Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 2789003..2789598 Replicon chromosome
Accession NZ_CP023467
Organism Dickeya dadantii strain DSM 18020

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag CO076_RS12665 Protein ID WP_038911308.1
Coordinates 2789003..2789380 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag CO076_RS12670 Protein ID WP_038911309.1
Coordinates 2789377..2789598 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO076_RS12640 2785070..2785960 - 891 WP_038911305.1 oxidoreductase -
CO076_RS12645 2786091..2786714 - 624 WP_038911306.1 glutathione S-transferase family protein -
CO076_RS12650 2786973..2787239 + 267 WP_022633797.1 hypothetical protein -
CO076_RS12655 2787502..2787933 - 432 WP_038911307.1 VOC family protein -
CO076_RS12660 2788065..2788649 + 585 WP_038902688.1 TetR/AcrR family transcriptional regulator -
CO076_RS12665 2789003..2789380 - 378 WP_038911308.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
CO076_RS12670 2789377..2789598 - 222 WP_038911309.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CO076_RS12675 2789738..2790886 - 1149 WP_038901367.1 L-threonine dehydrogenase -
CO076_RS12680 2791257..2791727 + 471 WP_107768306.1 NUDIX domain-containing protein -
CO076_RS12685 2791799..2792476 - 678 WP_038901368.1 respiratory nitrate reductase subunit gamma -
CO076_RS12690 2792476..2793195 - 720 WP_013318182.1 nitrate reductase molybdenum cofactor assembly chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14304.44 Da        Isoelectric Point: 5.2155

>T81306 WP_038911308.1 NZ_CP023467:c2789380-2789003 [Dickeya dadantii]
MKWVSAQDVIDFHDRILQVLPGVAGMADPGRAEALIYRVQNRLYYEGVTELFELAATYWVTIARGHIFNDDNKRTAFFVT
MIFLRRNGILIVDNDNSLEELTIKAATGECLVSELAEQLRKRVEK

Download         Length: 378 bp

>T81306 NZ_CP023467:c2789380-2789003 [Dickeya dadantii]
ATGAAATGGGTGAGTGCACAGGACGTCATCGACTTTCATGATCGTATTTTGCAGGTGTTGCCCGGGGTAGCGGGTATGGC
TGATCCTGGTCGGGCTGAGGCGTTGATTTATCGGGTGCAAAACCGTCTTTATTATGAAGGTGTGACCGAATTGTTTGAGC
TGGCGGCGACGTATTGGGTAACCATTGCTCGTGGTCATATTTTTAATGATGACAATAAACGCACCGCTTTTTTTGTTACC
ATGATATTTTTACGCCGCAATGGCATATTGATTGTTGATAACGACAATTCGCTGGAAGAACTCACCATTAAGGCGGCAAC
CGGAGAATGCCTGGTGTCGGAACTCGCCGAACAATTAAGAAAACGGGTGGAAAAATAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8237.36 Da        Isoelectric Point: 7.2021

>AT81306 WP_038911309.1 NZ_CP023467:c2789598-2789377 [Dickeya dadantii]
MKTYTITEARQNIATVIDTAASGEPVEIKRRDGTSTVLIPKAEFEAYQKARLDAEFDFIMQRHGHTIKALADR

Download         Length: 222 bp

>AT81306 NZ_CP023467:c2789598-2789377 [Dickeya dadantii]
ATGAAGACTTATACCATTACTGAAGCCCGGCAAAACATTGCGACGGTCATTGATACAGCAGCCAGCGGTGAGCCGGTAGA
GATTAAGCGTCGGGACGGCACCTCGACTGTACTCATCCCCAAAGCAGAGTTTGAGGCTTATCAGAAAGCCAGATTAGACG
CCGAATTTGATTTCATCATGCAGCGCCACGGACACACCATCAAAGCGCTTGCTGACAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References