Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
| Location | 58379..58904 | Replicon | plasmid pSalSendai |
| Accession | NZ_CP023471 | ||
| Organism | Salmonella enterica subsp. enterica strain BAA-1672 | ||
Toxin (Protein)
| Gene name | ccdB | Uniprot ID | - |
| Locus tag | CO195_RS23345 | Protein ID | WP_001159866.1 |
| Coordinates | 58379..58684 (-) | Length | 102 a.a. |
Antitoxin (Protein)
| Gene name | ccdA | Uniprot ID | S1PPD8 |
| Locus tag | CO195_RS23350 | Protein ID | WP_000813634.1 |
| Coordinates | 58686..58904 (-) | Length | 73 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CO195_RS23300 | 53804..54016 | + | 213 | WP_000402944.1 | hypothetical protein | - |
| CO195_RS23305 | 54189..54440 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| CO195_RS23310 | 54437..54724 | + | 288 | WP_001270421.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CO195_RS23315 | 54738..54986 | + | 249 | Protein_66 | hypothetical protein | - |
| CO195_RS23320 | 55011..55301 | + | 291 | WP_048889372.1 | hypothetical protein | - |
| CO195_RS23330 | 55943..56920 | + | 978 | WP_048889370.1 | RepB family plasmid replication initiator protein | - |
| CO195_RS23335 | 57181..57381 | - | 201 | Protein_69 | hypothetical protein | - |
| CO195_RS23340 | 57572..58378 | - | 807 | WP_117335825.1 | site-specific integrase | - |
| CO195_RS23345 | 58379..58684 | - | 306 | WP_001159866.1 | type II toxin-antitoxin system toxin CcdB | Toxin |
| CO195_RS23350 | 58686..58904 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin |
| CO195_RS23365 | 59488..59718 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| CO195_RS23370 | 59715..60131 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | - |
| CO195_RS23380 | 60522..60845 | + | 324 | Protein_75 | hypothetical protein | - |
| CO195_RS23650 | 61147..61485 | - | 339 | WP_162887451.1 | hypothetical protein | - |
| CO195_RS23395 | 61995..62213 | - | 219 | WP_048889380.1 | hypothetical protein | - |
| CO195_RS23400 | 62319..62594 | - | 276 | WP_000421257.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| CO195_RS23405 | 62594..62878 | - | 285 | WP_115376289.1 | ribbon-helix-helix protein, CopG family | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..81125 | 81125 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 15030.03 Da Isoelectric Point: 5.5500
>T81310 WP_001159866.1 NZ_CP023471:c58684-58379 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
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FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF
Download Length: 306 bp
>T81310 NZ_CP023471:c58684-58379 [Salmonella enterica subsp. enterica]
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Antitoxin
Download Length: 73 a.a. Molecular weight: 10761.91 Da Isoelectric Point: 5.5500
>AT81310 WP_000813634.1 NZ_CP023471:c58904-58686 [Salmonella enterica subsp. enterica]
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Download Length: 219 bp
>AT81310 NZ_CP023471:c58904-58686 [Salmonella enterica subsp. enterica]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|