTTTACACGCTAACAATGACACCAATTGACTTAAAGGCATTGCCTGATAAGTTACAAAAAAAGCACCAA
TCATCCACCTCTGGTGGTCTGATTGCCCGCCTTGCTGTCGATGACCGATACAAAGGGAAAGGATTTGGTGAGTGGCTGCT
TATCGACGCACTCAGAAAGCTATTAGCCGCTAGTGATAGCGTTGCATTTCCAGTTGTTATCGTTGATGCCAAAGACGGAG
CAAAACATTTCTATGAACGCTATGGTTTTCAAGCATTTCAAGATGCCGAAAACAAACTCTTCATCACCATTGCAGATGTA
AGAGCAAGCTTAGGCTAG
Antitoxin
Download Length: 91 a.a. Molecular weight: 9716.18 Da Isoelectric Point: 7.0109
>AT81316 WP_120458926.1 NZ_CP023472:2053765-2054037 [Vibrio parahaemolyticus]
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQALKLSQADAMLLMEALDHPATQNSKLKA
AADRYESKTQ
MATTLPRITARVDVDTQDLLTKAAAIAGMSSINSFVLSAAIEKAKQVIEREQALKLSQADAMLLMEALDHPATQNSKLKA
AADRYESKTQ
Download Length: 273 bp
>AT81316 NZ_CP023472:2053765-2054037 [Vibrio parahaemolyticus]
ATGGCTACTACTTTGCCTCGCATCACCGCTAGAGTTGATGTCGATACACAAGACTTACTTACTAAGGCTGCCGCGATCGC
CGGCATGTCTAGCATCAACTCGTTTGTTCTAAGCGCTGCAATCGAAAAGGCTAAACAAGTCATCGAACGTGAACAGGCTT
TAAAACTGAGCCAAGCAGATGCGATGTTGCTCATGGAGGCTTTAGATCATCCTGCAACACAGAACTCAAAACTAAAAGCT
GCTGCTGATCGATACGAGAGCAAAACTCAATGA
ATGGCTACTACTTTGCCTCGCATCACCGCTAGAGTTGATGTCGATACACAAGACTTACTTACTAAGGCTGCCGCGATCGC
CGGCATGTCTAGCATCAACTCGTTTGTTCTAAGCGCTGCAATCGAAAAGGCTAAACAAGTCATCGAACGTGAACAGGCTT
TAAAACTGAGCCAAGCAGATGCGATGTTGCTCATGGAGGCTTTAGATCATCCTGCAACACAGAACTCAAAACTAAAAGCT
GCTGCTGATCGATACGAGAGCAAAACTCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|