Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 733197..733875 Replicon chromosome
Accession NZ_CP023467
Organism Dickeya dadantii strain DSM 18020

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag CO076_RS03500 Protein ID WP_038910244.1
Coordinates 733444..733875 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag CO076_RS03495 Protein ID WP_013316361.1
Coordinates 733197..733463 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO076_RS03475 729645..730295 + 651 WP_038910242.1 LysE family translocator -
CO076_RS03480 730365..730973 - 609 WP_013316358.1 HD domain-containing protein -
CO076_RS03485 731182..731832 + 651 WP_038900288.1 hemolysin III family protein -
CO076_RS03490 731905..732885 - 981 WP_038910243.1 tRNA-modifying protein YgfZ -
CO076_RS03495 733197..733463 + 267 WP_013316361.1 FAD assembly factor SdhE Antitoxin
CO076_RS03500 733444..733875 + 432 WP_038910244.1 protein YgfX Toxin
CO076_RS03505 733972..734490 - 519 WP_038910245.1 flavodoxin FldB -
CO076_RS03510 734619..735944 - 1326 WP_038910246.1 MHS family MFS transporter -
CO076_RS03515 736207..737106 + 900 WP_013316366.1 site-specific tyrosine recombinase XerD -
CO076_RS03520 737195..737911 + 717 WP_013316367.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16838.58 Da        Isoelectric Point: 10.9658

>T81294 WP_038910244.1 NZ_CP023467:733444-733875 [Dickeya dadantii]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVFSQRIIKTRQGEISLHGENQLHWQKR
DWQIVRRPWLMRNGVLLSLRAVDGKGHQRLWLASDSMGNEEWRLLRQLLQQHSLQGTESSHHH

Download         Length: 432 bp

>T81294 NZ_CP023467:733444-733875 [Dickeya dadantii]
GTGGCCCAGTGGCAATGTGATTTACGCGTATCCTGGCGCATGCAGCTGTTTTCGCTGCTGACGCACGGGTTTCTGGTGCT
GATGATCCTGCTGGCCCCCTGGCCGGACGGCTATGCGCCGCTGTGGCTGGGGCTGGTGACGCTGGTGGTGTTCGGTTTTG
TGTTCAGCCAGCGCATCATCAAGACGCGTCAGGGGGAGATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAGAAGCGT
GACTGGCAGATAGTCCGGCGGCCGTGGCTGATGCGCAACGGCGTGTTGCTGTCATTGCGGGCGGTGGATGGCAAAGGGCA
TCAACGCCTGTGGCTGGCGTCTGACAGTATGGGAAACGAAGAGTGGCGGCTGTTGCGCCAACTGCTGCAGCAGCATTCGC
TGCAGGGAACGGAATCCTCCCACCATCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10476.98 Da        Isoelectric Point: 5.5981

>AT81294 WP_013316361.1 NZ_CP023467:733197-733463 [Dickeya dadantii]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQQFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT81294 NZ_CP023467:733197-733463 [Dickeya dadantii]
ATGGACATCAATAACAAATCACGTATTCACTGGGCGTGCAGACGCGGAATGCGTGAACTGGATATCTCCATCATGCCGTT
TTTCGAGCATGAGTACGACACGCTGAGCGACGACGACAAGCAGCAGTTCATCCGTCTGTTGCAGTGCGACGATCCCGACT
TGTTCAACTGGTTGATGAACCATGGCGAGCCGGTGGATCCGGCGCTGAAACGCATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References