Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 460620..461362 Replicon chromosome
Accession NZ_CP023467
Organism Dickeya dadantii strain DSM 18020

Toxin (Protein)


Gene name ataT Uniprot ID E0SIC1
Locus tag CO076_RS02145 Protein ID WP_013316117.1
Coordinates 460620..461099 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID E0SJ01
Locus tag CO076_RS02150 Protein ID WP_013316118.1
Coordinates 461090..461362 (-) Length 91 a.a.

Genomic Context

CO076_RS02125CO076_RS02130CO076_RS02135CO076_RS02160CO076_RS02165CO076_RS02170CO076_RS02140CO076_RS02145CO076_RS02150
Location: 455710..456978 (1269 bp)
Type: Others
Protein ID: WP_038910093.1
Location: 457077..458294 (1218 bp)
Type: Others
Protein ID: WP_038910094.1
Location: 458338..459966 (1629 bp)
Type: Others
Protein ID: WP_038910095.1
Location: 461852..462310 (459 bp)
Type: Others
Protein ID: Protein_406
Location: 462337..463194 (858 bp)
Type: Others
Protein ID: WP_038910100.1
Location: 463768..465942 (2175 bp)
Type: Others
Protein ID: WP_159077855.1
Location: 460190..460591 (402 bp)
Type: Others
Protein ID: WP_038910096.1
Location: 460620..461099 (480 bp)
Type: Toxin
Protein ID: WP_013316117.1
Location: 461090..461362 (273 bp)
Type: Antitoxin
Protein ID: WP_013316118.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CO076_RS02125455710..456978+1269WP_038910093.1integrase arm-type DNA-binding domain-containing protein-
CO076_RS02130457077..458294+1218WP_038910094.1dNTP triphosphohydrolase-
CO076_RS02135458338..459966+1629WP_038910095.1TIGR04141 family sporadically distributed protein-
CO076_RS02140460190..460591-402WP_038910096.1hypothetical protein-
CO076_RS02145460620..461099-480WP_013316117.1GNAT family N-acetyltransferaseToxin
CO076_RS02150461090..461362-273WP_013316118.1DUF1778 domain-containing proteinAntitoxin
CO076_RS02160461852..462310+459Protein_406integrase family protein-
CO076_RS02165462337..463194+858WP_038910100.1hypothetical protein-
CO076_RS02170463768..465942+2175WP_159077855.1sigma-70 family RNA polymerase sigma factor-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-147)

Antitoxin

Vibrio phage ICP1, Orf50

(10-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17564.34 Da        Isoelectric Point: 9.5367

>T81292 WP_013316117.1 NZ_CP023467:c461099-460620 [Dickeya dadantii]
VGITAPELLLPQHAVVDFHCSEPSLNEWLKRKALKNQTLGASRTFVVCEAGTQRVVGFYALASGSIQRQVAPGAFRRNMP
DPIPVLVLGRLAVDERYQRMGIGAGLLKDAVLRSRNVAQQVGNKALLVHALSDEAKAFYQYWGFVPSEIQEHTLLLSLW

Download         Length: 480 bp

>T81292 NZ_CP023467:c461099-460620 [Dickeya dadantii]
GTGGGAATAACGGCACCTGAATTATTGCTGCCTCAACATGCAGTTGTGGATTTTCATTGTTCCGAGCCGTCATTGAATGA
ATGGCTGAAACGCAAGGCGTTAAAAAATCAGACGCTGGGCGCTTCACGCACCTTCGTGGTGTGTGAAGCCGGTACACAGC
GTGTGGTGGGGTTCTATGCCCTCGCGTCGGGTAGCATCCAGCGTCAGGTTGCACCGGGCGCATTCCGGCGCAATATGCCT
GACCCCATTCCTGTTCTGGTACTTGGCCGATTAGCCGTTGATGAACGTTATCAACGTATGGGGATCGGTGCCGGGCTTCT
GAAAGATGCGGTACTCCGCTCCCGCAATGTAGCGCAGCAGGTAGGCAACAAAGCGTTATTGGTACATGCGTTATCTGATG
AGGCAAAAGCGTTCTACCAATACTGGGGTTTTGTCCCGTCAGAAATACAGGAACACACCTTATTATTATCGTTATGGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10384.88 Da        Isoelectric Point: 4.6702

>AT81292 WP_013316118.1 NZ_CP023467:c461362-461090 [Dickeya dadantii]
MRTEPKEMPINIRAKASQRELIDVAAKLLSKSRTEFILDAACREAEDVLLDQRLFLVNDEQYDAFIQVLESPVTDNPRVN
ALLNRKSPWE

Download         Length: 273 bp

>AT81292 NZ_CP023467:c461362-461090 [Dickeya dadantii]
ATGCGAACAGAGCCAAAAGAAATGCCGATTAATATTCGTGCTAAAGCATCACAGCGGGAGCTGATTGATGTCGCCGCTAA
ATTGCTGTCGAAATCAAGAACAGAGTTTATCCTTGATGCTGCCTGCCGTGAGGCTGAGGATGTGTTGTTGGATCAAAGGC
TGTTTCTGGTCAATGATGAACAATATGATGCTTTCATTCAGGTGTTGGAATCACCAGTCACAGATAATCCGCGTGTGAAT
GCATTACTGAACAGGAAATCTCCGTGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3N0G158

Antitoxin

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Source
ID
Structure
AlphaFold DBE0SJ01

References