Detailed information of TA system TA081271

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 2085711..2086242
• Replicon: chromosome
• Accession: NZ_CP023439
• Organism: Thauera sp. K11

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CCZ27_RS09130
• Protein ID: WP_096447507.1
• Coordinates: 2085711..2085992 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: CCZ27_RS09135
• Protein ID: WP_096447509.1
• Coordinates: 2085979..2086242 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCZ27_RS09090	2081977..2082324	+	348	WP_096447493.1	type II toxin-antitoxin system RelE/ParE family toxin	-
CCZ27_RS09095	2082321..2082653	+	333	WP_096447495.1	helix-turn-helix domain-containing protein	-
CCZ27_RS09100	2082823..2083113	-	291	WP_096447497.1	type II toxin-antitoxin system RelE/ParE family toxin	-
CCZ27_RS09105	2083110..2083400	-	291	WP_096447499.1	ribbon-helix-helix protein, CopG family	-
CCZ27_RS09110	2083487..2084221	+	735	WP_096447501.1	type I secretion C-terminal target domain-containing protein	-
CCZ27_RS09115	2084461..2084730	+	270	WP_096447503.1	type II toxin-antitoxin system ParD family antitoxin	-
CCZ27_RS23475	2084727..2084813	+	87	Protein_1815	type II toxin-antitoxin system RelE/ParE family toxin	-
CCZ27_RS09120	2084895..2085179	-	285	WP_096447505.1	type II toxin-antitoxin system RelE/ParE family toxin	-
CCZ27_RS09125	2085176..2085454	-	279	WP_096452363.1	antitoxin of toxin-antitoxin stability system	-
CCZ27_RS09130	2085711..2085992	-	282	WP_096447507.1	type II toxin-antitoxin system YafQ family toxin	Toxin
CCZ27_RS09135	2085979..2086242	-	264	WP_096447509.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CCZ27_RS09145	2086610..2086804	+	195	WP_096447511.1	type II toxin-antitoxin system VapB family antitoxin	-
CCZ27_RS09150	2086801..2087214	+	414	WP_096447513.1	PIN domain nuclease	-
CCZ27_RS09155	2087255..2088007	-	753	WP_096447515.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2042238..2097107	54869

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-84)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10802.34 Da
• Isoelectric Point: 9.1783

>T81271 WP_096447507.1 NZ_CP023439:c2085992-2085711 [Thauera sp. K11]
MRKIELTGQFKRDYKREAKGQHRVTLDSDLKPVLQALACDQPLEPRHHDHAMTGDWKDHRDCHVRPDLVLRYRKPDAGTL
QLVRLGSHSELGL

Nucleotide

• Length: 282 bp

>T81271 NZ_CP023439:c2085992-2085711 [Thauera sp. K11]
ATGCGAAAGATTGAACTGACCGGCCAATTCAAACGCGACTACAAACGTGAAGCCAAGGGGCAACATCGCGTGACGCTTGA
TAGCGACCTGAAGCCAGTCTTGCAGGCACTGGCATGCGATCAGCCACTGGAGCCCCGCCACCACGACCATGCCATGACCG
GCGACTGGAAGGATCACCGGGATTGCCACGTCAGGCCCGACCTGGTGCTGCGCTACCGGAAGCCAGACGCCGGGACATTG
CAACTCGTTCGGCTTGGCTCGCATAGCGAGCTTGGCTTGTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9509.11 Da
• Isoelectric Point: 7.0157

>AT81271 WP_096447509.1 NZ_CP023439:c2086242-2085979 [Thauera sp. K11]
MAANAVVRARIDERIKEEASVVLAAMGLTVSDAFRIMLTRIAREKALPFEPLVPNETTIAAMREARAGGLKRFDSVEALM
ADLHAKD

Nucleotide

• Length: 264 bp

>AT81271 NZ_CP023439:c2086242-2085979 [Thauera sp. K11]
ATGGCTGCAAACGCTGTTGTCCGCGCCCGCATCGACGAGCGCATCAAGGAAGAGGCGTCGGTTGTGCTGGCGGCGATGGG
GCTCACCGTGTCCGATGCCTTCCGCATCATGCTCACGCGCATAGCGCGCGAGAAGGCTTTGCCCTTCGAGCCGCTGGTTC
CGAACGAAACCACCATCGCAGCCATGCGCGAGGCTCGCGCTGGCGGCCTGAAGCGTTTCGACAGCGTTGAAGCGCTGATG
GCCGACCTGCATGCGAAAGATTGA