Detailed information of TA system TA081312

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 62319..62878
• Replicon: plasmid pSalSendai
• Accession: NZ_CP023471
• Organism: Salmonella enterica subsp. enterica strain BAA-1672

Toxin (Protein)

• Gene name: relE
• Uniprot ID: S1PMX5
• Locus tag: CO195_RS23400
• Protein ID: WP_000421257.1
• Coordinates: 62319..62594 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CO195_RS23405
• Protein ID: WP_115376289.1
• Coordinates: 62594..62878 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CO195_RS23340	57572..58378	-	807	WP_117335825.1	site-specific integrase	-
CO195_RS23345	58379..58684	-	306	WP_001159866.1	type II toxin-antitoxin system toxin CcdB	-
CO195_RS23350	58686..58904	-	219	WP_000813634.1	type II toxin-antitoxin system antitoxin CcdA	-
CO195_RS23365	59488..59718	+	231	WP_001261287.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
CO195_RS23370	59715..60131	+	417	WP_001044768.1	type II toxin-antitoxin system VapC family toxin	-
CO195_RS23380	60522..60845	+	324	Protein_75	hypothetical protein	-
CO195_RS23650	61147..61485	-	339	WP_162887451.1	hypothetical protein	-
CO195_RS23395	61995..62213	-	219	WP_048889380.1	hypothetical protein	-
CO195_RS23400	62319..62594	-	276	WP_000421257.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CO195_RS23405	62594..62878	-	285	WP_115376289.1	ribbon-helix-helix protein, CopG family	Antitoxin
CO195_RS23415	64148..64417	-	270	WP_048889368.1	hypothetical protein	-
CO195_RS23750	64517..64755	+	239	Protein_81	IS3 family transposase	-
CO195_RS23425	65005..65643	-	639	WP_115376291.1	ParB N-terminal domain-containing protein	-
CO195_RS23430	65628..66854	-	1227	WP_048889365.1	phosphoadenosine phosphosulfate reductase	-
CO195_RS23435	67074..67460	-	387	WP_052747567.1	helix-turn-helix domain-containing protein	-
CO195_RS23440	67471..67788	-	318	WP_048889364.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..81125	81125

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 13558.26 Da
• Isoelectric Point: 5.5500

>T81312 WP_000421257.1 NZ_CP023471:c62594-62319 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFF

Nucleotide

• Length: 276 bp

>T81312 NZ_CP023471:c62594-62319 [Salmonella enterica subsp. enterica]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 13999.79 Da
• Isoelectric Point: 5.5500

>AT81312 WP_115376289.1 NZ_CP023471:c62878-62594 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF

Nucleotide

• Length: 285 bp

>AT81312 NZ_CP023471:c62878-62594 [Salmonella enterica subsp. enterica]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Toxin

• AlphaFold DB: S1PMX5