Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907(toxin)
Location 2041947..2042512 Replicon chromosome
Accession NZ_CP023434
Organism Suicoccus acidiformans strain ZY16052

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CL176_RS09545 Protein ID WP_118991106.1
Coordinates 2042174..2042512 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CL176_RS09540 Protein ID WP_118991105.1
Coordinates 2041947..2042177 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CL176_RS09530 2038768..2039514 + 747 WP_118991103.1 SDR family oxidoreductase -
CL176_RS12355 2040671..2040898 + 228 WP_162890938.1 hypothetical protein -
CL176_RS09540 2041947..2042177 + 231 WP_118991105.1 AbrB family transcriptional regulator Antitoxin
CL176_RS09545 2042174..2042512 + 339 WP_118991106.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CL176_RS09550 2042747..2043457 - 711 WP_118991107.1 hypothetical protein -
CL176_RS09555 2043544..2043756 + 213 WP_162890939.1 transposase -
CL176_RS09560 2044278..2046134 + 1857 WP_118991109.1 heavy metal translocating P-type ATPase -
CL176_RS09565 2046198..2046431 + 234 WP_118991110.1 heavy-metal-associated domain-containing protein -
CL176_RS09570 2046770..2047258 + 489 Protein_1854 prolyl-tRNA synthetase associated domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12870.10 Da        Isoelectric Point: 9.4070

>T81259 WP_118991106.1 NZ_CP023434:2042174-2042512 [Suicoccus acidiformans]
MSYIPEKGDIVWLDFDPAAGKEIQKCRPALVISHIAFNRTTYFAVVCPITTTFRKFPTHVPLPKQLNTAGYVVVSQLKSI
DFKVRNIAFIEKVPTFYLKQIDQLVEYIFSKD

Download         Length: 339 bp

>T81259 NZ_CP023434:2042174-2042512 [Suicoccus acidiformans]
ATGAGTTATATTCCAGAGAAAGGTGATATCGTATGGCTTGACTTCGACCCTGCTGCGGGTAAGGAAATCCAAAAGTGTAG
ACCAGCCTTAGTAATCTCACACATTGCTTTCAATCGCACAACCTATTTCGCAGTCGTCTGTCCCATTACCACTACATTTC
GAAAGTTCCCCACACATGTCCCCCTACCGAAACAGCTGAATACGGCAGGCTATGTGGTTGTGTCCCAACTTAAGTCGATT
GATTTCAAAGTAAGAAATATCGCCTTTATCGAAAAAGTTCCAACCTTCTACTTGAAGCAAATTGACCAGTTAGTTGAATA
TATTTTTAGTAAGGATTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8750.76 Da        Isoelectric Point: 4.0742

>AT81259 WP_118991105.1 NZ_CP023434:2041947-2042177 [Suicoccus acidiformans]
MYTTRTRKQGNSIVVTLPASEEYPIASQKEYFVFYHEDGTVTLVPKIDNPFLIAEEGAYYDSEVWEDMPRAGEELL

Download         Length: 231 bp

>AT81259 NZ_CP023434:2041947-2042177 [Suicoccus acidiformans]
ATGTATACAACTAGAACACGAAAGCAAGGTAATTCAATCGTCGTGACCCTACCGGCGAGTGAGGAGTACCCTATCGCAAG
CCAGAAAGAATACTTTGTCTTCTATCATGAAGATGGAACGGTTACGCTTGTCCCTAAGATTGATAATCCTTTCTTAATTG
CTGAAGAAGGCGCATATTATGATAGTGAAGTCTGGGAGGATATGCCAAGAGCTGGGGAAGAACTACTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References