Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 600817..601601 Replicon chromosome
Accession NZ_CP023467
Organism Dickeya dadantii strain DSM 18020

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CO076_RS02855 Protein ID WP_038910183.1
Coordinates 601107..601601 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CO076_RS02850 Protein ID WP_038910182.1
Coordinates 600817..601110 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CO076_RS02810 595989..596396 + 408 WP_013316234.1 hypothetical protein -
CO076_RS02815 596435..597829 + 1395 WP_038910178.1 DUF4832 domain-containing protein -
CO076_RS02820 597856..598356 + 501 WP_038910179.1 serine acetyltransferase -
CO076_RS02825 598253..598597 - 345 Protein_536 CcdB family protein -
CO076_RS02830 598609..598710 - 102 Protein_537 type II toxin-antitoxin system CcdA family antitoxin -
CO076_RS02835 599184..599675 - 492 WP_038910180.1 hypothetical protein -
CO076_RS02850 600817..601110 + 294 WP_038910182.1 DUF1778 domain-containing protein Antitoxin
CO076_RS02855 601107..601601 + 495 WP_038910183.1 GNAT family N-acetyltransferase Toxin
CO076_RS02865 603054..604316 - 1263 WP_038910185.1 integrase arm-type DNA-binding domain-containing protein -
CO076_RS02875 604716..605291 - 576 WP_038900225.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17672.54 Da        Isoelectric Point: 7.7788

>T81293 WP_038910183.1 NZ_CP023467:601107-601601 [Dickeya dadantii]
MISAPEPLRAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
GLSI

Download         Length: 495 bp

>T81293 NZ_CP023467:601107-601601 [Dickeya dadantii]
ATGATTTCCGCCCCTGAGCCACTCCGCGCCGAACATGTACTATCTTCATTCTGTTGCGGCGTGGAGTCTATGGACAACTG
GCTGAAGCAACGGGCGATGAAAAATCAGGTCACTGGTGCATCACGAACTTTCGTCAGTTGCGATGATTCAAAAGTGTTGG
CGTATTATTCATTGGCCTCCAGCGCTGTAGCAACGAATGCCGCTCCTGGACGTTTTCGCCGCAATATGCCCGATCCAATC
CCGGTCGTGGTGCTGGGTCGTCTGGCGGTAGATAAATCATTACATGGTCAGGGTGTTGGCCGGGCGCTGGTACGAGATGC
TGGGCTACGGGTGATTCAGGTGGCGGATACTATCGGCATTCGCGGGATGTTGGTTCATGCGCTGTCTGATGAAGCGCGGG
AATTTTACCTACGTGTGGGGTTTGAGCCTTCACCGATAGATCCGATGATGCTGATGGTGACGCTGGGGGATTTGGTGGGG
GGGTTATCAATTTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10934.51 Da        Isoelectric Point: 10.1968

>AT81293 WP_038910182.1 NZ_CP023467:600817-601110 [Dickeya dadantii]
MPVTNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQTTSPN
AALRKTMQTPAPWEQKK

Download         Length: 294 bp

>AT81293 NZ_CP023467:600817-601110 [Dickeya dadantii]
ATGCCAGTTACGAACAGCGTTTCTGTTAAACGCGAAACATTGAATTTACGCATCAAGCCTGCCGAACGCGATCTGATTGA
TCGTGCTGCGAAGGCCAGAGGAAAAAATCGTACTGATTTTGTCCTTGAGGCTGCGCGTGCCGCCGCAGAGGAAGCGTTGA
TCGATCAGCGCATCATCATGGCAGATCCTGATGCTTATCAGGAATTCCTTGCTCGTCTGGATCAGACTACTTCACCAAAT
GCCGCGCTGCGAAAAACCATGCAAACTCCTGCACCGTGGGAACAGAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References