Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelE-RHH |
Location | 2082823..2083400 | Replicon | chromosome |
Accession | NZ_CP023439 | ||
Organism | Thauera sp. K11 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | CCZ27_RS09100 | Protein ID | WP_096447497.1 |
Coordinates | 2082823..2083113 (-) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | - |
Locus tag | CCZ27_RS09105 | Protein ID | WP_096447499.1 |
Coordinates | 2083110..2083400 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CCZ27_RS09090 | 2081977..2082324 | + | 348 | WP_096447493.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
CCZ27_RS09095 | 2082321..2082653 | + | 333 | WP_096447495.1 | helix-turn-helix domain-containing protein | - |
CCZ27_RS09100 | 2082823..2083113 | - | 291 | WP_096447497.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CCZ27_RS09105 | 2083110..2083400 | - | 291 | WP_096447499.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
CCZ27_RS09110 | 2083487..2084221 | + | 735 | WP_096447501.1 | type I secretion C-terminal target domain-containing protein | - |
CCZ27_RS09115 | 2084461..2084730 | + | 270 | WP_096447503.1 | type II toxin-antitoxin system ParD family antitoxin | - |
CCZ27_RS23475 | 2084727..2084813 | + | 87 | Protein_1815 | type II toxin-antitoxin system RelE/ParE family toxin | - |
CCZ27_RS09120 | 2084895..2085179 | - | 285 | WP_096447505.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
CCZ27_RS09125 | 2085176..2085454 | - | 279 | WP_096452363.1 | antitoxin of toxin-antitoxin stability system | - |
CCZ27_RS09130 | 2085711..2085992 | - | 282 | WP_096447507.1 | type II toxin-antitoxin system YafQ family toxin | - |
CCZ27_RS09135 | 2085979..2086242 | - | 264 | WP_096447509.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
CCZ27_RS09145 | 2086610..2086804 | + | 195 | WP_096447511.1 | type II toxin-antitoxin system VapB family antitoxin | - |
CCZ27_RS09150 | 2086801..2087214 | + | 414 | WP_096447513.1 | PIN domain nuclease | - |
CCZ27_RS09155 | 2087255..2088007 | - | 753 | WP_096447515.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2042238..2097107 | 54869 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 10771.45 Da Isoelectric Point: 10.7271
>T81270 WP_096447497.1 NZ_CP023439:c2083113-2082823 [Thauera sp. K11]
VKLVWTRPAQEDRKAIRKYIAVDNPSAALDLDELLSASAARLIDHPGLGRPGRVQGTRELVAHRNYILIYDVSGDLVRVL
RVLHAARMWPPTRSAH
VKLVWTRPAQEDRKAIRKYIAVDNPSAALDLDELLSASAARLIDHPGLGRPGRVQGTRELVAHRNYILIYDVSGDLVRVL
RVLHAARMWPPTRSAH
Download Length: 291 bp
>T81270 NZ_CP023439:c2083113-2082823 [Thauera sp. K11]
GTGAAGCTGGTTTGGACCCGGCCGGCACAGGAAGATCGAAAGGCCATCCGCAAATACATCGCAGTTGATAATCCGAGTGC
AGCGCTCGATCTCGATGAACTCCTGTCAGCAAGCGCTGCACGCCTGATCGATCATCCTGGCCTTGGCCGGCCTGGCCGCG
TTCAAGGCACGCGCGAGCTTGTCGCGCATCGCAACTACATCCTCATTTACGATGTCAGCGGCGACTTGGTGCGCGTGCTT
CGTGTCTTGCATGCGGCCCGTATGTGGCCGCCGACCAGATCAGCGCACTGA
GTGAAGCTGGTTTGGACCCGGCCGGCACAGGAAGATCGAAAGGCCATCCGCAAATACATCGCAGTTGATAATCCGAGTGC
AGCGCTCGATCTCGATGAACTCCTGTCAGCAAGCGCTGCACGCCTGATCGATCATCCTGGCCTTGGCCGGCCTGGCCGCG
TTCAAGGCACGCGCGAGCTTGTCGCGCATCGCAACTACATCCTCATTTACGATGTCAGCGGCGACTTGGTGCGCGTGCTT
CGTGTCTTGCATGCGGCCCGTATGTGGCCGCCGACCAGATCAGCGCACTGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10823.88 Da Isoelectric Point: 4.5967
>AT81270 WP_096447499.1 NZ_CP023439:c2083400-2083110 [Thauera sp. K11]
MSETTFTFRVDDDLKEQFTAAAKGRDRSGAQLLRDFMREFVKQQQEADAHDPWFRREVQIGIDAANAGDVVSAEEVEAEA
AAWRSETRRKMAGANS
MSETTFTFRVDDDLKEQFTAAAKGRDRSGAQLLRDFMREFVKQQQEADAHDPWFRREVQIGIDAANAGDVVSAEEVEAEA
AAWRSETRRKMAGANS
Download Length: 291 bp
>AT81270 NZ_CP023439:c2083400-2083110 [Thauera sp. K11]
ATGAGCGAAACAACGTTCACCTTCCGGGTCGATGACGACCTGAAAGAGCAATTCACAGCGGCAGCAAAGGGGCGCGATCG
CAGCGGTGCGCAACTCCTGCGCGATTTCATGCGCGAGTTCGTGAAGCAGCAACAAGAGGCCGACGCTCACGATCCCTGGT
TTCGCCGTGAGGTACAAATCGGCATTGACGCAGCCAATGCCGGAGATGTGGTCTCGGCCGAAGAGGTAGAAGCCGAAGCG
GCGGCCTGGCGGTCGGAGACGCGGCGAAAGATGGCCGGCGCTAATTCGTGA
ATGAGCGAAACAACGTTCACCTTCCGGGTCGATGACGACCTGAAAGAGCAATTCACAGCGGCAGCAAAGGGGCGCGATCG
CAGCGGTGCGCAACTCCTGCGCGATTTCATGCGCGAGTTCGTGAAGCAGCAACAAGAGGCCGACGCTCACGATCCCTGGT
TTCGCCGTGAGGTACAAATCGGCATTGACGCAGCCAATGCCGGAGATGTGGTCTCGGCCGAAGAGGTAGAAGCCGAAGCG
GCGGCCTGGCGGTCGGAGACGCGGCGAAAGATGGCCGGCGCTAATTCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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