Detailed information of TA system TA081308

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 40906..41431
• Replicon: plasmid pSalMiami
• Accession: NZ_CP023469
• Organism: Salmonella enterica subsp. enterica strain BAA-1586

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: A0A5J1SSZ4
• Locus tag: COO54_RS23750
• Protein ID: WP_001159865.1
• Coordinates: 41126..41431 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: COO54_RS23745
• Protein ID: WP_079953237.1
• Coordinates: 40906..41124 (+)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
COO54_RS23725	35976..36937	+	962	Protein_39	ISNCY family transposase	-
COO54_RS23730	37448..38116	+	669	WP_085376314.1	site-specific integrase	-
COO54_RS23735	38424..39413	-	990	WP_085376335.1	RepB family plasmid replication initiator protein	-
COO54_RS23740	39906..40178	-	273	Protein_42	polysaccharide deacetylase family protein	-
COO54_RS23745	40906..41124	+	219	WP_079953237.1	type II toxin-antitoxin system antitoxin CcdA	Antitoxin
COO54_RS23750	41126..41431	+	306	WP_001159865.1	type II toxin-antitoxin system toxin CcdB	Toxin
COO54_RS23755	41433..41723	+	291	WP_085376312.1	cytoplasmic protein	-
COO54_RS23760	41720..42256	+	537	Protein_46	cytoplasmic protein	-
COO54_RS23765	42269..43051	+	783	WP_079953235.1	site-specific integrase	-
COO54_RS23770	43201..44130	-	930	WP_057394647.1	Rpn family recombination-promoting nuclease/putative transposase	-
COO54_RS23775	44545..45750	+	1206	WP_117338880.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..94044	94044

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 13091.77 Da
• Isoelectric Point: 12.8043

>T81308 WP_001159865.1 NZ_CP023469:41126-41431 [Salmonella enterica subsp. enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 306 bp

>T81308 NZ_CP023469:41126-41431 [Salmonella enterica subsp. enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 9374.72 Da
• Isoelectric Point: 12.6573

>AT81308 WP_079953237.1 NZ_CP023469:40906-41124 [Salmonella enterica subsp. enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 219 bp

>AT81308 NZ_CP023469:40906-41124 [Salmonella enterica subsp. enterica]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Structures

Toxin

• AlphaFold DB: A0A5J1SSZ4